Bayanin Canje-canje na Lymphoma (TL)
Canje-canjen lymphoma yana faruwa ne lokacin da lymphoma na ku ya canza, kuma ya zama lymphoma mai tsanani tare da siffofi na wani nau'i na lymphoma daban-daban. Wannan ya sha bamban da lymphoma na ku na "farkawa" ko zama mafi aiki da buƙatar magani. A wasu lokuta, kuna iya samun ƙwayoyin lymphoma marasa ƙarfi da m yayin da lymphoma ke tafiya ta hanyar canzawa.
Lymphomas marasa ƙarfi yawanci sun ƙunshi ƙananan ƙwayoyin sel masu girma a hankali. Duk da haka, idan yawancin waɗannan kwayoyin sun fara girma, kuma da sauri, lymphoma ya fara aiki kamar lymphoma mai tsanani kamar Diffus Large B-cell Lymphoma (DLBCL). Ba sabon abu ba ne lokacin da kake da ƙwayar lymphoma da ta canza, don samun ƙwayoyin lymphoma gauraye, wasu waɗanda ba su da ƙarfi wasu kuma masu tayar da hankali.
Makasudin jiyya don rashin lafiyar ku ko rikitaccen lymphoma
Yawancin lymphomas marasa ƙarfi za su bi ta matakai inda suke barci da farkawa. Duk da haka, idan lymphoma na ku ya zama mafi aiki kuma yana buƙatar magani, za ku sami jiyya da aka tsara don sarrafa lymphoma na ku.
Duk da haka, idan kuna da lymphoma mara kyau canzawa A cikin wani nau'in lymphoma mai tsanani, za ku iya samun magani da aka ba ku don warkarwa, ko sanya ƙwayar lymphoma mai tsanani zuwa gafara.
Me yasa canji ke faruwa?
Lymphoma na iya canzawa lokacin da ƙwayoyin lymphoma, ko kwayoyin halittar da ke ba da umarni ga sel ɗin ku suna haɓaka sabbin maye gurbi. Wadannan sabbin maye gurbi na iya zama sakamakon maganin cutar kansa da aka yi a baya, ko kuma na iya faruwa ba tare da sanin dalili ba. Canje-canje na kwayoyin halitta na iya canza yadda lymphoma ke tasowa da kuma halinsa, wanda zai haifar da yanayi mai tsanani.
Wanene Canjin Lymphoma ya shafa?
Duk wanda ke da ƙananan ƙwayoyin lymphoma ko ƙananan lymphoma na cikin haɗarin canji. Duk da haka yana da wuya sosai, kuma yana faruwa ne kawai a cikin mutane 1 zuwa 3 a cikin kowane 100 tare da lymphoma maras amfani kowace shekara (1-3%).
Za ku sami ɗan ƙaramin haɗari na canji idan kuna da cuta mai girma (babban ciwace ko ciwace-ciwacen daji) lokacin da aka fara gano ku tare da lymphoma maras amfani.
Mafi yawan ƙwayoyin lymphoma marasa ƙarfi waɗanda zasu iya canzawa sun haɗa da lymphoma B-cell kamar:
- Lymphoma na follicular
- Ciwon daji na Lymphocytic na yau da kullun ko ƙananan ƙwayoyin lymphoma
- Ƙwararren yanki na Lymphoma
- Nodular Lymphocyte Predominant B-cell Lymphoma (wanda ake kira Nodular Lymphocyte Predominant Hodgkin Lymphoma)
- Cutar sankarau na Mantle Cell Lymphoma
- Waldenstrom's Macroglobulinemia
Yana da mahimmanci a fahimci cewa yawancin mutanen da ke da waɗannan lymphomas ba sa canzawa.
Wasu mutanen da ke da ƙwayar lymphoma na T-cell na iya samun canji, amma waɗannan sun fi wuya.
Yaushe canji ya fi faruwa?
Canje-canje na lymphoma na iya faruwa a kowane lokaci, amma za ku iya samun canji game da shekaru 3-6 bayan an gano ku tare da lymphoma na ku.
Haɗarin canji yana raguwa sosai bayan rayuwa tare da lymphoma na ku na tsawon shekaru 15, tare da sauye-sauye bayan wannan lokacin yana da wuya sosai.
Alamun wanda zai iya nuna cewa lymphoma ya canza
Hakanan kuna iya samun alamun B yayin da lymphoma ɗinku ya ƙara aiki ko ya fara canzawa
Wadanne canje-canje ne suka fi yawa?
Wasu canje-canje sun fi kowa fiye da wasu. A ƙasa muna lissafin sauye-sauye na gama gari (ko da yake har yanzu ba kasafai ba) waɗanda ke iya faruwa.
Lymphoma mai rauni |
Zai iya canzawa zuwa lymphoma mai zuwa |
| Ciwon daji na Lymphocytic na yau da kullun/Ƙananan Lymphocytic Lymphoma (CLL/SLL) |
Canje-canje zuwa Babban B-cell Lymphoma (DLBCL) - wannan canjin ana kiransa ciwo na Richter. Fiye da wuya, CLL/SLL na iya canzawa zuwa wani nau'in nau'in ƙwayar cuta na Hodgkin na zamani. |
| Lymphoma na follicular |
Mafi yawan canji na yau da kullun shine zuwa Yada Manyan B-cell Lymphoma (DLBCL). Da wuya, zai iya canzawa zuwa lymphoma B-cell mai tsanani, tare da siffofi na DLBCL da Burkitt Lymphoma. |
| Lymphoplasmacytic Lymphoma (wanda ake kira Waldenstrom's macroglobulinemia) | Yada Babban B-cell Lymphoma (DLBCL). |
| Mantle Cell Lymphoma (MCL) | Blastic (ko blastoid) MCL. |
| Ƙwararren yanki na Lymphomas (MZL) | Yada Babban B-cell Lymphoma (DLBCL). |
| Mucosa-Associated Lymphoid Tissue Lymphoma (MALT), ƙaramin nau'in MZL | Yada Babban B-cell Lymphoma (DLBCL). |
| Nodular Lymphocyte-Mafi rinjaye B-cell Lymphoma (wanda ake kira Nodular Lymphocyte-Predominant Hodgkin lymphoma) | Yada Large B-cell Lmphoma (DLBCL). |
| Cutaneous T-cell Lymphoma (CTCL) | Large Cell Lymphoma. |
Ganewa da kuma matakan Canjawar Lymphoma
Idan likitanku ya yi zargin cewa lymphoma ɗinku ya canza za su so yin ƙarin gwaje-gwaje da dubawa. Gwaje-gwajen za su haɗa da biopsies don bincika ko ƙwayoyin lymphoma sun sami sababbin maye gurbi, kuma idan sun kasance yanzu suna yin kama da nau'in lymphoma daban-daban, kuma za a yi sikanin sikanin lymphoma.
Waɗannan gwaje-gwaje da sikanin za su yi kama da waɗanda kuka yi lokacin da aka fara gano ku da lymphoma. Bayanin daga waɗannan zai ba likitan ku bayanin da ake buƙata don ba ku mafi kyawun nau'in magani don ƙwayar lymphoma da ta canza.
Jiyya
Da zarar an kammala duk sakamakon ku daga biopsy da kuma sikanin sikanin, likitan ku zai duba su don yanke shawara mafi kyawun magani a gare ku. Hakanan likitanku na iya saduwa da ƙungiyar wasu kwararru don tattauna mafi kyawun magani kuma ana kiran wannan a Ƙungiyar da'a daban-daban (MDT) haduwa.
Likitanku zai yi la'akari da abubuwa da yawa game da lymphoma da lafiyar ku don yanke shawara idan, da kuma irin magani da ake bukata. Wasu daga cikin abubuwan da za su yi la'akari da su sun haɗa da:
- Menene canji ya faru (sabon nau'in lymphoma na ku)
- Matsayin lymphoma
- Duk wata alama da kuke samu
- Yadda lymphoma ke shafar jikin ku
- Yawan ku
- Duk wasu matsalolin likita da kuke da su ko magungunan da kuke sha
- Abubuwan da kuka zaɓa da zarar kun sami duk bayanan da kuke buƙata.
Nau'in Jiyya
Canje-canjen lymphoma yana buƙatar a bi da shi ta hanya ɗaya da ƙwayar lymphoma mai tsanani. Jiyya na iya haɗawa da:
- Haɗuwa chemotherapy
- Kwayar cutar Monoclonal
- Autologous kara cell dashi (idan lafiya ta isa)
- Radiotherapy (yawanci tare da chemotherapy)
- CAR T-cell far (Chimeric antigen receptor T-cell far - bayan 2 kafin hanyoyin kwantar da hankali)
- immunotherapy
- Magungunan da aka yi niyya
- Shiga gwaji na asibiti
Hasashen Canjin Lymphoma (TL)
Yawancin lymphomas masu tsanani za a iya warkewa, ko kuma suna da lokaci mai tsawo na gafara bayan jiyya. Don haka, akwai bege cewa lokacin da aka ba ku magani za a iya warkewa, ko kuma ku sami gafara mai ɗorewa daga mafi muni, rikiɗar lymphoma. Koyaya, har yanzu kuna buƙatar bin diddigin ku bayan jiyya don bincika alamun sake dawowa.
Lymphomas marasa ƙarfi a mafi yawan lokuta ba za a iya warkewa ba, don haka ko da bayan jiyya na lymphoma da aka canza, za ku iya samun wasu ƙwayoyin lymphoma marasa ƙarfi, kuma don haka likitanku zai so ya duba wannan ma.
Tambayi likitan ku irin damar da za ku samu na warkewa, shiga cikin gafara kuma har yanzu kuna rayuwa tare da lymphoma maras kyau bayan jiyya ga lymphoma da kuka canza.
Summary
- Lymphoma da aka canza yana da wuya sosai, tare da kusan 1-3 cikin kowane mutane 100 da ke da ƙwayar lymphoma mara kyau suna samun canji kowace shekara.
- Canji ya fi kowa a cikin mutanen da ke da lymphoma na B-cell, amma zai iya faruwa a cikin mutanen da ke da lymphoma na T-cell.
- Canji ya fi zama ruwan dare shekaru 3-6 bayan an gano ku tare da lymphoma mara kyau, kuma da wuya sosai bayan shekaru 15.
- Canza Lymphoma na iya faruwa idan kwayoyin halittarku ko ƙwayoyin lymphoma suka haɓaka sabbin maye gurbi, suna canza yadda lymphoma ke girma da kuma hali.
- Lymphoma da aka canza ya bambanta da lymphoma mara kyau "farkawa" kuma yana ƙara aiki.
- Har yanzu akwai yuwuwar warkewa daga ƙwayar lymphoma mai saurin canzawa, amma zaku iya ci gaba da rayuwa tare da lymphoma maras amfani bayan jiyya.
- Jiyya don canza lymphoma za a yi niyya don warkewa, ko sanya ƙwayar lymphoma mai tsanani cikin gafara.
- Bayar da rahoton duk sababbi da tabarbarewa bayyanar cututtuka, ciki har da B-alamomi ga likitan ku.
