PBAC ndi bungwe lodziyimira pawokha la akatswiri losankhidwa ndi Boma la Australia. Mamembala akuphatikizapo madokotala, akatswiri azaumoyo, azachuma azaumoyo ndi oyimira ogula.
Udindo wawo ndikupangira mankhwala atsopano oti alembedwe pa pharmaceutical benefits scheme (PBS). Palibe mankhwala atsopano omwe angatchulidwe pokhapokha ngati komiti ipereka malingaliro abwino. PBAC imakumana katatu pachaka, nthawi zambiri Marichi, Julayi ndi Novembala.
Patsambali:
Zokambirana zomwe zikubwera za PBAC:
November 2020
Kupereka kwa Lymphoma ndi CLL muzotsatira zomwe zikubwera
November 2020 lymphoma/CLL zoperekedwa pa ajenda
| Mtundu wogonjera | Dzina la mankhwala ndi wothandizira | Mtundu wa mankhwala ndi ntchito | Mndandanda womwe wafunsidwa ndi wothandizira & cholinga |
| Mndandanda watsopano (kutumiza kochepa) | Anayankha | Chronic lymphocytic leukemia (CLL); Small lymphocytic lymphoma (SLL); Malaya cell lymphoma | Kufunsira kwa olamulira Kufunika kolemba piritsi la ibrutinib pansi pamikhalidwe yofanana ndi kapisozi yomwe yalembedwa kale. |
| Mndandanda watsopano (kutumiza kochepa) | Mogamulizumab (Kyowa Kirin) | Cutaneous T-cell lymphoma (CTCL) | Kutumizanso kukapempha Gawo 100 (ndalama zogwira ntchito za chemotherapy) Ulamuliro Wofunikira kwa odwala omwe adayambiranso kapena osamva CTCL omwe adalandirapo chithandizo chimodzi choyambirira. |
Zotsatira za msonkhano wa PBAC
July 2020
Kutumiza kwa Lymphoma ndi CLL & Zotsatira
Julayi 2020 Zotsatira zamisonkhano ya PBAC pazopereka za lymphoma ndi CLL
| Mankhwala, wothandizira, mtundu wa kugonjera | Mtundu wa mankhwala kapena ntchito | Mndandanda womwe wafunsidwa ndi wothandizira / cholinga chopereka | Zotsatira za PMAC |
Kutsegula (AbbVie) Kusintha kwa ndandanda (zopereka zazing'ono) | Matenda a m'magazi a lymphocytic (CLL) | Kutumizanso kuti mupemphe Mndandanda Wofunika Wolamulira, kuphatikiza ndi Obinutuzumab, chithandizo choyambirira cha odwala omwe ali ndi CLL omwe amakhala ndi mikhalidwe yokhazikika ya fludarabine based chemotherapy. | Bungwe la PBAC linalimbikitsa kulembedwa kwa venetoclax pamodzi ndi obinutuzumab kwa odwala omwe ali ndi CLL omwe ali ndi mikhalidwe yomwe amakhalapo ndipo ndi osayenera ku fludarabine based chemo- immunotherapy. |
| Acalabrutinib (AstraZeneca) | Chronic lymphocytic leukemia (CLL) kapena lymphocytic lymphoma (SLL) | Kupempha Ulamuliro Wofunikira pamndandanda wochizira odwala (mwina ngati monotherapy kapena kuphatikiza obinutuzumab) omwe anali ndi CLL kapena SLL omwe sanalandireko omwe adawonedwa kuti ndi osayenera kulandira chithandizo ndi analogue ya purine. Pempho lachiwiri linali loti ligwiritsidwe ntchito m'gulu la odwala omwe ali ndi kuchotsedwa kwa 17p. | PBAC sinatero amalangiza kulembedwa kwa acalabrutinib, kuti agwiritsidwe ntchito ngati monotherapy kapena kuphatikiza ndi obinutuzumab, kwa odwala omwe ali ndi CLL kapena SLL omwe amawonedwa kuti ndi osayenera kulandira chithandizo ndi analogue ya purine. PBAC idawona kuti chiwongola dzanja chokwera kwambiri komanso chosatsimikizika pamtengo womwe waperekedwa. |
Mogamulizumab (Kyowa Kirin) | Cutaneous T-cell lymphoma (CTCL) | Kufunsira mndandanda wa Gawo 100 (Kupereka Ndalama Zokwanira kwa Chemotherapy) Ulamuliro Wofunika (Wolembedwa) kwa odwala omwe ayambiranso kapena osamva CTCL omwe adalandirapo chithandizo chimodzi choyambirira. | PBAC sinavomereze kulembedwa kwa mogamulizumab pochiza odwala omwe abwerera m'mbuyo kapena osamva CTCL kutsatira chithandizo chimodzi choyambirira cha matendawa. PBAC idawona kuti kuchuluka kwa phindu la mogamulizumab ponena za kupulumuka kwaufulu ndi kupulumuka kwathunthu kunali kosatsimikizika. Kuphatikiza apo, PBAC idawona kuti chiwongola dzanja chochulukirachulukiracho chinali chokwera mosavomerezeka komanso chosatsimikizika pamtengo womwe waperekedwawo, komanso kukhudzidwa kwachuma kunali kosatsimikizika. |
Marichi 2020 Msonkhano wa PBAC wa lymphoma/CLL & kuyembekezera kuchitapo kanthu kuyambira Novembala 2019
| Dzina la mankhwala ndi wothandizira | Subtype | Kulemba kofunsidwa ndi cholinga | Zotsatira za PBAC |
| Ibrutinib (Janssen) | Chronic lymphocytic leukemia (CLL) kapena lymphocytic lymphoma (SLL) | Kutumizanso kupempha kubwezeredwa kwa PBS pochiza CLL kapena SLL ndi umboni wa kuchotsedwa kwa 17p chromosome imodzi kapena zingapo. | PBAC idalimbikitsa mndandanda wa PBS wa ibrutinib pamankhwala oyamba ndi CLL/SLL ndikuchotsa 17p -tikuyembekezerabe kulembedwa, kuyambira Novembala 2019 |
| Acalabrutinib (AstraZeneca) | Chronic lymphocytic leukemia (CLL) kapena lymphocytic lymphoma (SLL) | Kufunsira mndandanda wa PBS wochizira odwala omwe abwereranso kapena osasintha CLL kapena SLL osayenera kulandira chithandizo ndi analogue ya purine. | PBAC idalimbikitsa kulembedwa kwa acalabrutinib pochiza odwala omwe ali ndi R/R CLL/SLL pamzere wachiwiri wa chithandizo - kuyembekezera kulembedwa PBS kuyambira Marichi 2020 |
| Pembrolizumab (MSD) | Primary mediastinal B-cell lymphoma (PMBCL) | Kutumizanso kuti mupemphe mndandanda wa PBS wochizira PMBCL yobwerera m'mbuyo kapena yosasinthika | PBAC idalimbikitsa mndandanda wa PBS wa pembrolizumab wa R/R PMBCL - wikuyembekezeka kulembedwa PBS kuyambira Marichi 2020 |
