Isishwankathelo seLymphoma eGuquliweyo (TL)
Utshintsho lwe-lymphoma lwenzeka xa i-indolent lymphoma yakho itshintsha, kwaye ibe yi-lymphoma enobudlova eneempawu ze-subtype ye-lymphoma. Oku kwahlukile kwi-indolent lymphoma yakho "ukuvuka" okanye ukusebenza ngakumbi kwaye ufuna unyango. Kwezinye iimeko, unokuba neeseli ze-lymphoma ezingenasiphelo kunye nobudlova njengoko i-lymphoma ihamba kwinkqubo yokuguqula.
I-Indolent lymphomas ngokuqhelekileyo yenziwe ngeeseli ezincinci, ezikhula ngokukhawuleza. Nangona kunjalo, ukuba ezininzi zezi seli ziqala ukukhula, kwaye ngokukhawuleza, i-lymphoma iqala ukwenza njenge-lymphoma enobudlova njenge-Diffuse Large B-cell Lymphoma (DLBCL). Akuqhelekanga xa une-lymphoma etshintshileyo, ukuba ube neeseli ze-lymphoma ezixubekileyo, ezinye zingenzi nto kwaye ezinye zinobudlova.
Iinjongo zonyango lwe-lymphoma yakho engenamsebenzi okanye etshintshileyo
Uninzi lwe-lymphomas indolent luya kuhamba ngezigaba apho abalala khona kwaye bavuke. Nangona kunjalo, ukuba i-indolent lymphoma yakho iyasebenza ngakumbi kwaye idinga unyango, uya kuba nonyango olujoliswe ekulawuleni i-lymphoma yakho engenamsebenzi.
Nangona kunjalo, ukuba i-indolent lymphoma yakho Utshintsho kwi-subtype ye-lymphoma enobudlova, uya kuba nonyango olujoliswe ekuphiliseni, okanye ukubeka i-lymphoma eyingozi ekuxoxweni.
Kutheni inguqu isenzeka?
I-Lymphoma inokutshintsha xa iiseli ze-lymphoma, okanye iijini ezibonelela ngemiyalelo kwiiseli zakho zivelisa utshintsho olutsha lwemfuzo. Olu tshintsho lutsha lunokuba sisiphumo sonyango lwangaphambili oluchasene nomhlaza, okanye lunokwenzeka ngaphandle kwesizathu esaziwayo. Utshintsho lwezofuzo lunokutshintsha indlela i-lymphoma ekhula ngayo kwaye iziphathe ngayo, okubangela ukuba kubekho ubundlongondlongo.
Ngubani ochatshazelwa yiTransformed Lymphoma?
Nabani na one-low-grade lymphoma okanye i-indolent lymphoma usengozini yokuguqulwa. Nangona kunjalo kunqabile kakhulu, kwaye kwenzeka kuphela kubantu aba-1 ukuya kwaba-3 kwi-100 nganye abane-lymphoma engenzi lutho ngonyaka ngamnye (1-3%).
Uya kuba nomngcipheko ongaphezulu kancinci wenguqu ukuba unayo isifo esikhulu (i-tumor enkulu okanye i-tumors) xa ufunyaniswa okokuqala ukuba une-lymphoma yakho engenamsebenzi.
I-lymphomas i-indolent eqhelekileyo inokuguqula iquka i-B-cell lymphoma efana nale:
- I-Lymphoma yesifo
- I-Chronic Lymphocytic Leukemia okanye iLymphoma yeSeli encinci
- I-Lymphoma yoMmandla oMda
- INodular Lymphocyte Predominant B-cell Lymphoma (eyayibizwa ngokuba yiNodular Lymphocyte Predominant Hodgkin Lymphoma)
- IMantle Cell Lymphoma engasebenziyo
- IWaldenstrom's Macroglobulinemia
Kubalulekile ukuqonda ukuba abantu abaninzi abanezi lymphoma abaguquki.
Abanye abantu abane-indolent T-cell lymphoma banokuba noguquko, kodwa ezi zinqabile.
Kunini apho inguqu ilindeleke ukuba yenzeke?
I-lymphoma eguquliweyo ingenzeka nangaliphi na ixesha, kodwa kunokwenzeka ukuba ube nenguqu malunga neminyaka emi-3-6 emva kokuba ufumene ukuba une-lymphoma yakho engapheliyo.
Umngcipheko wenguqu uyancipha kakhulu emva kokuhlala kunye ne-lymphoma yakho ye-indolent iminyaka eyi-15, kunye neenguqu emva kweli xesha zinqabile kakhulu.
iimpawu Oko kunokubonisa ukuba i-lymphoma yakho itshintshile
Unokufumana kwakhona iimpawu ze-B njengoko i-lymphoma yakho iqala ukusebenza okanye iqala ukuguquka
Zeziphi ezona nguqu zixhaphakileyo?
Ezinye iinguqu zixhaphake kakhulu kunezinye. Apha ngezantsi sidwelisa ezona ziqhelekileyo (nangona zinqabile) iinguqu ezinokuthi zenzeke.
I-lymphoma engapheliyo |
Inokutshintsha ibe yi-lymphoma elandelayo |
| I-Chronic Lymphocytic Leukemia/iLymphocytic Lymphoma encinci (CLL/SLL) |
Uguqulo ukuya kwi-Large B-cell Lymphoma (DLBCL) - olu tshintsho lubizwa ngokuba yi-Richter syndrome. Kunqabile kakhulu, i-CLL/SLL inokutshintsha ibe yi-classical subtype ye-Hodgkin Lymphoma. |
| I-Lymphoma yesifo |
Eyona nguqu ixhaphakileyo kukusasaza i-Large B-cell Lymphoma (DLBCL). Ngokunqabileyo, inokutshintsha ibe yi-B-cell lymphoma enobundlobongela, eneempawu ze-DLBCL kunye neBurkitt Lymphoma. |
| I-Lymphoplasmacytic Lymphoma (ekwabizwa ngokuba yi-Waldenstrom's macroglobulinemia) | Ukusasaza i-B-cell Lymphoma enkulu (DLBCL). |
| Mantle Cell Lymphoma (MCL) | I-Blastic (okanye i-blastoid) i-MCL. |
| Umda weLymphomas (MZL) | Ukusasaza i-B-cell Lymphoma enkulu (DLBCL). |
| I-Mucosa-Associated Lymphoid Tissue Lymphoma (MALT), i-subtype ye-MZL | Ukusasaza i-B-cell Lymphoma enkulu (DLBCL). |
| I-Nodular Lymphocyte-Predominant B-cell Lymphoma (eyayibizwa ngokuba yiNodular Lymphocyte-Predominant Hodgkin lymphoma) | Ukusasaza Enkulu ye-B-cell Lmphoma (DLBCL). |
| I-Cutaneous T-cell Lymphoma (CTCL) | Iseli Enkulu Lymphoma. |
Ukuxilongwa kunye nokubekwa kweLymphoma eTshintshiweyo
Ukuba ugqirha wakho ukrokrela ukuba i-lymphoma yakho itshintshile baya kufuna ukwenza iimvavanyo ezininzi kunye nezikena. Uvavanyo luya kubandakanya i-biopsies ukujonga ukuba iiseli ze-lymphoma zenze utshintsho olutsha, kwaye ukuba ngoku ziziphatha njenge-subtype ye-lymphoma, kwaye izikena ziya kuba kwinqanaba le-lymphoma.
Olu vavanyo kunye nezikena ziya kufana nezo wawunazo xa wawufunyaniswa ukuba une-lymphoma. Ulwazi oluvela kwezi luya kunika ugqirha wakho ulwazi olufunekayo ukukunika olona hlobo lonyango lutshintshileyo lwe-lymphoma yakho.
impatho
Nje ukuba zonke iziphumo zakho ezivela kwi-biopsy kunye nezikena zesiteji zigqityiwe, ugqirha wakho uya kuziphonononga ukuze agqibe ngolona nyango lungcono kuwe. Ugqirha wakho usenokudibana neqela lezinye iingcali ukuze axoxe ngonyango olululo kwaye oku kubizwa ngokuba yi-a iqela lezinto ezininzi (MDT) intlanganiso.
Ugqirha wakho uya kuqwalasela izinto ezininzi malunga ne-lymphoma kunye nempilo yakho jikelele ukugqiba ukuba, kwaye yintoni unyango olufunekayo. Ezinye zezinto abaza kuziqwalasela ziquka:
- Loluphi utshintsho olwenzekileyo (uhlobo lwakho olutsha lwe-lymphoma)
- Inqanaba le-lymphoma
- Naziphi na iimpawu ozifumanayo
- Indlela i-lymphoma echaphazela ngayo umzimba wakho
- Iminyaka yakho
- Naziphi na ezinye iingxaki zonyango onazo okanye amayeza owathathayo
- Ukhetho lwakho xa ulufumene lonke ulwazi oludingayo.
Iintlobo zonyango
I-lymphoma eguqulwayo kufuneka iphathwe ngendlela efanayo ne-lymphoma enobudlova. Unyango lungabandakanya:
- I-chemotherapy edibeneyo
- Umzimba womntu ongena emzimbeni
- Ukufakelwa ngokutsha kweseli ye-Autologous (ukuba usempilweni ngokwaneleyo)
- Radiotherapy (ngesiqhelo ngechemotherapy)
- Unyango lwe-CAR T-cell (I-Chimeric antigen receptor T-cell therapy - emva kwe-2 yangaphambili yonyango)
- immunotherapy
- Unyango ekujoliswe kulo
- Ukuthatha inxaxheba kulingo lwezonyango
Ukuxilongwa kweLymphoma eTshintsho (TL)
Uninzi lwe-lymphomas enobudlova inokunyangwa, okanye ibe namaxesha amade oxolelo emva konyango. Ngaloo ndlela, kukho ithemba lokuba xa unikwa unyango unokunyangwa, okanye ube noxolelo oluhlala luhleli kwi-lymphoma eyingozi ngakumbi, eguqulweyo. Nangona kunjalo, uya kufuna ulandelelo olusondeleyo emva konyango lwakho ukujonga iimpawu zokuphinda ubuyele.
I-lymphomas engapheliyo kwiimeko ezininzi ayinakunyangwa, ngoko ke nasemva kokuba unyango lwe-lymphoma yakho etshintshileyo, usenokuba neeseli ze-lymphoma ezishiyekileyo, kwaye ugqirha wakho uya kufuna ukujonga oku.
Buza ugqirha wakho ukuba ngawaphi amathuba okuba uphiliswe, ungene ekuxolelweni kwaye usahlala ne-lymphoma engenamsebenzi emva kokuba unyango lwe-lymphoma yakho etshintshileyo.
isishwankathelo
- Ukuguqulwa kwe-lymphoma kunqabile kakhulu, kuphela malunga ne-1-3 kubantu be-100 abane-lymphoma engasebenziyo abanokuguqulwa ngonyaka.
- Ukuguqulwa kuxhaphake kakhulu kubantu abane-B-cell lymphoma engenzi lutho, kodwa kunokwenzeka kubantu abane-T-cell lymphoma engenzi lutho.
- Utshintsho luxhaphake kakhulu kwiminyaka emi-3-6 emva kokuba kufunyaniswe ukuba une-lymphoma engenamsebenzi, kwaye inqabile kakhulu emva kweminyaka eyi-15.
- I-Lymphoma eguquliweyo inokwenzeka ukuba i-genes yakho okanye iiseli ze-lymphoma zihlakulela utshintsho olutsha, ukutshintsha indlela i-lymphoma ekhula ngayo kwaye iziphathe ngayo.
- I-Lymphoma eguqukileyo yahlukile kwi-lymphoma engenzi lutho "evuka" kwaye isebenze ngakumbi.
- Kusekho ukunyangwa kwi-lymphoma eguquguqukayo ngakumbi, kodwa unokuqhubeka uhlala ne-lymphoma engenamsebenzi emva kokunyanga.
- Unyango lwe-lymphoma etshintshileyo luya kujoliswa ekuphiliseni, okanye ukubeka i-lymphoma enobudlova ekuxolelweni.
- Xela zonke izinto ezintsha nezimbi iimpawu, kubandakanya B-impawu kugqirha wakho.
