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Cell Signal Blockers

We now understand a lot more about the pathways within lymphoma cells that make them divide and keep them alive.  Often signals reaching the surface trigger a series of steps along one or more pathways for the lymphoma cell to be able to divide and survive.  Scientists have found that blocking either the signal or a key step in the pathway can make the lymphoma cells die.
A number of new medicines have been developed to target these signals and pathways.  Ibrutinib is one such new medicine that targets an important pathway in B cells and it starting to be used successfully in some B cell lymphomas and clinical trials are being utilised to work out how to best use this medicine.