Inqanaba le-lymphoma lijonga ukuba ungakanani umzimba wakho ochatshazelwa yi-lymphoma, kwaye unikezela ngolwazi malunga nokuba zeziphi iindidi zonyango oluya kuba lulo.
Kuthetha ukuthini ukwenziwa kweqonga?
Inqanaba libhekisa kubungakanani bomzimba wakho ochatshazelwa yi-lymphoma yakho - okanye ukuba isasazeke kangakanani na ukusuka apho iqale khona.
I-Lymphocytes inokuhamba kuyo nayiphi na indawo yomzimba wakho. Oku kuthetha ukuba iiseli ze-lymphoma (i-lymphocyte ezinomhlaza), zinokuhamba nazo nakweliphi na ilungu lomzimba wakho. Kuya kufuneka ukuba wenze iimvavanyo ezininzi ukuze ufumane olu lwazi. Ezi mvavanyo zibizwa ngokuba zii-staging tests kwaye xa ufumana iziphumo, uya kufumanisa ukuba unenqanaba lokuqala (I), inqanaba lesibini (II), inqanaba lesithathu (III) okanye inqanaba lesine (IV) lymphoma.
I-Staging Lymphoma - I-Ann Arbor okanye i-Lugano Staging System
Inqanaba lakho le-lymphoma liya kuxhomekeka kwi:
- Zingaphi iindawo zomzimba wakho ezine-lymphoma
- Apho i-lymphoma ibandakanya ukuba ingaphezulu, ngaphantsi okanye kumacala omabini e-diaphragm yakho (umsipha omkhulu, owenziwe ngedome phantsi kwembambo yakho eyahlula isifuba sakho kwisisu sakho)
- Ingaba i-lymphoma isasazeke kumathambo akho okanye ezinye izitho ezifana nesibindi sakho, imiphunga, ulusu okanye ithambo.
Inqanaba I no-II libizwa ngokuba 'linqanaba lokuqala okanye elilinganiselweyo' (elibandakanya indawo elinganiselweyo yomzimba wakho).
Amanqanaba III kunye ne-IV abizwa ngokuba 'yinqanaba eliphambili' (lixhaphake kakhulu). Kubalulekile ukwazi ukuba ngokungafaniyo nezinye ii-cancer, ezininzi ze-lymphoma ezinobundlobongela ziyakwazi ukuphiliswa. Thetha nogqirha wakho malunga namathuba akho okunyangwa okanye uxolelo lwexesha elide.
Isigaba 1 | Enye indawo ye-lymph node iyachaphazeleka, nokuba ngaphezulu okanye ngaphantsi kwe-diaphragm*. |
Isigaba 2 | Iindawo ezimbini okanye ngaphezulu ze-lymph node zichaphazeleka kwicala elinye le-diaphragm*. |
Isigaba 3 | Ubuncinci indawo ye-lymph node ngaphezulu kunye nommandla we-lymph node enye ngaphantsi kwe-diaphragm* iyachaphazeleka. |
Isigaba 4 | I-Lymphoma ikwii-lymph nodes ezininzi kwaye isasazeke kwamanye amalungu omzimba (umz. amathambo, imiphunga, isibindi). |
Ulwazi olongezelelweyo lweqonga
Ugqirha wakho usenokuthetha ngenqanaba lakho esebenzisa unobumba, njengo-A, B, E, X okanye S. Ezi leta zinika ulwazi oluthe kratya malunga neempawu onazo okanye indlela umzimba wakho ochatshazelwa ngayo yi-lymphoma. Lonke olu lwazi lunceda ugqirha wakho akufumanele esona sicwangciso sonyango.
ileta | meaning | ukubaluleka |
A okanye B |
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E & X |
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S |
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(Udakada lwethu lilungu lethu Inkqubo ye-lymphatic ehluza kwaye icoce igazi lethu, kwaye yindawo yethu yokuphumla iiseli ze-B kwaye zenze izilwa-buhlungu) |
Uvavanyo lweqonga
Ukufumanisa ukuba leliphi inqanaba onalo, unokucelwa ukuba wenze ezinye zezi mvavanyo zilandelayo:
Icwecwe le-compact tomography (CT)
Ezi scan zithatha imifanekiso ngaphakathi esifubeni sakho, isisu okanye i-pelvis. Banika imifanekiso eneenkcukacha enika ulwazi ngakumbi kuneX-reyi eqhelekileyo.
I-Positron emission tomography (PET) scan
Esi siskena esithatha imifanekiso yangaphakathi emzimbeni wakho wonke. Uyakunikwa kunye nenaliti kunye nelinye iyeza elifunxa iiseli ezinomhlaza - ezinjengeeseli ze-lymphoma. Iyeza elinceda i-PET scan ukuchonga apho i-lymphoma iphi kunye nobukhulu kunye nokumila ngokugqamisa iindawo ezineeseli ze-lymphoma. Ezi ndawo ngamanye amaxesha zibizwa ngokuba "zishushu".
Ukugqobhoza iLumbar
I-lumbar puncture yinkqubo eyenziwa ukujonga ukuba unayo nayiphi na i-lymphoma kwindawo yakho Inkqubo ye-nervous central (CNS), equka ingqondo yakho, intambo yomgogodla kunye nommandla ojikeleze amehlo akho. Kuya kufuneka uhlale uthe cwaka kakhulu ngexesha lenkqubo, ukuze iintsana kunye nabantwana bafumane isibulali-ntlungu jikelele ukuze balalise okwethutyana xa inkqubo isenziwa. Uninzi lwabantu abadala luya kufuna kuphela iyeza lokuthomalalisa lendawo ukulungiselela inkqubo yokwenza indawo leyo.
Ugqirha wakho uyakukufaka inaliti emqolo, kwaye akhuphe incindi encinci ebizwa ngokuba “.ulwelo lomgogodla wengqondo” (CSF) ukusuka ngeenxa zonke kwintambo yakho yomgogodla. I-CSF lulwelo olusebenza kancinane njengento efunxa ukothuka kwi-CNS yakho. Ikwathwala iiprotheyini ezahlukeneyo kunye nosulelo olulwa neeseli zokhuselo lomzimba ezifana ne-lymphocytes ukukhusela ingqondo yakho kunye nentambo yomgogodla. I-CSF inokunceda nokukhupha naluphi na ulwelo olongezelelweyo onokuba nalo engqondweni yakho okanye ujikeleze umnqonqo wakho ukuthintela ukudumba kwezo ndawo.
Isampulu ye-CSF emva koko iya kuthunyelwa kwi-pathology kwaye ihlolwe naziphi na iimpawu ze-lymphoma.
Umongo wethambo
- I-Bone marrow aspirate (BMA): olu vavanyo luthatha inani elincinci lolwelo olufumaneka kwisithuba somongo wethambo.
- Umongo wethambo aspirate trephine (BMAT): olu vavanyo luthatha isampulu encinci yomongo wethambo.
Iisampuli ke zithunyelwa kwi-pathology apho zikhangelwa iimpawu ze-lymphoma.
Inkqubo ye-biopsies yomongo wethambo inokwahluka ngokuxhomekeke kwindawo ofumana kuyo unyango lwakho, kodwa iya kubandakanya i-anesthetic yasekhaya ukwenza ndindisholo indawo.
Kwezinye izibhedlele, unokunikwa i-sedation elula ekunceda ukuba uphumle kwaye inokukuyekisa ukukhumbula inkqubo. Nangona kunjalo abantu abaninzi abayifuni le nto kwaye endaweni yoko banokuba “nempempe eluhlaza” yokumunca. Le mpempe eluhlaza ineyeza elibulala iintlungu kulo (elibizwa ngokuba yiPenthrox okanye i-methoxyflurane), olisebenzisayo njengoko kufuneka kulo lonke inkqubo.
Qinisekisa ukuba ubuze ugqirha wakho ukuba yintoni ekhoyo ukuze ukhululeke ngakumbi ngexesha lenkqubo, kwaye uthethe nabo malunga nento ocinga ukuba iya kuba yinto efanelekileyo kuwe.
Olunye ulwazi malunga ne-biopsy yomongo wethambo inokufumaneka kwiphepha lethu lewebhu apha.
Ukumiswa kwe-CLL - Inkqubo ye-RAI yokubonisa
Ukuhlelwa kwe-CLL kwahluke kancinane kunezinye iindidi ze-lymphoma, kuba i-CLL iqala egazini kunye nomongo wethambo.
Inkqubo ye-RAI iya kujonga kwi-CLL yakho ukubona ukuba uyayenza na, okanye awunayo nanye kwezi zilandelayo:
- amanqanaba aphezulu e-lymphocytes egazini lakho okanye umongo wethambo - oku kubizwa ngokuba yi-lymphocytosis (lim-foe-cy-toe-sis)
- ukudumba kwe-lymph nodes - lymphadenopathy (limf-a-den-op-ah-thee)
- udakada olwandisiweyo – i<em>splenomegaly (i-splen-oh-meg-ah-lee)
- Amanqanaba aphantsi eeseli ezibomvu zegazi egazini lakho-i-anemia (a-nee-mee-yah)
- amanqanaba asezantsi eplatelet egazini lakho – thrombocytopenia (throm-bow-cy-toe-pee-nee-yah)
- isibindi esandisiweyo – hepatomegaly (hep-at-o-meg-a-lee)
Sithetha ntoni isigaba ngasinye seRAI
| Inqanaba le-RAI 0 | I-Lymphocytosis kwaye akukho kwandiswa kwee-lymph nodes, i-spleen, okanye isibindi, kunye neeseli zegazi ezibomvu eziqhelekileyo kunye nezibalo zeplatelet. |
| Inqanaba le-RAI 1 | I-Lymphocytosis kunye ne-lymph nodes eyandisiweyo. Udakada nesibindi azondiswanga kwaye iseli ebomvu yegazi kunye nezibalo zeplatelet ziqhelekile okanye ziphantsi kancinci. |
| Inqanaba le-RAI 2 | I-Lymphocytosis kunye ne-spleen eyandisiweyo (kwaye mhlawumbi nesibindi esandisiweyo), kunye okanye ngaphandle kwee-lymph nodes. Iseli ebomvu yegazi kunye nezibalo zeplatelet ziqhelekile okanye ziphantsi kancinci |
| Inqanaba le-RAI 3 | I-Lymphocytosis kunye ne-anemia (iiseli ezibomvu zegazi ezimbalwa kakhulu), kunye okanye ngaphandle kwe-lymph nodes, i-spleen, okanye isibindi. Ubalo lwePlatelet lusondele kwisiqhelo. |
| Inqanaba le-RAI 4 | I-Lymphocytosis kunye ne-thrombocytopenia (iiplatelets ezimbalwa kakhulu), kunye okanye ngaphandle kwe-anemia, i-lymph nodes eyandisiweyo, i-spleen, okanye isibindi. |
*I-Lymphocytosis ithetha i-lymphocyte ezininzi kakhulu egazini lakho okanye umongo wethambo
UHlelo lweKlinikhi lweLymphoma
Iiseli zakho ze-lymphoma zinepateni eyahlukileyo yokukhula, kwaye zibukeka ngokwahlukileyo kwiiseli eziqhelekileyo. Ibakala le-lymphoma yakho yindlela ekhula ngayo ngokukhawuleza iiseli zakho ze-lymphoma, ezichaphazela indlela yokujonga phantsi kwe-microscope. Amabanga ngamaBakala 1-4 (asezantsi, aphakathi, aphezulu). Ukuba unenqanaba eliphezulu le-lymphoma, iiseli zakho ze-lymphoma ziya kubonakala zihluke kakhulu kwiiseli eziqhelekileyo, kuba zikhula ngokukhawuleza ukuba ziphuhlise ngokufanelekileyo. Isishwankathelo samabanga singezantsi.
- I-G1 - ibakala eliphantsi - iiseli zakho zijongeka kufutshane nesiqhelo, kwaye zikhula kwaye zisasazeka kancinci.
- I-G2 - ibakala eliphakathi - iiseli zakho ziqala ukubonakala ngokwahlukileyo kodwa ezinye iiseli eziqhelekileyo zikhona, kwaye ziyakhula kwaye zisasazeke ngesantya esiphakathi.
- I-G3 - ibakala eliphezulu - iiseli zakho zikhangeleka ngokwahlukileyo ngeeseli ezimbalwa eziqhelekileyo, kwaye zikhula kwaye zisasazeka ngokukhawuleza.
- I-G4 - ibakala eliphezulu - iiseli zakho zikhangeleka zahluke kakhulu kwisiqhelo, kwaye zikhula kwaye zisasazeke ngokukhawuleza.
Lonke olu lwazi longeza kumfanekiso uphela owakha ugqirha wakho ukuze akuncede ugqibe ngolona hlobo lulungileyo lonyango lwakho.
Kubalulekile ukuba uthethe nogqirha wakho malunga neemeko zakho zomngcipheko ukuze ube nombono ocacileyo wokuba ulindele ntoni kunyango lwakho.
