Anaplastic Large Cell Lymphoma
(ALCL): Systemic-Type and Primary Cutaneous-Type
ALCL Anaplastic refers to the
appearance of the lymphoma cells, which look quite different from normal
lymphocytes. ALCL can occur in two different forms:
Occurring throughout the body -
Occurring in the skin only - primary
ALCL is an aggressive lymphoma,
whereas the primary cutaneous type follows a more indolent course.
Patients with ALCL are typically aged
in their thirties and approximately 70% are male.
What are the symptoms?
ALCL systemic - type has enlarged
lymph nodes, as well as involvement of other organs. Systemic symptoms and
elevated levels of the enzyme lactate dehydrogenase (LDH) occur in
approximately 50% of people. Bone marrow and the gastrointestinal tract are
rarely involved, but skin involvement is common.
For more information download our ALCL fact sheet here