Nānā nui o PCNSL
Hoʻokumu ʻia ka PCNSL i ka wā e hana ʻia ai nā lymphocytes B-cell (B-cell) i loko o ka ʻiʻo lymphoid o ka lolo a / a i ʻole ke kuamoʻo. Hiki i ka PCNSL ke hoʻomaka ma nā papa e hana i ka uhi waho o ka lolo (meninges) a i ʻole ma nā maka (ocular lymphoma).
I kekahi manawa hiki ke hoʻomaka ka lymphoma ma nā wahi ʻē aʻe o ke kino a laha i ka CNS. He ʻokoʻa kēia i ka PCNSL a ʻokoʻa ka mālama ʻia. Inā ua hoʻomaka ma waho o ka CNS a laha i ka CNS ua kapa ʻia ʻo ia ka lymphoma CNS lua.
ʻAʻole ʻike ʻia ke kumu o ka PCNSL e like me ke ʻano o nā lymphomas he nui. ʻOi aku ka hopena o ka poʻe ma waena o 50 a 60 mau makahiki, me ka awelika o ka makahiki o ka maʻi ma kahi o 60 mau makahiki, akā hiki ke loaʻa i kēlā me kēia makahiki. ʻOi aku ka maʻamau o ka PCNSL i nā poʻe i nāwaliwali ka ʻōnaehana pale, ʻo ia paha ke kumu:
- ʻO ka maʻi HIV (human immunodeficiency virus) - ʻaʻole maʻamau kēia i kēia manawa ma muli o ka loaʻa ʻana o nā lāʻau antiviral kūpono
- Nā lāʻau lapaʻau – nā mea i hoʻohana ʻia e hoʻopau i ka ʻōnaehana pale, e like me ka hoʻololi ʻana i ke kino a i ʻole nā ʻano lapaʻau immunosuppressive ʻē aʻe no nā maʻi autoimmune e like me ka rheumatoid arthritis.
Hiki ke ho'ōla 'ia ka PCNSL?
Hiki i nā lymphoma koʻikoʻi ke pane maikaʻi i nā lāʻau lapaʻau me ka chemotherapy no ka mea e hana ana ka chemotherapy ma ka pepehi ʻana i nā cell ulu wikiwiki. Nui nā kumu, e pili ana inā e ho'ōla ʻia ʻoe mai kāu lymphoma a ʻaʻole paha. Hiki ke ho'ōla 'ia ka po'e he nui, loa'a paha i kekahi po'e ke kala kala - kahi i koe 'ole o ka lymphoma i loko o kou kino, a laila hiki ke ho'i hou (ho'i mai) a pono e lapa'au hou aku.
No ka ʻike hou aku e pili ana i kou manawa e ola ai, e kamaʻilio me kāu kauka haematologist a i ʻole oncologist.
He aha ka hana a ka Central Nervous System (CNS)?
ka ʻōnaehana ʻōnaehana waena (CNS) ʻo ia ka ʻāpana o ko mākou kino e hoʻomalu i nā hana āpau o ke kino. Aia i loko o ko mākou lolo, spinal cord a me nā maka.
ʻO ka lolo
Hoʻokumu ʻia ko mākou lolo i:
- Cerebrum - ke hoʻomalu nei kēia i kā mākou kamaʻilio a me ka ʻike, ko mākou mau manaʻo a me ka neʻe manawaleʻa (nā neʻe a mākou e hoʻoholo ai e hana)
- Cerebellum - kōkua me ka neʻe ʻana a mālama i kā mākou kaulike
- ʻŌnaehana lolo - hoʻomalu i nā hana koʻikoʻi o ke kino, e like me ko mākou hanu, ka puʻuwai a me ke koko
ʻO ka iwi kuamoʻo
Holo ko mākou kuamoʻo mai ko mākou lolo a iho i ko mākou kua i loko o nā iwi o ka iwi kuamoʻo. Hoʻopili pololei ke ʻano o nā aʻalolo i ke kuamoʻo. Lawe nā aʻalolo i ka ʻike e pili ana i ke ʻano o ke kino a lawe i nā memo i ko mākou lolo a i ke koena o ko mākou kino, e hoʻomalu i ko mākou mau ʻiʻo, a me nā hana a pau o ko mākou kino.
Pehea e pale ʻia ai ko mākou CNS?
Hoʻokaʻawale ʻia ko mākou CNS mai ke koena o ko mākou kino a pale ʻia mai ka ʻeha, ka maʻi a me ka maʻi ma nā ʻano he nui.
- ka nā meninges he mau papa pale o ka ʻiʻo e uhi ana i ka lolo a me ke kuamoʻo – ʻo ia ka mea e ʻā ai i ka 'meningitis'
- He wai kūikawā i kapa ʻia 'wai cerebrospinal'(CSF) hoʻopuni i ka lolo a me ke kuamoʻo e hoʻopaʻa iā lākou - loaʻa ia ma ka hakahaka ma waena o nā meninges a me ka lolo a me ke kuamoʻo.
- ka ka pale i ke koko hoʻopuni i ko mākou lolo - he mea pale ia o nā pūnaewele a me nā kīʻaha koko e ʻae wale i kekahi mau mea i ka lolo. Mālama kēia iā ia mai nā kemika ʻino a me nā maʻi maʻi, a ke pale a hoʻopilikia paha i nā lāʻau lapaʻau chemotherapy e hele ana mai ke koko i ka lolo.
No ka hoʻomaopopo ʻana i ka PCNSL pono ʻoe e ʻike iki e pili ana i kāu lymphocytes B-Cell.
ʻO nā lymphocytes pūnaewele B:
- He ʻano o ke koko keʻokeʻo
- E hakakā i ka maʻi a me nā maʻi e mālama pono iā ʻoe.
- E hoʻomanaʻo i nā maʻi i loaʻa iā ʻoe i ka wā ma mua, no laila inā loaʻa hou iā ʻoe ka maʻi like, hiki i ka ʻōnaehana pale o kou kino ke hakakā me ka ʻoi aku ka maikaʻi a me ka wikiwiki.
- Hana ʻia i loko o kou iwi iwi (ʻo ka ʻāpana spongy i waenakonu o kou mau iwi), akā maʻamau e noho i kāu ʻōnaehana lymphatic e komo pū ana me:
- lymph aka wahi
- nā moku lymphatic a me ka wai lymph
- nā kino - spleen, thymus, tonsils, appendix
- ʻiʻo lymphoid
- Hiki ke hele ma kāu ʻōnaehana lymphatic, i kekahi ʻāpana o kou kino e hakakā ai i ka maʻi a i ʻole ka maʻi.
He aha ka hana i ka wā e ulu ai ʻo PCNSL?
Hoʻokumu ʻo PCNSL i ka wā e loaʻa ai nā lymphocytes maʻi maʻi i loko o kāu ʻōnaehana nūnū waena (CNS), ʻo ia hoʻi kou lolo, spinal cord, maka, cranial nerves a me ka papa pale o ka ʻiʻo e uhi ana i kou lolo a me ke kuamoʻo i kapa ʻia nā meninges.
Ke loaʻa iā ʻoe ka PCNSL, kāu lymphocytes maʻi maʻi:
- E ulu me ke kaohi ole
- ʻAʻole e hana maikaʻi e hakakā i nā maʻi a me nā maʻi
- Hiki ke lilo i ʻoi aku ka nui ma mua o ka pono a hiki ke nānā ʻokoʻa i kāu mau pūnaewele B olakino
- Hiki ke hoʻoulu i ka lymphoma i loko o kou lolo, spinal cord a me nā maka.
- Ma muli o nā pale pale a puni ko mākou CNS, ʻaʻole laha pinepine ʻo PCNSL i nā ʻāpana ʻē aʻe o kou kino e like me nā ʻano lymphoma ʻē aʻe e hiki ai, akā naʻe, hiki iā lākou ke hoʻolaha i nā hōʻike i nā kāne.
Nā hōʻailona ke loaʻa ka lymphoma i kāu Pūnaehana Nervous Central (CNS)
ʻO nā hōʻailona o ka lymphoma i kāu CNS pili i nā hana o kou lolo, nā maka a me ke kuamoʻo. E hilinaʻi lākou i ka ʻāpana o kāu CNS i hoʻopili ʻia a hiki ke komo i kēia mau mea:
- headaches
- nā hoʻololi i kāu ʻike
- huikau a hoʻololi hoʻomanaʻo
- he hoʻololi i ka ʻike (e lilo i ka hiamoe a me ka pane ʻole)
- paʻakikī i ka ʻōlelo a i ʻole ke ale ʻana
- hoʻololi i kou ʻano a i ʻole kou ʻano
- hoʻopaʻa ʻia (kūpono)
- nausea a me ka luaʻi
- pau ka ʻai (ʻaʻole makemake e ʻai) a me ke kaumaha
- pilikia ka hele ʻana i ka lua
- pilikia i ka hele ʻana, unsteadiness a hāʻule paha
- nawaliwali, numbness a i ʻole nā manaʻo tingling.
ʻO ka ʻike, ka hoʻonohonoho ʻana a me ka helu ʻana o PCNSL
Inā kānalua kāu kauka he lymphoma paha ʻoe, pono ʻoe e hana i kekahi mau hoʻokolohua. ʻAʻole like me nā ʻano subtypes ʻē aʻe o lymphoma, ʻaʻole i hana ʻia ka hoʻonohonoho ʻana inā loaʻa iā ʻoe ka PCNSL no ka mea ua paʻa ka lymphoma i kāu ʻōnaehana nerve waena (CNS). ʻO ka hoʻolaha ʻana ma waho o ka CNS maʻamau i nā kāne wale nō a i nā testes wale nō.
Manaʻo mau ʻia ʻo PCNSL he lymphoma kiʻekiʻe, ʻo ia hoʻi, he mea ʻino. E ulu wikiwiki a hiki ke neʻe koke i kāu CNS. ʻOkoʻa loa ke ʻano o nā pūnaewele B maʻi ʻaʻai (lymphoma cell) mai kāu mau pūnaʻi B olakino no ka mea e ulu wikiwiki ana lākou a ʻaʻohe manawa e hana pono ai.
Kaomi ma ke poʻomanaʻo ma lalo nei e aʻo hou e pili ana i ke ʻano o nā hoʻokolohua āu e ʻike ai, a e aʻo hou e pili ana i kāu PCNSL.
ʻO Biopsy
No ka ʻike ʻana i ka PCNSL pono ʻoe i kahi biopsy. ʻO ka biopsy kahi kaʻina hana e wehe ai i kahi ʻāpana, a i ʻole nā poʻo lymph i hoʻopilikia ʻia. I ka wā o ke kaʻina hana, loaʻa paha iā ʻoe ka lāʻau anesthetic maʻamau a kūloko paha i mea e hōʻoluʻolu ai ʻoe, a i ʻole ʻoe e ala ʻole i ka wā e hana ʻia ai.
ʻO ke ʻano o ka biopsy e hana ʻia e pili ana i kahi e loaʻa ai ka lymphoma.
Inā manaʻo ʻia ka lymphoma i loko o kāu:
- ʻO ka lolo - he neurosurgeon (he loea i ka ʻike a me ka mālama ʻana i nā pilikia me ka CNS) lawe i kahi biopsy lolo. E hoʻoneʻe ʻia nā puʻupuʻu (a i ʻole nā laʻana o nā puʻupuʻu) i loko o kou lolo me ka hoʻohana ʻana i ka CT scan e kōkua i ke alakaʻi ʻana i ka nila biopsy i kahi kūpono. Kapa ʻia kēia a 'stereotactic biopsy'. E loaʻa iā ʻoe kahi anesthetic maʻamau no kēia kaʻina hana no ka mea he mea nui ʻaʻole e neʻe.
- Maka - hiki i ke kauka ophthalmologist (ka loea i nā maʻi a me nā ʻeha o ka maka) ke lawe i kahi liʻiliʻi o ka vitreous (mea like me ka gel i loko o kou maka) e nānā i nā sela lymphoma.
- Ka iwi kuamoʻo - hiki i ke kauka lapaʻau kūikawā ke lawe i kahi biopsy mai kou iwi kuamoʻo.
Nā ho'āʻo koko
Lawe pū ʻia nā hoʻāʻo koko i ka wā e hoʻāʻo ai e hoʻopaʻa i kou lymphoma, akā ma ka mālama ʻana i hiki i ke kauka ke hoʻomaopopo maikaʻi i kou olakino holoʻokoʻa, a e hōʻoia i ka hana pono o kāu mau kino e hoʻokō ai i ka mālama ʻana.
Hāʻawi pinepine kēia scan i nā kiʻi maikaʻi loa o kou lolo a me nā ʻāpana ʻē aʻe o ka CNS a hiki ke ʻike pū i ka hoʻopaʻa ʻana i ka spinal cord.
Hana ʻia kēia mau scans e ʻike i ka lymphoma ma nā wahi ʻē aʻe o ke kino. Hāʻawi lākou i nā kiʻi kikoʻī e hāʻawi i ka ʻike hou aku ma mua o kahi X-ray maʻamau. Hiki ke hana ʻia e nānā i nā iwi ma kou iwi kuamoʻo.
Hoʻohana pinepine ʻia kēia ʻano scan me ka CT scan e ʻike i ka lymphoma ikaika ma nā wahi ʻē aʻe o kou kino. Lawe ia i ke kiʻi o loko o kou kino holoʻokoʻa. E hāʻawi ʻia ʻoe i kahi nila me kekahi lāʻau lapaʻau e hoʻomoʻa ai nā cell cancerous e like me nā cell lymphoma. Kōkua ka lāʻau lapaʻau i ka PET scan e ʻike i kahi o ka lymphoma a me ka nui a me ke ʻano ma ke kuhikuhi ʻana i nā wahi me nā cell lymphoma. Kapa ʻia kēia mau mea i kekahi manawa he "wela".
Ma muli o ka pili ʻana o PCNSL i nā maka, pono paha ʻoe i nā hoʻokolohua ophthalmic like ʻole. E hoʻohana ke kauka ophthalmologist (ka loea maka) i ka ophthalmoscope - he mea hana me ka māmā a me ka lens hoʻonui liʻiliʻi - e nānā maikaʻi i loko o kou maka. Hiki ke hana ʻia kekahi mau hoʻāʻo kiʻi a kōkua kēia i ka ophthalmologist e nānā i ka ʻōpū a me ka ʻike inā ua laha ke kanesa.
Pono paha kahi biopsy o ka maka. Kapa ʻia kēia he vitrectomy. Hoʻokomo ʻia kahi mea kani liʻiliʻi i loko o ka maka a lawe ia i nā laʻana o ka vitreous like me ka jelly, ʻo ia ka mea e hoʻopiha ai i ka waena o ka maka.
ʻO ka ultrasound testicular no nā kāne he hōʻike e loaʻa ai nā kiʻi o nā testicles a me nā ʻiʻo a puni i ka scrotum. Hiki ke mālama ʻia kēia ultrasound e like me ka laha ʻana o kekahi PCNSL i nā hōʻike.
Results
ʻO ke kali ʻana i kāu mau hopena a pau e hiki ke lilo i manawa kaumaha loa iā ʻoe a me kāu poʻe aloha. He mea nui e kamaʻilio e pili ana i kou manaʻo a e wehe pū me ka poʻe a puni ʻoe i kāu mea e pono ai. Nui ka poʻe e makemake e kōkua, akā ʻaʻole maopopo iā lākou pehea ma ka hōʻike ʻana iā lākou i kāu mea e pono ai, hiki iā ʻoe ke kōkua iā lākou e hāʻawi i ke kākoʻo āu e pono ai.
Hiki paha ke kōkua i ka hoʻomaka ʻana e hoʻolālā i kāu mea e pono ai i nā mahina e hiki mai ana inā pono ʻoe e mālama. Ua hoʻokomo mākou i kekahi mau ʻōlelo aʻoaʻo ma kā mākou ʻO ke ola me Lymphoma - The Practical Stuff webpage. Kaomi ma ka loulou ma lalo nei e kuhikuhi ʻia i kēlā ʻaoʻao.
Hiki iā ʻoe ke kelepona i kā mākou Nurse Hotline e kamaʻilio me kekahi o kā mākou Lymphoma Care Nurses. E kaomi wale i ke pihi Hoʻokaʻaʻike iā mākou ma lalo o kēia ʻaoʻao.
Makemake paha ʻoe e hui pū me kekahi o kā mākou ʻaoʻao pāpaho pūnaewele e kamaʻilio me nā poʻe ʻē aʻe e noho pū ana. E hoʻohui me kā mākou mau ʻaoʻao kaiapili ma ke kaomi ʻana i nā loulou ma luna o ka ʻaoʻao.
Lapaʻau no PCNSL
ʻO ka loaʻa ʻana o ka ʻike kūpono hiki ke kōkua iā ʻoe e hōʻoluʻolu a ʻike i ka mea e manaʻo ai, a hiki ke kōkua iā ʻoe e hoʻolālā i mua no kāu mea e pono ai. Akā hiki ke paʻakikī ke ʻike i nā nīnau e nīnau ai ke hoʻomaka ʻoe i ka mālama ʻana. Inā ʻaʻole ʻoe ʻike, ʻaʻole ʻoe, pehea ʻoe e ʻike ai i ka mea e nīnau ai?
Ua hōʻuluʻulu mākou i kahi papa inoa o nā nīnau āu e ʻike ai he kōkua. ʻOiaʻiʻo, kū hoʻokahi ke kūlana o kēlā me kēia kanaka, no laila ʻaʻole i uhi kēia mau nīnau i nā mea āpau, akā hāʻawi lākou i kahi hoʻomaka maikaʻi. Kaomi ma ka loulou ma lalo nei e ʻimi i kahi kope PDF hiki iā ʻoe ke hoʻoiho a paʻi inā makemake ʻoe.
Mālama i ka momona
He kāne a he wahine paha ʻoe, hiki i nā lāʻau lapaʻau anti-cancer ke hoʻopilikia i kou momona - kou hiki ke hana i nā pēpē. Inā makemake ʻoe e loaʻa nā pēpē ma hope o ka mālama ʻana, a ʻaʻole maopopo inā makemake ʻoe, e kamaʻilio me kāu kauka e pili ana i nā koho i loaʻa e kōkua i ka pale ʻana i kou momona i ka wā mālama.
Nānā o nā ʻano lapaʻau
Kaomi ma nā paheʻe ma lalo no ka ʻike ʻana i nā ʻano lapaʻau like ʻole e hāʻawi ʻia iā ʻoe e mālama i kāu PCNSL.
ʻO ka lāʻau lapaʻau mua
Pono ʻoe e hoʻomaka i ka lāʻau lapaʻau ma hope koke o ka hoʻi ʻana mai o kāu mau hopena hōʻike. I kekahi mau hihia, hiki iā ʻoe ke hoʻomaka ma mua o ka loaʻa ʻana o nā hopena hōʻike. Nui paha kou mau manaʻo e pili ana i kāu e hoʻokō ai, pehea e mālama ai ma ka home, a i ʻole e loaʻa paha ʻoe i ka maʻi.
E hōʻike i kāu hui lapaʻau inā manaʻo ʻoe makemake ʻoe i ke kākoʻo hou aku. Hiki paha iā lākou ke kōkua ma ke kuhikuhi ʻana iā ʻoe e ʻike i kahi limahana a i ʻole kekahi ʻoihana mālama ola kino e kōkua iā ʻoe e hoʻoponopono i kekahi mau pilikia o ka nohona o kēlā me kēia lā āu e alo ai. Hiki iā ʻoe ke hele aku i ka Lymphoma Care Nurses ma ke kaomi ʻana i ka pihi "Contact us" ma lalo o kēia ʻaoʻao.
Ke hoʻomaka ʻoe i ka lapaʻau no ka manawa mua, ua kapa ʻia ʻo ia 'first-line treatment'. Loaʻa paha iā ʻoe ma mua o hoʻokahi lāʻau lapaʻau, a hiki i kēia mau mea ke komo i ka radiotherapy, chemotherapy a i ʻole kahi antibody monoclonal.
Hiki ke komo i ka lāʻau lapaʻau mua maʻamau:
Methotrexate kiʻekiʻe
Hiki ke hui pū ʻia me ka ʻole o ka antibody monoclonal, rituximab.
MATRIx
He hui kēia o nā lāʻau lapaʻau like ʻole a me kahi antibody monoclonal - methotrexate, cytarabine, thiotepa a me rituximab - no ka PCNSL hou i ʻike ʻia.
R-MPV (Mahele mua a me ʻelua)
Mahele hoʻokahi - Monoclonal antibody (rituximab) a me ka hui pū ʻana o ka chemotherapy me ka methotrexate, procarbazine a me vincristine.
Mahele ʻelua - ʻO ka chemotherapy kiʻekiʻe - cytarabine
Methotrexate a me ka cytarabine
He hui pū ʻana o ʻelua chemotherapies no ka PCNSL i ʻike hou ʻia.
ʻO ka chemotherapy Intrathecal
ʻO kēia ka chemotherapy i hāʻawi ʻia i loko o ka wai o ke kuamoʻo ma ke ʻano o ka lumbar puncture. Hana ʻia kēia inā loaʻa ka lymphoma i loko o kou wai kuamoʻo.
Ke komo ʻana i ka hoʻokolohua lapaʻau
Hiki i kēia mau mea ke komo i nā hoʻokolohua lapaʻau no nā lāʻau lapaʻau i kuhikuhi ʻia a me nā lāʻau lapaʻau ʻē aʻe. E nīnau i kāu kauka inā kūpono ʻoe i nā hoʻokolohua lapaʻau lapaʻau mua.
ʻO ka Radiotherapy a i ʻole ka hoʻololi ʻana i ke ʻano o ke kino
Inā pane ka lymphoma i ka chemotherapy, hiki i kāu hui lapaʻau ke hōʻike i ka radiotherapy holoʻokoʻa-lolo a i ʻole ka hoʻololi ʻana i ke ʻano o ke kino (e nana maluna). ʻO kēia nā lāʻau lapaʻau consolidation, ʻo ia hoʻi, hoʻohana ʻia lākou e hōʻemi i ka hopena o ka hoʻi hou ʻana ma hope o ka mālama maikaʻi ʻana.
Laina lua a me ka hoomau ana
Inā hoʻi hou kāu lymphoma CNS (hoʻi mai) a ʻaʻole ʻae ʻia (ʻaʻole pane) i ka lāʻau lapaʻau, aia paha nā lāʻau lapaʻau ʻē aʻe.
ʻO ka lāʻau lapaʻau i loaʻa iā ʻoe inā hoʻi hou ʻoe a loaʻa paha ka PCNSL refractory i kapa ʻia ka lāʻau lapaʻau lua. ʻO ka mālama ʻana e pili ana i kou kūpono i kēlā manawa, he aha kāu lapaʻau i loaʻa ai a pehea ka hopena o ka lymphoma iā ʻoe. Hiki i kāu kauka ke kamaʻilio iā ʻoe ma o kāu mau koho, ʻo ia paha:
- ʻO ka chemotherapy ʻoi aku ka ikaika (ʻoi aku ka ikaika), ma muli paha o ka hoʻololi ʻana i nā pūnaewele autologous (ʻaʻole kūpono i kekahi poʻe).
- Radiotherapy – inā ʻaʻole i hāʻawi ʻia.
- Hāʻawi ʻia nā lāʻau palliative me ka manaʻo e hoʻopau i nā hōʻailona.
- Ke komo ʻana i ka hoʻokolohua lapaʻau.
Nā ho'āʻo hoʻokolohua
Manaʻo ʻia ʻo kēlā me kēia manawa e pono ai ʻoe e hoʻomaka i nā lāʻau lapaʻau hou āu e nīnau ai i kāu kauka e pili ana i nā hoʻokolohua lapaʻau hiki iā ʻoe ke kūpono.
He ala koʻikoʻi nā hoʻokolohua lapaʻau e ʻimi ai i nā lāʻau hou, a i ʻole nā hui pū ʻana o nā lāʻau e hoʻomaikaʻi ai i ka mālama ʻana i ka PCNSL i ka wā e hiki mai ana. Hiki iā lākou ke hāʻawi iā ʻoe i kahi manawa e hoʻāʻo ai i kahi lāʻau hou, hui pū ʻana o nā lāʻau lapaʻau a i ʻole nā lāʻau lapaʻau ʻē aʻe āu e hiki ʻole ai ke loaʻa ma waho o ka hoʻokolokolo. Inā makemake ʻoe e komo i kahi hoʻokolohua lapaʻau, e nīnau i kāu kauka i nā hoʻokolohua lapaʻau āu e kūpono ai.
Nui nā lāʻau lapaʻau a me nā hui lāʻau hou e hoʻāʻo ʻia nei i nā hoʻokolohua lapaʻau a puni ka honua no nā poʻe me ka PCNSL hou a hoʻi hou. ʻO kekahi mau lāʻau lapaʻau e nānā ʻia nei:
- Ibrutinib (Imbruvica®)
- ʻO Zanubrutinib (Brukinsa®) a me Tiselizumab
- Pembrolizumab (Keytruda®)
- GB5121 - he mea hoʻopaneʻe BTK hiki ke lolo
Ka wānana no PCNSL
ʻO Prognosis ka huaʻōlelo i hoʻohana ʻia e wehewehe i ke ala o kou maʻi, pehea e pane ai i ka mālama ʻana a pehea ʻoe e hana ai i ka wā a ma hope o ka mālama ʻana.
Nui nā kumu e kōkua ai i kāu wānana a ʻaʻole hiki ke hāʻawi i kahi ʻōlelo holoʻokoʻa e pili ana i ka wānana.
Nā mea hiki ke hoʻopili i ka wānana
ʻO kekahi mau mea e pili ana i kāu prognosis penei:
- ʻO kou makahiki a me kou olakino holoʻokoʻa i ka manawa o ka maʻi maʻi
- Pehea ʻoe e pane ai i ka lāʻau lapaʻau
I kekahi manawa, hoʻopau koke nā hōʻailona o ka lymphoma CNS me ka mālama ʻana. ʻO ka hoʻomaʻamaʻa mua ʻana me nā steroid hiki ke hana maikaʻi loa i ka hoʻomaha ʻana i nā hōʻailona. Akā naʻe, ulu mālie nā ʻiʻo aʻalolo, a hiki ke lōʻihi i kekahi manawa no ka hoʻomaikaʻi ʻana o nā hōʻailona. ʻIke paha kekahi o ʻoukou i ka hoʻomaikaʻi mālie ʻana i nā hōʻailona, akā naʻe, ʻike paha nā hōʻailona ʻaʻole hiki ke hoʻoholo piha, ʻoiai inā aia lākou ma mua o ka mālama ʻana.
Ke kiʻi nei i ke kākoʻo
Hiki i kāu hui lapaʻau ke kākoʻo i kou ola hou ʻana ma ke kuhikuhi ʻana iā ʻoe i nā loea kūpono. Inā ʻike ʻoe i ka nāwaliwali o ka ʻiʻo a me ka nalo ʻana o ka ikaika a ʻaʻole hoʻi e hoʻōla koke, pono ʻoe e noʻonoʻo e ʻike i kahi physiotherapist a / a i ʻole ka mea lapaʻau hana no ka mea hiki iā lākou ke hāʻawi i ke kōkua a me ka ʻōlelo aʻo e hoʻomaikaʻi i ka maikaʻi o ke ola. Hiki i kā lākou kōkua ke ho'ōki i nā hōʻailona mai ka ulu ʻana a i ʻole nā pilikia ʻē aʻe e ulu ana i ka wā lōʻihi.
Hiki i nā psychologists ke hāʻawi i ke kākoʻo inā loaʻa nā pilikia noʻonoʻo (noʻonoʻo), e like me ka hoʻomanaʻo a i ʻole nā pilikia nānā. Hiki i nā kānaka kālaiʻike a me nā kākā'ōlelo ke kākoʻo i ka hopena o kou lymphoma.
He mea nui e hoʻomaopopo ua hoʻomaikaʻi nui ʻia nā hoʻolālā lapaʻau no PCNSL i nā makahiki i hala iho nei. Eia naʻe, hiki i ka PCNSL ke paʻakikī i ka mālama ʻana, a ʻo kekahi mau lāʻau lapaʻau hiki ke hoʻoulu i nā pilikia neurological lōʻihi (pilikia me ka lolo a me nā maka). E ulu aʻe kēia mau pilikia inā loaʻa ʻoe i ka lymphoma CNS i kou wā ʻelemakule.
Ola - Noho pū me, a ma hope o ke kanesa
ʻO ke ola olakino, a i ʻole kekahi mau loli ola maikaʻi ma hope o ka mālama ʻana he mea kōkua nui ia i kou ola hou ʻana. Nui nā mea hiki iā ʻoe ke hana e kōkua iā ʻoe e ola maikaʻi ma hope o Burkitt's.
He nui ka poʻe i ʻike ma hope o ka hōʻoia ʻana i ka maʻi kanesa, a i ʻole ka mālama ʻana, e loli ana kā lākou mau pahuhopu a me nā mea nui i ke ola. ʻO ka ʻike ʻana i ke ʻano o kāu 'maʻamau hou' hiki ke hoʻolōʻihi i ka manawa a hoʻonāukiuki. He ʻokoʻa paha nā manaʻolana o kou ʻohana a me kou mau hoaaloha. Hiki paha iā ʻoe ke kaʻawale, luhi a i ʻole kekahi mau manaʻo like ʻole e loli i kēlā me kēia lā.
ʻO nā pahuhopu nui ma hope o ka mālama ʻana i kāu lymphoma ʻo ka hoʻi ʻana i ke ola a:
- e ʻeleu i kāu hana, ʻohana, a me nā kuleana ola ʻē aʻe
- e hoʻemi i nā hopena ʻaoʻao a me nā hōʻailona o ka maʻi kanesa a me ka mālama ʻana
- ʻike a mālama i nā hopena hope loa
- kōkua iā ʻoe e kūʻokoʻa e like me ka hiki
- hoʻomaikaʻi i kou maikaʻi o ke ola a mālama i ke olakino noʻonoʻo maikaʻi
Hiki ke hāʻawi ʻia iā ʻoe nā ʻano hoʻolaʻa maʻi kanesa. Hiki i kēia ke manaʻo i kekahi o ka laulā ākea o na lawelawe e like me:
- kino kino, hooponopono eha
- hoʻolālā meaʻai a me ka hoʻoikaika kino
- ka manaʻo, ka ʻoihana a me ke aʻo kālā.
hōʻuluʻulu manaʻo
- ʻO ka Lymphoma Pūnaehana Nūnū Kūwaena (PCNSL) kahi subtype koʻikoʻi kiʻekiʻe o Non-Hodgkin Lymphoma i ulu ʻia i loko o kāu ʻōnaehana nerve waena (CNS).
- ʻAʻole laha maʻamau ka PCNSL ma waho o ka CNS akā hiki ke laha i nā hōʻike i nā kāne.
- He ʻokoʻa ka PCNSL mai nā lymphomas e hoʻomaka ana ma nā wahi ʻē aʻe o ke kino a hoʻolaha i ka CNS (secondary CNS lymphoma) a pono e mālama ʻia i kahi ʻokoʻa.
- ʻO nā hōʻailona o PCNSL e pili ana i kahi o ka lymphoma, me nā hōʻailona e pili ana i nā hana o kou lolo, spinal cord a me nā maka.
- Nui nā ʻano hoʻāʻo ʻokoʻa e pono ai ʻoe e hōʻoia i ka PCNSL, a hiki i kēia mau mea ke komo i nā kaʻina hana kahi i hāʻawi ʻia ai ʻoe i kahi anesthesia āpau a kūloko paha.
- He ʻokoʻa ka lāʻau lapaʻau no ka PCNSL mai nā ʻano subtypes ʻē aʻe o ka lymphoma no ka mea pono nā lāʻau lapaʻau e hele i loko o kou pale koko-lolo e hiki ai i ka lymphoma.
- Hiki i nā hōʻailona ke hoʻomaikaʻi i kekahi manawa ma hope o ka mālama ʻana ma muli o ka ulu lohi o nā pūnaʻi nerve, akā hiki ke hoʻomaikaʻi koke nā hōʻailona ʻē aʻe.
- E kamaʻilio me kāu kauka e pili ana i kou manawa e ola ai a me nā mea e manaʻo ʻia mai kāu mālama ʻana.
- ʻAʻole ʻoe hoʻokahi. Inā makemake ʻoe e kamaʻilio me kekahi o kā mākou Lymphoma Care Nurses e pili ana i kāu lymphoma, nā lapaʻau a me nā koho e kaomi i ke pihi Hoʻokaʻaʻike iā mākou ma lalo o ka pale.
