Leli khasi lizochaza amagama avamile noma ama-akhronimi (amagama afushaniswe abe yizinhlamvu ezimbalwa ezifana ne-PICC, ABVD, NHL njll), ukuze uzizwe uqiniseka ngokwengeziwe lapho ukhuluma namaqembu akho okunakekelwa kwezempilo, abangani nomndeni mayelana nohambo lwakho lwe-lymphoma noma i-CLL.
Njengoba uqhubeka, uzobona ezinye izincazelo zinamagama aluhlaza okwesibhakabhaka futhi adwetshelwe. Uma uchofoza lezi, uzokwazi ukuthola ulwazi olwengeziwe ngalezo zihloko. Izixhumanisi zemithetho yokwelapha zifakiwe, kodwa uma uthola ukwelashwa kwakho kungafakiwe ohlwini, sicela uxhumane nathi. Ngaphandle kwalokho, ungabheka ukuthi iphrothokholi yakho ivaliwe yini Ikhasi lokwelashwa kwe-anticancer eviQ.
A
esiswini – ingxenye emaphakathi yengaphambili lomzimba wakho, phakathi kwesifuba sakho nesinqe (amathambo azungeze inqulu yakho), ngokuvamile ebizwa ngokuthi isisu.
I-ABVD – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe, bheka:
Okumnandi - ukugula noma uphawu olukhula ngokushesha kodwa oluhlala isikhashana nje.
Ukwelashwa kwe-Adjuvant -okunye ukwelashwa okunikezwa ukukhulisa ukusebenza kahle kokwelashwa okuyinhloko.
Isigaba esithuthukile - i-lymphoma esabalele - ngokuvamile isigaba sesi-3 (i-lymphoma ezinhlangothini zombili ze-diaphragm) noma isigaba sesi-4 (i-lymphoma esisabalele ezithweni zomzimba ezingaphandle kwesistimu yakho ye-lymphatic). Uhlelo lwe-lymphatic lugcwele umzimba wonke, ngakho-ke kuvamile ukuba ne-lymphoma ethuthukisiwe lapho itholakala okokuqala. Abantu abaningi abane-lymphoma ethuthukisiwe bangelapheka.
I-Aetiology (“EE-tee-oh-luh-jee”) – imbangela yesifo
Unolaka - igama elisetshenziselwa ukuchaza i-lymphoma ekhula ngokushesha. Ama-lymphomas amaningi anolaka asabela kahle ekwelashweni futhi abantu abaningi abane-lymphoma enolaka bangelapheka.
AIDS - i-immune deficiency syndrome etholakalayo. Isifo esidalwa yigciwane lesandulela ngculazi (human immunodeficiency virus) lapho amasosha akho omzimba engakwazi ukulwa nezifo.
Umdlavuza ochaza i-AIDS - uma une-HIV futhi uba nemidlavuza ethile, kutholakala ukuthi une-AIDS.
I-AITL – uhlobo lwe-T-cell non-Hodgkin lymphoma olubizwa ngokuthi I-Angioimmunoblastic T-cell Lymphoma.
I-ALCL – uhlobo lwe-non-Hodgkin lymphoma olubizwa ngokuthi I-Anaplastic Large Cell lymphoma. Kungaba yisistimu (noma yikuphi emzimbeni wakho) noma i-cutaneous (ithinta kakhulu isikhumba sakho). Kukhona futhi uhlobo oluncane olungavamile olubizwa ngokuthi i-breast implant ehambisana ne-ALCL ethinta abantu abafake amabele.
Ikhadi lesexwayiso - a ikhadi elinolwazi olubalulekile lwanoma ubani okwelaphayo esimweni esiphuthumayo. Uma unekhadi lesexwayiso nganoma yisiphi isizathu, kufanele uhlale uliphethe.
Ama-alkylating agents - uhlobo lokwelapha ngamakhemikhali noma omunye umuthi ovimba ukukhula kwamangqamuzana, ngokuvamile asetshenziselwa ukwelapha umdlavuza. Izibonelo yi-chlorambucil ne-cyclophosphamide.
Allo - bheka i-allogenieic.
I-Allogeneic (“ALLO-jen-AY-ik”) – ichaza ukufakelwa kwezicubu ezinikelwe zisuka komunye umuntu, ngezinye izikhathi ezaziwa ngokuthi 'i-allograft' noma 'ukufakelwa komnikeli'. Isibonelo yi-allogeneic ukufakelwa kwe-stem cell.
I-Alopecia - igama lezokwelapha lapho izinwele zakho ziqothuka. Kungenzeka njenge-side effect ye-chemotherapy.
I-anemia - amazinga aphansi e-hemoglobin (Hb) egazini lakho (equkethwe kumangqamuzana abomvu egazi). I-Hemoglobin ithwala umoya-mpilo emzimbeni wakho.
Ukubulala izinzwa – umuthi onikezwa ukuthuntubeza ingxenye ethile yomzimba wakho (i-anesthesia yendawo) noma yokulalisa umzimba wakho wonke (i-anesthesia jikelele).
I-Analgesic – okuthile (njengomuthi) osusa noma onciphisa ubuhlungu.
I-anorexia – uma ungakuthandi ukudla – uphelelwa yisifiso sokudla, ikakhulukazi ngenxa yesifo noma ukwelashwa kwaso. Lokhu kuhlukile ku-anorexia nervosa, okuwukuphazamiseka kwemikhuba yokudla.
Ama-Anthracyclines - Imithi yokwelapha ngamakhemikhali ephazamisa ukwakheka kwe-DNA yamaseli, iwavimbela ekwenzeni amaseli amaningi. Izibonelo yi-doxorubicin (Adriamycin®) kanye ne-mitoxantrone.
Umuntu - a amaprotheni enziwe ama-B-cell avuthiwe (abizwa ngokuthi ama-Plasma cell) aqaphela futhi anamathele ezintweni okungezona ezasemzimbeni wakho, njengamagciwane, amagciwane noma amanye amangqamuzana omdlavuza. Ibe ixwayisa amanye amaseli omzimba wakho ukuthi adinga ukuza futhi alwe. Amasosha omzimba abizwa nangokuthi ama-immunoglobulins (Ig).
I-antibody-conjugate yezidakamizwa - ukwelashwa kusetshenziswa i-monoclonal antibody ehlanganiswe ne-chemotherapy engaletha i-chemotherapy ngqo kuseli le-lymphoma eliqondiwe.
I-antiemetic (“AN-tee-em-ET-ik”) – umuthi ongakusiza ukuvimba ukugula nokuhlanza (ukugula).
I-antigen - ingxenye yento 'yangaphandle' ebonwa amasosha omzimba. Lokhu bese kubangela ukuthi amasosha akho omzimba akhiqize amasosha omzimba ukulwa nezinto zangaphandle (njengegciwane, amagciwane, noma esinye isifo).
Ama-Antimetabolites - a iqembu lemithi yokwelapha ngamakhemikhali ehlangana ne-DNA yeseli futhi iyivimbele ekuhlukaneni; izibonelo zifaka i-methotrexate, i-fluorouracil, i-fludarabine ne-gemcitabine.
I-Apheresis - a inqubo ehlukanisa amangqamuzana athile egazini lakho. Ithuluzi elikhethekile lihlukanisa ingxenye ethile yegazi lakho (ngokwesibonelo i-plasma, ingxenye ewuketshezi yegazi lethu, noma amaseli afana nama-stem cell) bese libuyisela kuwe lonke elinye igazi.
I-Apoptosis - inqubo evamile lapho amaseli amadala noma alimele efa khona ukuze avule isikhala samaseli amasha anempilo. Kwezinye izimo, i-apoptosis nayo ingabangelwa izidakamizwa ze-chemotherapy kanye ne-irradiation.
I-APS – Acute Pain Service – insizakalo etholakala kwezinye izibhedlela ukusiza ukuphatha ubuhlungu obunzima, kodwa okulindeleke ukuthi kube ngokwesikhashana.
I-Aspirate - isampula yamaseli athathwe ngokumuncwa kusetshenziswa inaliti.
ATLL - uhlobo lwe-non-Hodgkin lymphoma olubizwa ngokuthi I-T-cell leukeamia-lymphoma yabantu abadala. Kungabizwa ngokuthi: Acute, Lymphomatous, Chronic noma Smouldering.
Okuzenzakalelayo - Bona i-Autologous.
I-autologous (“aw-TAW-luh-GUS”) - ukufakelwa usebenzisa izicubu zakho (njengethambo lomnkantsha noma ama-stem cells).
B
BBB - bheka umgoqo wobuchopho begazi.
Ama-B-cell / B-lymphocyte – uhlobo lwamangqamuzana egazi amhlophe (i-immune cell) elilwa nokutheleleka ngokukhiqiza amasosha omzimba.
B izimpawu - izimpawu ezintathu ezibalulekile ze-lymphoma - imfiva, ukujuluka ebusuku nokuncipha kwesisindo okungachazeki - okungenzeka kubantu abane-lymphoma.
Ama-bacterium - izinto ezincane (ezincane), ezingadala izifo; evame ukubizwa ngokuthi 'amagciwane'. Akhona namabhaktheriya amahle, akugcina unempilo.
BEACOPP – iphrothokholi yokwelapha, nayo ngezinye izikhathi ebizwa ngokuthi i-Escalated BEACOPP. Ukuze uthole olunye ulwazi sicela umthetho olandelwayo lapha.
UBenign - hhayi umdlavuza (nakuba izigaxa ezinhle noma izimo zisengadala izinkinga uma zizinkulu noma zisendaweni ethile ezithinta indlela umzimba wakho osebenza ngayo (njengasengqondweni yakho).
Ukwelapha ngebhayoloji - imithi elwa nomdlavuza esekelwe ezintweni ezenziwa umzimba ngokwemvelo futhi ezithinta indlela ingqamuzana lomdlavuza elisebenza ngayo; izibonelo ama-interferon nama-monoclonal antibodies.
Biopsy - a isampula yethishu noma amaseli aqoqwe futhi ahlolwe ngaphansi kwesibonakhulu ukuze kubonakale ukuthi akhona yini amaseli angajwayelekile. Lokhu kungenziwa ukuze kuqinisekiswe ukuxilongwa kwakho. Kubantu abane-lymphoma, i-biopsy evame kakhulu i-lymph node biopsy (ebheka amaseli angaphansi kwe-microscope ukuze abone ukuthi hlobo luni lwe-lymphoma).
I-Biosimilar - a umuthi oklanyelwe ukucishe ufane nomuthi osuvele usetshenziswa ('umuthi oyinkomba'). Ama-Biosimilars kumele aphephe futhi asebenze kahle, kodwa angabi ngcono kunomuthi oyinkomba ezivivinyweni zomtholampilo ngaphambi kokuba zigunyazwe ukuthi zisetshenziswe.
BL – uhlobo lwe-non-Hodgkin Lymphoma olubizwa ngokuthi I-Burkitt lymphoma - Kungaba njalo:
- I-Endemic (ithinta kakhulu labo abanesizinda sase-Afrika).
- I-Sporadic (ithinta kakhulu labo abanesizinda esingesona esase-Afrika).
- I-Immunodeficiency-associated (ethinta kakhulu labo abane-HIV/AIDS noma enye i-immunodeficiency).
Iseli eliqhumayo – ingqamuzana legazi elingavuthiwe, emnkantsheni wakho. Akuvamile ukutholakala egazini lakho.
Impumputhe noma impumputhe – lapho abantu ababamba iqhaza ocwaningweni lomtholampilo bengazi ukuthi yikuphi ukwelashwa abakutholayo. Kwesinye isikhathi, udokotela wakho naye akazi - lokhu kubizwa ngokuthi uhlolo 'lwe-double-blind'. Lokhu kwenziwa ngoba ukwazi ukuthi ukuluphi uhlobo lokwelashwa kungase kube nomthelela kulokho okulindele, noma okulindelwe udokotela wakho ngokwelashwa futhi kuthinte imiphumela yohlolo.
Isithiyo segazi nobuchopho – umgoqo wamangqamuzana nemithambo yegazi evumela kuphela izinto ezithile ukuthi zifinyelele ubuchopho, zibuvikele kumakhemikhali ayingozi kanye nezifo.
Amangqamuzana egazi – izinhlobo ezintathu eziyinhloko zamangqamuzana noma izingcezu zamangqamuzana ezikhona egazini amangqamuzana abomvu, amangqamuzana amhlophe namaplatelet.
Inani legazi – isampula yegazi liyathathwa futhi izinombolo zamaseli ahlukene noma amaprotheni akhona kusampula yegazi ayahlolwa kusetshenziswa isibonakhulu futhi kuqhathaniswa 'nenani elivamile' lalawo maseli noma izinombolo zamaphrotheni ezitholakala egazini elinempilo.
BMT - ukwelashwa lapho amangqamuzana omnkantsha anempilo eqoqwa khona kumnikeli (umuntu ongeyena wena), anikezwa wona ukuze athathele indawo yamangqamuzana e-lymphoma anomdlavuza, ngemva kokuba usuthole umthamo omkhulu wokwelapha ngamakhemikhali.
Umkantsha - izicubu eziyisipontshi enkabeni yamanye amathambo amakhulu omzimba lapho amaseli egazi enziwa.
Umugqa we-Broviac® Uhlobo lomugqa ophakathi nendawo (ithubhu elithambile elithambile) elisetshenziswa ngezinye izikhathi ezinganeni. Ukuze uthole imininingwane eyengeziwe ngemigqa emaphakathi eshunquliwe sicela ubheke Ulwazi lwesiguli se-eviQ lapha.
C
Amaseli omdlavuza - amangqamuzana angavamile lawo khula futhi nande ngokushesha, futhi bangafi lapho kufanele.
Candida (“CAN-dih-dah”) -isikhunta esingabangela ukutheleleka (i-thrush), ikakhulukazi kubantu abanamasosha omzimba abuthakathaka.
ICannula (“CAN-ewe-lah”) – ishubhu elithambile eligobekayo elifakwa emthanjeni wakho ngenaliti, ukuze umuthi wakho unikezwe ngqo emithanjeni yegazi lakho (inaliti iyakhishwa futhi uzobe usele nepayipi lepulasitiki kuphela. ).
Ukwelashwa kwe-CAR T-cell - treatment esebenzisa awakho, ama-T-cells ashintshwe izakhi ukuze abone futhi abulale amaseli e-lymphoma. Ukuze uthole ulwazi olwengeziwe nge-CAR T-cell therapy sicela ubheke ikhasi lethu ku Ukuqonda ukwelashwa kwe-CAR T-cell.
I-Carcinogenic (“CAR-sin-o-jen-ik”) – into engabangela umdlavuza.
I-cardiovascular - ukwenza ngenhliziyo yakho nemithambo yegazi.
I-Catheter - a eguquguqukayo, ishubhu elingenalutho elingafakwa esithweni ukuze uketshezi noma amagesi akhishwe, noma anikezwe, emzimbeni.
I-CBCL – uhlobo lwe-non-Hodgkin lymphoma olubizwa ngokuthi I-B-cell Lymphoma yesikhumba - Izinhlobo ezincane ze-CBCL zifaka:
- I-Primary cutaneous follicle cell lymphoma.
- I-Primary cutaneous marginal zone B-cell lymphoma.
- I-cutaneous eyinhloko isakaza i-B-cell lymphoma enkulu - uhlobo lomlenze.
- I-cutaneous eyinhloko isakaza i-B-cell enkulu.
CD - Iqoqo lokuhlukanisa (kungaba i-CD20, i-CD30 CD15 noma ezinye izinombolo ezihlukene). Bona omaka bendawo yeseli.
Iseli - i-microscopic isakhiwo somzimba; zonke izitho zethu zakhiwe ngamangqamuzana futhi nakuba zinesakhiwo esiyisisekelo esifanayo, zilungiswa ngokukhethekile ukuze zakhe ingxenye ngayinye yomzimba.
Izivimba zesignali zeseli - amaseli athola izimpawu eziwagcina ephila futhi awenze ahlukane. Lawa masignali athunyelwa ngendlela eyodwa noma ngaphezulu. Izivimbeli zezimpawu zeseli ziyimithi emisha evimba isignali noma ingxenye ebalulekile yendlela. Lokhu kungenza amaseli afe noma awavimbe ekukhuleni.
Omaka bendawo yeseli - amaprotheni atholakala ebusweni bamaseli angasetshenziswa ukukhomba izinhlobo ezithile zamaseli. Alebulwe kusetshenziswa izinhlamvu nezinombolo (isibonelo i-CD4, CD20, lapho i-'CD' imele 'iqoqo lokuhlukanisa')
Umugqa omaphakathi - a ithubhu elincane eligobekayo, efakwa emthanjeni omkhulu esifubeni; ezinye izinhlobo zingashiywa endaweni izinyanga ezithile, okuvumela zonke izindlela zokwelapha ukuba zinikezwe futhi lonke ukuhlolwa kwegazi kuthathwe ngomugqa owodwa.
Isistimu yezinzwa emaphakathi (CNS) - the ubuchopho nomgogodla.
Uketshezi lwe-Cerebrospinal (CSF) – uketshezi oluzungeze izicubu zesimiso sezinzwa esimaphakathi.
Ukwelashwa ngamakhemikhali (“KEE-moh-ther-uh-pee”) – uhlobo lwemithi elwa nomdlavuza elimaza futhi ibulale amaseli akhula ngokushesha. Kwesinye isikhathi ifushaniswa ibe yi-“chemo”.
I-Chemo-immunotherapy - i-chemotherapy (isibonelo, i-CHOP) nge-immunotherapy (isibonelo, i-rituximab). Ukuqala komuthi we-immunotherapy kuvame ukungezwa esifinyezweni somuthi we-chemotherapy, njenge-R-CHOP.
cHL - I-Hodgkin Lymphoma yakudala - Izinhlobo ezingaphansi ze-cHL zifaka:
- I-Nodular Sclerosis cHL.
- I-CHL yeselula ehlanganisiwe.
- I-Lymphocyte iphelile i-CHL.
- Lymphocyte rich cHL.
CHOEP (14 noma 21) – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe, sicela ubheke okungezansi:
I-Chromosome - 'iphakheji' elincane elitholakala phakathi nendawo (nucleus) ye wonke amaseli emzimbeni equkethe iqoqo lezakhi zofuzo (amakhodi e-DNA). Zivela ngababili, eyodwa ivela kunyoko enye kubaba wakho. Abantu ngokuvamile banama-chromosome angu-46, ahlelwe ngamapheya angu-23.
Okungapheliyo - isimo, esithambile noma esinzima, esihlala isikhathi eside.
I-CHIVPP – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
I-CHOP (14 noma 21) – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke amaphrothokholi angezansi:
Ukwahlukanisa - ukuqoqwa kwezinhlobo ezifanayo zomdlavuza ndawonye, ngokusekelwe endleleni ezibukeka ngayo ngaphansi kwesibonakhulu nangemuva kokwenza izivivinyo ezikhethekile.
Uchwepheshe wabahlengikazi basemtholampilo (CNS) - I-CNS yakho ngokuvamile iyoba ngumuntu wokuqala okufanele uxhumane naye nganoma yiziphi izinkathazo noma okukukhathazayo. Umhlengikazi ogxile ekunakekeleni abantu abane-lymphoma. Bangakusiza uqonde okwengeziwe ngawe lymphoma kanye nokwelashwa kwayo.
Isivivinyo somtholampilo - ucwaningo locwaningo oluhlola izindlela zokwelapha ezintsha ukuthola ukuthi iyiphi esebenza kangcono futhi ibaphi abantu. Isibonelo, abacwaningi bangase bahlole imiphumela yokwelashwa okusha noma isici sokunakekela ngokumelene nalokho okuvamile ukwenziwa, ukuze babone ukuthi iyiphi esebenza kahle kakhulu. Akuzona zonke izifundo zocwaningo ezibandakanya ukwelashwa. Okunye kungase kugxile ekuthuthukiseni izivivinyo noma izinga lempilo yakho. Ukuze uthole ulwazi olwengeziwe ngezivivinyo zomtholampilo, sicela ubheke ezethu ukuqonda ikhasi lezivivinyo zemitholampilo lapha.
Cll - I-Chronic lymphocytic leukemia ifana kakhulu ne-lymphocytic lymphoma encane (SLL), kodwa amangqamuzana anomdlavuza atholakala kakhulu emnkantsheni nasegazini esikhundleni sesimiso se-lymphatic.
I-CMV - okufushane kwe-'cytomegalovirus'. Igciwane okungenzeka ukuthi libangele izifo kubantu abanamasosha omzimba abuthakathaka.
I-chemotherapy ehlanganisiwe - ukwelashwa ngemithi yokwelapha ngamakhemikhali engaphezu kowodwa.
I-CODOX-M – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
Ukwelashwa kwemodi ehlanganisiwe (CMT) - ukusebenzisa kokubili i-chemotherapy kanye ne-radiotherapy enkambweni eyodwa yokwelashwa kwe-anti-lymphoma.
Qedela impendulo – abukho ubufakazi be-lymphoma obusele ngemva kokwelashwa.
I-CTCL – uhlobo lwe I-Peripheral T-cell Lymphoma ebizwa ngokuthi i-Cutaneous T-cell Lymphoma.
Izinhlobo ezincane ze-CTCL zesigaba sokuqala zifaka:
- I-Mycosis Fungoides (MF).
- I-primary cutaneous anaplastic big-cell lymphoma (PCALCL).
- I-Lymphomatoid papulosis (LyP).
- I-subcutaneous panniculitis-like T-cell lymphoma (SPTCL).
Izigaba ezingaphansi kwesigaba esithuthukisiwe zihlanganisa:
- I-Sezary Syndrome (SS).
- I-Primary Cutaneous Anaplastic Large-cell Lymphoma (PCALCL).
- I-Subcutaneous Panniculitis-like T-cell Lymphoma (SPTCL).
CT scan - i-tomography yekhompyutha. Ukuskena okwenziwe emnyangweni we-X-ray ohlinzeka ngesithombe esinengqimba sangaphakathi lomzimba; ingasetshenziswa ukuthola isifo sethishu noma isitho.
Cure - ukwelapha isifo noma isimo kuze kufike lapho sesidlule khona futhi ngeke sibuye esikhathini esizayo.
Isikhumba (“umugqa-TAY-nee-us”) – okuphathelene nesikhumba sakho.
CVID - I-ImmunoDeficiency Ejwayelekile Eguquguqukayo - isimo esingathinta imizimba yakho amandla okwenza noma yiluphi uhlobo lwamasosha omzimba (ama-immunoglobulins).
I-CVP noma i-R-CVP noma i-O-CVP- izinqubo zokwelapha. Ukuze uthole imininingwane eyengeziwe chofoza izixhumanisi ezingezansi:
Umjikelezo - a block of chemotherapy (noma okunye ukwelashwa) okulandelwa isikhathi sokuphumula ukuze amangqamuzana anempilo alulame.
Cyto- ukwenza namaseli.
Ama-cytogenetics - ucwaningo nokuhlolwa kwama-chromosome kumaseli abandakanyeka esifweni sakho. Kuyasiza ukuhlonza izinhlobo ezincane ze-lymphoma futhi, ukufinyelela ekuxilongweni okunembile ukuze kusizwe ukunquma ukwelashwa okungcono kakhulu kwakho.
I-Cytokine release syndrome (CRS) - ukusabela komzimba kwezinye izinhlobo ze-immunotherapy ezibangela ukukhululwa okusheshayo kwamakhemikhali okuthiwa ama-cytokines egazini lakho. Kungabangela ukuvuvukala okukhulu emzimbeni wakho
I-Cytotoxic kunemithi noma amaphilisi (“i-sgh-toe-TOX-ik”) - imithi enobuthi (enobuthi) kumaseli. Lezi zinikezwa ukubhubhisa noma ukulawula amangqamuzana omdlavuza.
D
I-DA-R-EPOCH – umthetho olandelwayo wokwelashwa – Ukuze uthole imininingwane eyengeziwe sicela ubheke ukwelashwa protocol lapha.
Iyunithi yokunakekelwa kwasemini - ingxenye yesibhedlela yabantu abadinga ukuhlinzwa okukhethekile kodwa okungadingeki balale esibhedlela ubusuku bonke.
Isiguli sosuku noma isiguli sangaphandle - isiguli esiya esibhedlela (isibonelo, ukuze sithole ukwelashwa) kodwa esingalali ubusuku bonke.
I-DDGP - Iphrothokholi yokwelashwa. Ukuze uthole imininingwane eyengeziwe, sicela ubheke i- protocol lapha.
I-DHAC noma i-DHAP- Imithethonqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke amaphrothokholi lapha:
Sifo - ukuthola ukuthi yisiphi isimo noma isifo onaso.
I-Diaphragm (“I-DYE-a-fram”) – a umsipha omise okwedome ehlukanisa isisu sakho (isisu) nesifuba sakho (thoracic). Kukusiza futhi ukuthi uphefumule, ngokusiza amaphaphu akho ukuthi ahambe futhi aphume.
Ukusinda okungenazifo – iphesenti labantu abaphilayo nabangenayo i-lymphoma ngemva kwenani elithile leminyaka.
Ukuqhubeka noma ukuqhubeka kwesifo - lapho i-lymphoma yakho iqhubeka nokukhula. Lokhu kuvame ukuchazwa njengokukhula okungaphezu kwengxenye yesihlanu (ngaphezu kwama-20%) ngenkathi welashwa.
I-DLBCL – uhlobo lwe-non-Hodgkin lymphoma olubizwa ngokuthi Ukusabalalisa i-B-Cell Lymphoma enkulu - Ingabizwa ngokuthi isikhungo se-germinal DLBCL (GCB noma GCB DLBCL) noma i-B-cell DLBCL (ABC noma i-ABC DLBCL ecushiwe).
DNA - i-deoxyribonucleic acid. I-molecule eyinkimbinkimbi ephethe ulwazi lofuzo njengekhodi yamakhemikhali, eyakha ingxenye ye-chromosome kuyi-nucleus yawo wonke amangqamuzana omzimba.
I-lymphoma ephindwe kabili - lapho amaseli e-lymphoma ekhona izinguquko ezimbili ezinkulu ezihlobene lymphoma ezakhini zabo zofuzo. Imvamisa ithathwa njengohlobo lwe-B-cell lymphoma (DLBCL) esakazayo.
DRC – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe, sicela ubheke i- protocol lapha.
E
Isiteji sokuqala - i-lymphoma etholakala endaweni eyodwa noma ezindaweni ezimbalwa ezisondelene, ngokuvamile isigaba 1 noma sesi-2.
I-EATL / EITL – uhlobo lwe-T-cell lymphoma olubizwa ngokuthi I-Enteropathy Ehlobene ne-T-cell Lymphoma.
I-Echocardiography (“ek-oh-CAR-dee-oh-gra-fee”) – ukuskena kwenhliziyo yakho ukuhlola ukwakheka nokunyakaza kwamagumbi enhliziyo yakho namavalvu enhliziyo.
Ukusebenza - ukuthi umuthi usebenza kanjani ngokumelene ne-lymphoma yakho.
I-Electrocardiography (ECG) - indlela yokurekhoda umsebenzi kagesi wemisipha yenhliziyo.
Indlela yokufaneleka - uhlu oluqinile lwemithetho okudingeka uhlangane nayo ukuze ujoyine isilingo somtholampilo. Indlela yokufaka ithi ubani ongajoyina leli cala; indlela yokukhishwa ithi ubani ongakwazi ukujoyina isilingo.
I-Endoscopy - inqubo lapho ikhamera encane kakhulu e-tube eguquguqukayo idluliselwa esithweni sangaphakathi, ukusiza ekuxilongweni nasekwelapheni (isibonelo, ku-gastroscopy i-endoscope idluliselwa emlonyeni ukuya esiswini).
Epidemiology - ucwaningo lokuthi izifo zenzeka kaningi kangakanani emaqenjini ahlukene abantu nokuthi kungani.
I-Epstein-Barr virus (EBV) - igciwane elivamile elibangela i-glaular fever (mono), elingase likhulise ithuba lakho lokuthuthukisa i-lymphoma - ngokuvamile i-Burkitt lymphoma.
Ama-erythrocyte - amangqamuzana abomvu egazi, ezithwala umoya-mpilo emzimbeni wonke.
I-Erythropoietin – ihomoni (i-chemical messenger) eyenziwe yizinso zakho esiza amangqamuzana egazi abomvu ukuthi athuthuke; Kuye kwenziwa futhi umuthi wokwenziwa (njenge-EPO) wokwelapha i-anemia. Abantu abanenkinga yezinso bangadinga i-EPO.
ESHAP – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe bheka i- protocol lapha.
Ukuzijabulisa i-biopsy (“ex-SIH-zhun”) – ukuhlinzwa ukuze kukhishwe isigaxa ngokuphelele; kubantu abane-lymphoma ngokuvamile lokhu kusho ukususwa kwe-lymph node yonke.
Isifo se-Extranodal - i-lymphoma eqala ngaphandle kwesistimu ye-lymphatic.
F
Amanga angalungile - umphumela wokuhlolwa ohlulekayo ukuthola isifo sokutheleleka. Ikhombisa inegethivu, lapho bekufanele ngabe iphozithivu.
Amanga amahle - umphumela wokuhlolwa ophakamisa ukuthi othile unesifo noma ukutheleleka lapho engenaso. Ibonisa ukuthi iphozithivu lapho kufanele ngabe inegethivu.
Ujwayelekile – ugijima emndenini. Izifo zomndeni zithinta amalungu omndeni amaningana, kodwa azihlotshaniswa nofuzo oluthile oluhlonziwe noma ukukhubazeka kofuzo (njengezimo ezizuzwa njengefa).
Ukukhathala - ukukhathala okukhulu kanye nokuntuleka kwamandla, umphumela ovamile ongaseceleni womdlavuza kanye nokwelashwa komdlavuza.
Ukuzala - ikhono lokuba nezingane.
I-Fibrosis (“fye-BROH-sis”) – ukuqina kanye nezibazi zezicubu (njengama-lymph nodes, amaphaphu); kungenzeka ngemva kokutheleleka, ukuhlinzwa noma i-radiotherapy.
I-fine-needle aspiration – ngesinye isikhathi ifushaniswa ibe yi-'FNA'. Kuyinqubo lapho uketshezi oluncane namaseli kususwa esigaxa noma i-lymph node kusetshenziswa inaliti encane. Amaseli abe esehlolwa ngesibonakhulu.
Ukwelashwa komugqa wokuqala – kubhekisela ekwelashweni kokuqala okutholayo ngemva kokutholakala ukuthi une-lymphoma noma i-CLL.
FL – uhlobo lwe-non-Hodgkin lymphoma olubizwa ngokuthi I-Follicular Lymphoma.
I-flow cytometry - indlela yaselabhorethri esetshenziselwa ukubheka amangqamuzana e-lymphoma (noma amanye amangqamuzana) ukusiza ukuxilonga okunembile, nokuhlela ukwelashwa okuphumelelayo kakhulu.
UFollicle – isaka noma indlala encane kakhulu.
Isikhunta – uhlobo lwento ephilayo (into ephilayo) engabangela izifo.
G
I-G-CSF - i-granulocyte colony-stimulating factor. Isici sokukhula esishukumisa umnkantsha ukwenza amangqamuzana egazi amhlophe engeziwe.
I-GDP – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe, bheka i- protocol lapha.
Gene - a ingxenye ye-DNA enolwazi olwanele lwezakhi zofuzo kulo ukuze kwakheke amaprotheni.
I-Genetic – okubangelwa ufuzo.
Nika – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe, sicela ubheke i- protocol lapha.
I-GM-CSF - I-Granulocyte kanye ne-macrophage colony-stimulating factor. Isici sokukhula esishukumisa umnkantsha ukuba wenze amangqamuzana amhlophe egazi namaplatelet engeziwe.
Grade - inombolo enikezwe kusuka ku-1-4 ephakamisa ukuthi i-lymphoma yakho ikhula ngokushesha kangakanani: i-lymphoma yezinga eliphansi ikhula kancane; i-lymphomas yezinga eliphezulu ikhula ngokushesha.
I-Graft-versus-host disease (GvHD) - isimo esingenzeka ngemva kokuba usuthole i-allogeneic stem cell noma ukufakelwa komnkantsha. Ama-T-cell asuka ku-graft (ama-stem cells anikelwe noma umnkantsha) ahlasela amanye amaseli avamile womsingathi (umuntu othole ukufakelwa).
Umphumela we-Graft-versus-lymphoma – umphumela ofana nowe-GvHD kodwa kulokhu umnkantsha wamathambo onikelayo noma ama-stem cells ahlasela futhi abulale amaseli e-lymphoma. Akuqondakali ngokugcwele ukuthi lokhu kwenzeka kanjani, kodwa kunomphumela omuhle.
Gray - isilinganiso sokuthi ingakanani imisebe emuncwa umzimba. I-Radiotherapy 'inqunyelwe' ngezinombolo zeGrey (ifushaniswe ku-'Gy').
Izici zokukhula - amaprotheni enzeke ngokwemvelo alawula ukuthuthukiswa kwamangqamuzana egazi, futhi lapho ekhishwa egazini. Kukhona nemithi enezici zokukhula kuyo. Lezi ngezinye izikhathi zisetshenziswa ngesikhathi sokwelashwa kwe-lymphoma, ukwandisa izinombolo zezinhlobo ezithile zamangqamuzana egazi amhlophe, kanye nezinombolo zamangqamuzana esiqu azungeza egazini (isibonelo, i-G-CSF, GM-CSF).
GZL – uhlobo lwe-non-Hodgkin lymphoma olubizwa ngokuthi Grey Zone Lymphoma. Kodwa inezici zazo zombili i-Hodgkin lymphoma (HL) kanye nohlobo lwe-B-cell lymphoma enkulu esabalele, ebizwa ngokuthi i-primary mediastinal B-cell lymphoma (PMBCL). Kungase kube nzima ukuxilonga ekuqaleni.
H
I-Hematologist (“hee-mah-TOH-lo-jist”) - udokotela onguchwepheshe bezifo zegazi namangqamuzana egazi, okuhlanganisa i-leukemia ne-lymphoma.
I-Hematopoiesis (“HEE-mah-toh-po-esis”) – inqubo yokwenza amangqamuzana egazi amasha, eyenzeka emnkantsheni wakho.
IHemoglobin - iphrotheni ene-iron etholakala kumangqamuzana abomvu egazi athwala umoya-mpilo emzimbeni wakho.
Helicobacter pylori – igciwane elidala ukuvuvukala (ukuvuvukala) kanye nezilonda esiswini sakho futhi lihlotshaniswa ne-subtype ye-lymphoma eqala esiswini sakho (gastric MALT lymphoma).
Umsizi T cell - Ama-T-cell akhuthaza ama-B-cell ukuthi akhe amasosha omzimba amaningi njengengxenye yokusabela komzimba komzimba.
Hickman® umugqa – uhlobo lomugqa ophakathi nendawo (ithubhu elincane eligobekayo). Ukuze ubone imininingwane eyengeziwe mayelana nokwelashwa ngomugqa we-Hickman, sicela ubheke Ulwazi lwesiguli se-eviQ lapha.
Ukwelashwa ngedosi ephezulu – umthetho olandelwayo wokwelapha lapho kunikezwa imithamo emikhulu yokwelashwa okulwa nomdlavuza ngenhloso yokuqeda wonke amaseli esimila. Kodwa, lokhu kuzolimaza namangqamuzana avamile akhiqiza igazi emnkantsheni wakho, ngakho-ke kufanele kulandelwe ukufakelwa kwama-stem cells (ukufakelwa kwe-blood stem cell transplant, i-PBSCT) noma amangqamuzana omnkantsha wethambo (ukufakelwa komnkantsha, BMT).
Umlando – okuphathelene nezicubu noma amaseli.
Histology - ukutadisha ukubukeka kwe-microscopic kanye nesakhiwo sezicubu namaseli.
I-Histopathology - ucwaningo lokubonakala kwe-microscopic yezicubu ezigulayo.
HIV - i-human immunodeficiency virus. Igciwane elihlasela isimiso somzimba sokuzivikela ezifweni futhi lingabangela i-acquired immune deficiency syndrome (AIDS).
HL - I-Hodgkin Lymphoma.
Ihormone – isigijimi sekhemikhali esikhiqizwa indlala bese sithwalwa wuhlelo lwegazi siyiswe kwenye ingxenye yomzimba ukuze sithinte indlela leyo ngxenye esebenza ngayo.
I-HSCT - Ukufakelwa kwe-Hematopoietic Stem Cell.
I-Hyper CVAD – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke amaphrothokholi angezansi:
I-Hyperviscosity – lapho igazi lakho lijiyile kunokujwayelekile. Lokhu kungenzeka uma unamazinga aphezulu amasosha omzimba angavamile egazini lakho. Kuvamile kubantu abane-macroglobulinemia ye-Waldenström.
I-Hypothyroidism - 'i-thyroid engasebenzi kahle'. Kubangelwa ukuntuleka kwehomoni yegilo (i-thyroxine), futhi kungaba umphumela ongasemuva we-radiotherapy entanyeni, noma kusukela ekwelashweni ngama-immune checkpoint inhibitors.
I
ICE – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke amaphrothokholi angezansi:
- Okwe-NHL I-ICE ehlukanisiwe or I-Infusional ICE.
- Okwe-HL I-ICE ehlukanisiwe 0r I-Infusional ICE.
I-ICI - I-immune checkpoint inhibitor - uhlobo lwe-immunotherapy oluqondise amasosha akho omzimba futhi lusize ukuba lubone futhi lulwe nomdlavuza ngempumelelo kakhudlwana (Lezi izigaba ezingaphansi ze-monoclonal antibody).
izivikeli mzimba - uhlelo emzimbeni oluhlanganisa amangqamuzana amhlophe egazi, ubende nama-lymph nodes alwa nezifo. Kungase futhi kubangele ukungezwani komzimba.
Ukugonywa - inqubo yokuvikeleka kokuthile noma ukwakha ukusabela komzimba ukuze ukwazi ukumelana nokutheleleka esikhathini esizayo; enye indlela yokugoma umuntu ukufaka i-antigen (njengegciwane) emzimbeni ngokugoma.
I-Immunocompromised/Immunosuppressed - isimo lapho unamandla amancane okulwa nokutheleleka noma izifo. Kungenzeka ngenxa yesifo noma umphumela ongathandeki wokwelashwa.
Ama-immunoglobulins - ngezinye izikhathi ifushaniswa ibe yi-'Ig', igama lekhemikhali lamasosha omzimba.
I-Immunophenotyping - inqubo ekhethekile esetshenziselwa ukutadisha amaprotheni ebusweni bamaseli e-lymphoma. Isiza udokotela ukuthi abone umehluko phakathi kwama-lymphomas ahlukene futhi enze ukuxilongwa okunembile.
I-Immunosuppression - isimo sokuncipha kwamasosha omzimba okubangwa ukwelashwa. Ingavumela izifo ukuthi zenzeke.
Ukuzivikela komzimba - umuthi owehlisa amandla omzimba okulwa nezifo.
immunotherapy (“eem-you-no-ther-uh-pee”) – ukwelashwa okusiza amasosha omzimba wakho ukuthi alwe nomdlavuza noma i-lymphoma.
Ukuvilapha - i-lymphoma ukuthi ukukhula kancane.
Ukutheleleka - amagciwane, amagciwane, izimuncagazi noma isikhunta esingavamisile ukuhlala emzimbeni (amagciwane) ahlasela umzimba wakho futhi angakugulisa. Uma amasosha akho omzimba engasebenzi kahle, izifo zingavela kumagciwane avame ukuhlala emzimbeni wakho, isibonelo esikhumbeni sakho noma emathunjini akho, kodwa aseqale ukukhula kakhulu.
Ukumnika - ukuba noketshezi (ngaphandle kwegazi) olufakwe emithanjeni.
Isiguli - isiguli esilala esibhedlela ubusuku bonke.
Okokubamba ngaphakathi (IM) - emsipha.
Intrathecal (IT) - oketshezini oluzungeze umgogodla.
I-Intravenous (IV) - emthanjeni.
Igazi elifakwe imisebe - igazi (noma ama-platelet) eliye laphathwa nge-X-ray ngaphambi kokumpontshelwa ukuze libhubhise noma yimaphi amangqamuzana amhlophe; kwenziwa ukuze kuvinjwe isifo esihlobene nokumpontshelwa igazi.
Irradiation - ukwelashwa ngama-X ray noma ezinye izinhlobo zemisebe.
I-IVAC – iphrothokholi yokwelashwa, Ukuze uthole imininingwane eyengeziwe, sicela ubheke protocol lapha.
K
Kinase - iphrotheni enezela ikhemikhali ebizwa ngokuthi i-phosphate kwamanye ama-molecule. Ama-Kinase asiza ukulawula imisebenzi ebalulekile yamaselula, njengokuhlukana kwamaseli, ukukhula nokuphila.
L
I-Laparascope - ikhamera encane kakhulu ekupheleni kweshubhu elide, elincanyana, eliguquguqukayo elingafakwa emzimbeni.
Imiphumela yakamuva - izinkinga zempilo ngenxa yokwelashwa, ezikhula izinyanga noma iminyaka ngemva kokuphela kokwelashwa.
I-leukemia (“loo-KEE-mee-uh”) – umdlavuza wamangqamuzana amhlophe egazi.
Umgomo ophilayo – umgomo oqukethe inguqulo ephilayo, ebuthakathaka yegciwane elidala isifo.
Ukukhishwa kwe-Lumbar - inqubo lapho udokotela efaka khona inaliti endaweni ezungeze umgogodla wakho, futhi asuse isampula encane yoketshezi lwe-cerebrospinal.
I-Lymph – uketshezi olujikeleza emithanjeni ye-lymph. Ngokwengxenye yakhiwe uketshezi oluphuma ezicutshini, futhi ithwala usawoti nama-lymphocyte.
I-Lymphadenopathy (“lim-fa-den-OH-pa-thee”) - ukuvuvukala (ukwandiswa) kwama-lymph nodes.
Uhlelo lwe-Lymphatic - a uhlelo lwamashubhu (imikhumbi ye-lymph), izindlala (lymph nodes), i-thymus kanye ne-spleen esiza ukulwa nezifo futhi, ehlunga uketshezi olumoshayo namaseli avela ezicutshini.
Izindawo ezinama-lymph - indlala encane ye-ovals, ngokuvamile kufika ku-2cm ubude. Ahlanganiswe ndawonye kuwo wonke umzimba wakho ohlelweni lwe-lymphatic - njengentamo, ikhwapha kanye ne-groin. Zisiza umzimba ukulwa nezifo futhi zikhiphe uketshezi olungcolile ezicutshini. Ngezinye izikhathi zaziwa ngokuthi ama-lymph glands.
Imikhumbi ye-lymph - amashubhu athwala uketshezi lwe-lymph futhi axhumene nama-lymph nodes.
Ama-Lymphocyte (“LIM-foh-sites”) – amangqamuzana amhlophe egazi akhethekile ayingxenye yamasosha akho omzimba. Kunezinhlobo ezintathu eziyinhloko - ama-B cell, T cell kanye namaseli abulalayo wemvelo (NK). Lawa maseli akunikeza "inkumbulo ye-immunological". Lokhu kusho ukuthi bagcina irekhodi lakho konke ukutheleleka oke waba nakho ngaphambilini, ngakho uma uthola ukutheleleka okufanayo futhi, bayakubona futhi bakuqede ngokushesha nangempumelelo. Lawa futhi angamaseli athinteka yi-lymphoma ne-CLL.
Izicubu ze-lymphoid (“LIM-FOYD”) - izicubu ezihilelekile ekukhiqizeni i-lymph nama-lymphocyte; iqukethe:
- umkantsha
- i-thymus gland (izitho 'eziyinhloko' ze-lymphoid)
- ama-lymph nodes
- ipeni
- amalaka
- izicubu emathunjini okuthiwa ama-Peyer's patches (izitho 'zesibili' ze-lymphoid).
Lymphoma (“lim-FOH-ma”) – a umdlavuza wama-lymphocyte. Kuthinta kokubili i-lymphatic kanye nesistimu yokuzivikela komzimba.
M
MAB - sicela ubone i-monoclonal antibody.
I-Macrophage - uhlobo lwamangqamuzana amhlophe egazi alwa nezifo namaseli anesifo ngokudla amangqamuzana amabi. Bese bethumela imilayezo yamakhemikhali (abizwa ngokuthi ama-cytokines) ukuze ahehe amanye amangqamuzana omzimba (amangqamuzana alwa nezifo) endaweni, ukuze aqhubeke elwa negciwane noma isifo.
Ukwelashwa kwesondlo – ukwelashwa okuqhubekayo ukugcina i-lymphoma yakho ixolile ngemva kokuba usuqede ukwelashwa kwakho okuyinhloko futhi waba nomphumela omuhle.
Kubi - umdlavuza - into ekhula ngokungalawuleki futhi engahamba iye kwezinye izingxenye zomzimba wakho.
I-MALT – Uhlobo lwe-lymphoma olubizwa ngokuthi I-Mucosa-Associated Lymphoid Tissue. I-MALT ithinta ulwelwesi lwamafinyila (ulwelwesi) lwamathumbu akho, amaphaphu noma izindlala zamathe.
I-MATRix - inqubo yokwelashwa. Ukuze uthole imininingwane eyengeziwe, sicela ubheke i- protocol lapha.
MBL - I-Monoclonal B-cell Lymphocytosis. Lolu akulona uhlobo lomdlavuza noma i-lymphoma, kodwa kwenzeka uma unohlobo olulodwa lweseli oluningi kakhulu egazini lakho. Uma une-MBL ungase ube sengozini enkulu yokuthola i-lymphoma kamuva.
I-MBVP – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe, sicela ubheke i- protocol lapha.
I-MCL - UMantle Cell Lymphoma – uhlobo lwe-non-Hodgkin Lymphoma.
Mediastinum - the ingxenye ephakathi yesifuba sakho okuhlanganisa inhliziyo yakho, uqhoqhoqho (uqhoqhoqho), umgudu womphimbo, imithambo yegazi emikhulu nama-lymph nodes azungeze inhliziyo yakho.
Ikhadi lesexwayiso sezempilo – ikhadi elinolwazi ngesimo sakho kanye nokwelashwa. Uma unikezwa ikhadi lesexwayiso sezempilo, kufanele uhambe nalo ngaso sonke isikhathi.
umzimba – ukuthi amaseli emzimbeni wakho asebenza ngokushesha kangakanani.
I-Metastasis / i-Metastatic - ukusabalala kwamangqamuzana omdlavuza ukusuka lapho aqala khona ukuya kwezinye izindawo zomzimba.
MF - I-Mycosis Fungoides. Uhlobo lwe-T-cell non-Hodgkin Lymphoma ethinta kakhulu isikhumba.
Isifo esincane esisalayo (MRD) - amanani amancane e-lymphoma asele ngemva kokuqeda ukwelashwa kwakho. Uma une-MRD positive, isifo esisele singakhula futhi sibangele ukuphindaphinda (ukubuya komdlavuza). Uma ungenayo i-MRD, unethuba eliphezulu lokuxolelwa okuhlala isikhathi eside.
Igciwane lomzimba elilodwa - uhlobo lomuthi oluqondise ama-receptors athile kumaseli e-lymphoma (noma amanye amangqamuzana anomdlavuza). Bangasebenza ngezindlela eziningi ezihlanganisa:
- Bangakwazi ukumisa izimpawu zesidingo se-lymphoma ukuze umdlavuza ukhule futhi uphile.
- Bangakwazi ukukhumula amangqamuzana e-lymphoma izithiyo zokuzivikela abaye bazisebenzisa ukuze bafihle amasosha omzimba.
- Bangakwazi ukunamathela kumaseli e-lymphoma futhi baxwayise amanye amangqamuzana omzimba omzimba we-lymphoma, okuholela kwamanye amaseli omzimba azolwa.
MRD - Bona isifo esincane esiyinsalela
I-MRI - imaging resonance magnetic. Ukuskena kusetshenziswa inkambu kazibuthe ukunikeza izithombe ezinemininingwane eminingi yengaphakathi lomzimba wakho.
Ulwelwesi lwamafinyila (“myoo-KOH-sah”) – izicubu ezilandelanayo neziningi zezitho zomzimba ezingenalutho, njengamathumbu, imigudu yomoya kanye nemigudu yezindlala evuleka phakathi kwalezi zitho ezingenalutho (njengezindlala zamathe).
I-Mucositis (“myoo-koh-SITE-is”) – ukuvuvukala kwangaphakathi (ulwelwesi) lomlomo wakho.
I-MUGA - ukutholwa okunamasango amaningi. Uhlobo lokuskena oluhlola ukuthi inhliziyo yakho iphampa kangakanani. Abanye abantu bangase babe nalokhu ngaphambi kokuqala ukwelashwa.
Ithimba le-multidisciplinary - iqembu lochwepheshe bezempilo abahlela futhi baphathe ukunakekelwa nokwelashwa kwakho. Kungabandakanya odokotela abavela kochwepheshe abahlukene, abahlengikazi, osonhlalakahle, abelapha emsebenzini, ama-physiotherapist, isazi sokusebenza kwengqondo nokunye - kuye ngezidingo zakho ngabanye.
I-Myelodysplastic syndromes (“MY-loh-dis-PLAS-tik”) – Iqembu lezifo lapho umnkantsha wenza amangqamuzana egazi angasebenzi ngendlela okufanele asebenze ngayo, esikhundleni samangqamuzana egazi anempilo. Ngezinye izikhathi ibizwa ngokuthi 'myelodysplasia'.
UMyeloma – umdlavuza wamaseli e-plasma (uhlobo lwe-B cell) etholakala emnkantsheni. Amaseli e-plasma angamangqamuzana enza amasosha akho omzimba (i-immunoglobulins) kodwa akuyona i-lymphoma.
Izinkinga ze-Myeloproliferative - iqembu lezifo lapho umnkantsha wenza eziningi kakhulu kwelinye, noma izinhlobo eziningi zamangqamuzana egazi.
MZL - I-Marginal Zone Lymphoma. Uhlobo lwe-B-cell non-Hodgkin Lymphoma.
N
I-NED - Bheka "Abukho ubufakazi besifo"
I-needle aspiration biopsy - futhi ngezinye izikhathi eyaziwa ngokuthi 'i-fine-needle aspiration biopsy' noma i-FNAB. Inalithi ezacile ifakwa eqhumeni emzimbeni wakho (njengasentanyeni) ukuze kukhishwe amanye amaseli. Lawa maseli abe esehlolwa ngesibonakhulu.
Neuro - okuphathelene nemizwa yakho noma isimiso sezinzwa.
I-neuropathy - noma yisiphi isifo esithinta izinzwa zakho.
I-Neutropenia ("nyoo-troh-PEE-nee-ya") - amazinga aphansi ama-neutrophils (uhlobo lwengqamuzana elimhlophe legazi) egazini. Ama-neutrophils amangqamuzana okuqala okuthola nokulwa nezifo nezifo. Uma une-neutropenia, maningi amathuba okuthi uthole izifo, ezingaba zimbi ngokushesha.
I-Neutropenic sepsis - ukutheleleka okunzima okungabangela ukuvuvukala kwezitho zakho nemithambo yegazi uma u-neutropenic; ngezinye izikhathi ebizwa 'i-neutropenia ye-febrile' uma izinga lokushisa lingu-38 degrees noma ngaphezulu.
Neutrophils (“nyoo-tro-FILS”) – uhlobo lwamangqamuzana amhlophe egazi alwa nokutheleleka kanye nezifo. Ama-neutrophils angamangqamuzana amasosha omzimba okuqala athola futhi alwe nokutheleleka. Uma lezi ziphansi, maningi amathuba okuthi uthole izifo. Ezinye izifo zingaba zimbi ngokushesha uma une-neutropenia
NHL - I-Non-Hodgkin Lymphoma. Leli yigama elijwayelekile elichaza iqembu lezinhlobo ezingaphansi kwezingama-70 ze-lymphoma. Kungase kuthinte ama-B-cell lymphocyte, ama-T-cell lymphocyte noma amaseli e-Natural Killer.
I-NLPHL - uhlobo lwe-lymphoma olubizwa ngokuthi I-Nodular lymphocyte predominant B-Cell Lymphoma (eyayibizwa ngokuthi i-Nodular Lymphocyte Predominant Hodgkin lymphoma).
Akunabufakazi besifo - igama abanye odokotela, izazi zezifo noma izazi ze-radioologist ezingase zisebenzise ukusho ukuthi izikena zakho nokunye ukuhlola akukhombisi noma iyiphi i-lymphoma emzimbeni wakho. Leli gama ngezinye izikhathi lisetshenziswa esikhundleni sokuxolelwa. Akusho ngempela ukuthi welashiwe, kodwa ukuthi ayikho i-lymphoma ehlonzayo esele ngemva kokwelashwa.
O
O noma Obi – umuthi we-monoclonal antibody obizwa nge-obinutuzumab. Iqondise isamukeli kumaseli e-lymphoma okuthiwa i-CD20. Ingasetshenziswa ne-chemotherapy ukwelapha i-lymphoma (Bheka i-CHOP noma i-CVP), noma njengendlela yokwelapha ngokwakho ukuze inakekele. Ukuze ubone iphrothokholi yokulungiswa kwe-obinutuzumab sicela uchofoze lapha.
Oncologist (“on-COL-oh-jist”) – udokotela ogxile ekuxilongeni nasekulapheni abantu abanomdlavuza; kungase kube udokotela oncologist wezokwelapha onikeza umuthi wokwelapha umdlavuza noma i-radiation oncologist (eyaziwa nangokuthi i-radiotherapist) owelapha umdlavuza nge-radiotherapy.
Oral - ngomlomo, isibonelo, ukwelashwa okuthathwe njengethebhulethi noma i-capsule.
Ukusinda sekukonke – iphesenti labantu abasaphila ngemva kwenani elithile leminyaka, abane-lymphoma noma abangenayo. Ukusinda sekukonke (OS) kuvame ukulinganiswa iminyaka emi-5 neminyaka eyi-10 ngemuva kokuphela kokwelashwa. Izinga lokusinda leminyaka emihlanu noma eyi-10 akusho kusho ukuthi kungenzeka uphile iminyaka emi-5 noma eyi-10 kuphela. Kusho ukuthi izifundo zilandelele abantu ocwaningweni kuphela iminyaka emi-5 noma eyi-10.
P
Odokotela bezingane (“peed-ee-AH-tric”) – okuphathelene nezingane.
I-Palliative - ukwelashwa noma ukunakekelwa okuqeda izimpawu zesimo (njengobuhlungu noma isicanucanu) kunokwelapha isifo.
I-Paraprotein – iphrotheni engenampilo (engajwayelekile) engatholakala egazini noma emchameni.
Okwabazali – imithi noma imisoco enikezwa ngomjovo we-intramuscular noma ngokujova ngomjovo noma ukujova (hhayi ngomlomo).
Impendulo engaphelele - i-lymphoma eyehle okungenani ngesigamu kodwa isekhona i-lymphoma.
Isazi sethambo – udokotela ofunda izicubu namaseli anesifo ngaphansi kwesibonakhulu.
PBS - uhlelo lwezinzuzo zemithi. Imithi esohlwini lwe-PBS ngokwengxenye ixhaswa uhulumeni, okusho ukuthi ungakwazi ukuyithola eshibhile, noma ngaphandle kwezindleko. Ungathola ulwazi olwengeziwe mayelana ne- PBS lapha.
I-PCALCL – uhlobo lwe-T-cell on-Hodgkin lymphoma olubizwa nge-Primary cutaneous i-anaplastic-cell lymphoma enkulu (ikhula esikhumbeni).
I-PCNSL – uhlobo lwe-non-Hodgkin lymphoma olubizwa ngokuthi Uhlelo Lwe-Central Central Lwemizwa Lymphoma (ikhula ebuchosheni nasemgogodleni).
I-Pembro – ukwelashwa kwe-monoclonal antibody okubizwa i-pembrolizumab (Keytruda). Kuyi-immune checkpoint inhibitor, okusho ukuthi ihlubula amangqamuzana e-lymphoma izithiyo zokuzivikela, ukuze amasosha akho omzimba akwazi ukuyibona ngokuphumelelayo futhi alwe nayo. Ukuze uthole imininingwane eyengeziwe nge-pembrolizumab yokwelapha i-Hodgkin Lymphoma, sicela ubheke protocol lapha.
Isimo sokusebenza – indlela yokukala ukuthi ulunge kangakanani futhi ukhuthele.
Ukufakelwa kwe-peripheral stem cell - uhlobo lokwelapha oluqale lusebenzise imithamo ephezulu ye-chemotherapy kanye/noma i-radiotherapy ukuze ibhubhise amangqamuzana omdlavuza, kulandele ukuguqulwa kwama-stem cells ukufaka esikhundleni somnkantsha owonakele (lo monakalo uwumphumela ongaseceleni wemithamo ephezulu yokwelapha ngamakhemikhali).
I-neipathy neuropathy (“per-ih-fural nyoor-O-pah-thee”, O as in “on”) – isimo sesimiso sezinzwa esiseceleni (izinzwa ezingaphandle kobuchopho nomgogodla), ngokuvamile eziqala ezandleni noma ezinyaweni. . Ungase ube nakho ukuba ndikindiki, ukuluma, ukuvutha kanye/noma ubuthakathaka. Kungase futhi kubangelwe amanye ama-lymphomas kanye nemithi ethile elwa nomdlavuza. Kubalulekile ukuthi ubike izimpawu kudokotela noma unesi wakho njengoba bengakwazi ukukusiza.
I-PET - i-positron-emission tomography. Iskena esisebenzisa uhlobo lukashukela olukhipha imisebe ukuze sibheke ukuthi amaseli asebenza kanjani. Kwezinye izinhlobo ze-lymphoma, amaseli asebenza kakhulu ngakho abonakala ngokucacile ku-PET scan.
I-PET/CT scan – iskena lapho kuhlanganiswa khona i-PET ne-CT scan.
Umugqa we-PICC - i-catheter ephakathi efakwe nge-peripheral. Umugqa omaphakathi (ithubhu elithambile eligobekayo) ofakwa endaweni ekude kakhulu nesifuba kuneminye imigqa emaphakathi (njengasengalweni engenhla). Ukuze ufunde kabanzi mayelana nemigqa ye-PICC sicela ubheke Ulwazi lwesiguli se-eviQ lapha.
placebo – ukwelapha okungasebenzi noma 'okwedumi' okuklanyelwe ukubukeka njengomuthi ohlolwayo ovivinyweni lomtholampilo, kodwa okungenanzuzo yokwelapha. Ngokuvamile, iqembu elilodwa labantu ababamba iqhaza ocwaningweni linempatho evamile kanye nomuthi ohlolwayo. Elinye iqembu labantu linokwelashwa okujwayelekile kanye ne-placebo. Ama-placebos asetshenziselwa ukukhipha noma yimiphi imiphumela yengqondo yokuthatha umuthi. Ngeke unikezwe i-placebo ngokwakho uma udinga ukwelashwa okusebenzayo kwe-lymphoma yakho.
I-Plasma - ingxenye yoketshezi yegazi ebamba amangqamuzana egazi; I-plasma iqukethe amaprotheni, usawoti kanye nezinhlanganisela zokuvala igazi.
I-Plasma cell – iseli elakhiwe nge-B lymphocyte ekhiqiza amasosha omzimba.
I-Plasmapheresis (“plas-MAH-fur-ee-sis”) – ngezinye izikhathi okubizwa ngokuthi 'i-plasma exchange'. Inqubo lapho ingxenye yoketshezi yegazi (i-plasma) ihlukaniswa namangqamuzana egazi kusetshenziswa umshini okhethekile futhi amangqamuzana abuyiselwe ekujikelezeni kwegazi; esetshenziswa ukukhipha amaprotheni egazini lomuntu onalawo maprotheni amaningi egazini lakhe.
Amapulatifomu (“PLATE-lets”) – uhlobo lwamangqamuzana egazi olusiza igazi lakho ukuthi lihlule. Ama-platelet abizwa nangokuthi ama-thrombocyte. Ngakho-ke uma utshelwe ukuthi une-thrombocytopenia, kusho ukuthi unamazinga aphansi amaplatelet. Lokhu kusho ukuthi kungenzeka ukuthi wophe futhi ulimele kalula.
I-PMBCL – uhlobo lwe-Non-Hodgkin lymphoma olubizwa ngokuthi I-Primary Mediastinal B-cell Lymphoma (ikhula kuma-lymph nodes endaweni yesifuba sakho.
I-Portaath noma i-Port - uhlobo lomugqa ophakathi nendawo ngezinye izikhathi osetshenziswa ezinganeni ezinechweba noma ikamelo ekugcineni elihlala ngaphansi kwesikhumba; lapho kusetshenziswa umugqa ophakathi, inaliti ifakwa ekamelweni. Ukuze uthole imininingwane eyengeziwe mayelana nokwelashwa nge-portacath, sicela ubheke Ulwazi lwesiguli se-eviQ lapha.
Iseli yomzali – ngesinye isikhathi ibizwa ngokuthi 'iseli elandulela', iseli elingavuthiwe elingakhula libe izinhlobo eziningi zamaseli.
Isibikezelo - ukuthi isifo sakho singathuthuka kanjani nokuthi kungenzeka usabele kahle kangakanani ekwelashweni. Ziningi izinto ezithinta ukuqagula okuhlanganisa uhlobo lwakho lwesimila kanye neminyaka yakho nempilo jikelele.
Isikhawu esingaqhubeki - isikhathi phakathi kokwelashwa kanye ne-lymphoma iqala ukwanda futhi. Ngezinye izikhathi kuthiwa 'isikhathi samahhala somcimbi'.
Ukusinda okungenanqubekela phambili - isikhathi lapho umuntu ephila ngaphandle kwe-lymphoma yakhe eqala ukwanda futhi.
I-Prophylactic noma i-Prophylaxis - ukwelashwa okunikezwa ukuvimbela ukugula noma ukusabela.
amaprotheni - atholakala kuzo zonke izinto eziphilayo, amaprotheni anemisebenzi eminingi, kuhlanganise nokusiza ukulawula indlela amangqamuzana ethu asebenza ngayo kanye nokulwa nezifo.
I-PTCL – uhlobo lwe-T-cell non-Hodgkin lymphoma olubizwa ngokuthi I-Peripheral T-cell lymphoma. I-PTCL ihlanganisa izinhlobo ezincane:
- I-Peripheral T-cell lympham ayikho ngenye indlela eshiwo (PTCL-NOS)
- I-Angioimmunoblastic T-cell lymphoma (AITL)
- I-Anaplastic big cell lymphoma (ALCL)
- I-Cutaneous T-cell lymphoma (CTCL)
- I-Sezary Syndrome (SS)
- I-T-cell leukemia/lymphoma yabadala (ATLL)
- I-Enteropathy-Type T-cell lymphoma (EATL)
- I-Nasal Natural killer T-cell lymphoma (NKTCL)
- I-Hepatosplenic Gamma delta T-cell lymphoma.
I-PVAG – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe, sicela ubheke i- protocol lapha.
R
R noma i-Ritux – i-monoclonal antbody treatment ebizwa nge-rituximab (futhi i-Mabthera noma i-Rituxan). Iqondise isamukeli kumaseli e-lymphoma okuthiwa i-CD20. Ingasetshenziswa nezinye izindlela zokwelapha (bona i-CHOP, i-CHEOP, i-DA-R-EPOCH, i-CVP), noma isetshenziswe yodwa ekwelashweni kwesondlo. Inganikezwa njengokujova emthanjeni wakho (IV), noma njengomjovo ongaphansi kwesikhumba esicutshini esinamafutha esisu sakho, engalweni noma emlenzeni. Ukuze uthole imininingwane eyengeziwe ngokulungiswa kwe-rituximab sicela ubheke imigomo engezansi:
I-Radiographer - umuntu othatha ama-radiographs (ama-X-ray) futhi enze ezinye izikena (i-radiographer yokuxilonga) noma onikeza i-radiotherapy (i-radiographer yokwelapha).
I-Radioimmunotherapy - ukwelashwa kusetshenziswa i-monoclonal antibody enezinhlayiyana zemisebe enamathiselwe kuyo, ngakho ingaqondisa ngqo iseli le-lymphoma. Lokhu kuqinisekisa ukuthi i-radiotherapy ifika kumaseli e-lymphoma ngaphandle kokuthinta amaseli anempilo aseduze.
Isazi semisakazo - udokotela ohumusha ama-radiographs (ama-X-ray) kanye nezikena; ingase futhi yenze ama-biopsies isebenzisa izikena ukuze kuqinisekiswe ukuthi izicubu ezilungile ziyathathwa ukuze zihlolwe.
I-Radiotherapist - udokotela ogxile ekwelapheni abantu esebenzisa i-radiationtherapy, eyaziwa nangokuthi 'i-clinical oncologist' noma “i-radiation oncologist”.
Radiotherapy (“ray-dee-oh-ther-ap-ee”) – ukwelashwa lapho imishayo enamandla, egxiliswe ngokucophelela yemisebe (njenge-X-ray) isetshenziselwa ukulimaza nokubulala i-lymphoma namanye amangqamuzana omdlavuza. Ngezinye izikhathi ibizwa ngokuthi 'i-external beam radiotherapy'.
I-Randomisation - indlela esetshenziswa ezinhlolweni zokwelashwa, ukuqinisekisa ukuthi umhlanganyeli ngamunye unethuba elifanayo lokufakwa emaqenjini okwelapha ahlukene.
I-R-CHEOP14 – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
I-R-CHOP – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke imigomo lapha - I-R-CHOP14 or I-R-CHOP21.
I-R-DHAOx – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha
I-R-DHAP – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
I-R-GDP – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
I-R-GemOx – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
I-R-HIDAC – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
I-R-Maxi-CHOP -iphrothokholi yokwelashwa. Ukuze uthole imininingwane eyengeziwe sicela ubheke protocol lapha.
I-R-Mini-CHOP – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
Amaseli abomvu egazi - amangqamuzana egazi athwala umoya-mpilo emzimbeni wonke; eyaziwa nangokuthi 'i-erythrocytes'.
Reed-Sternberg cell - iseli elingavamile lokho kubukeka 'njengamehlo esikhova' ngaphansi kwesibonakhulu. Lawa maseli ngokuvamile akhona kubantu abane-Hodgkin Lymphoma.
I-Refractory - igama elisetshenziselwa ukuchaza lapho isifo singaphenduli ekwelashweni, okusho ukuthi ukwelashwa akusenawo umthelela kumangqamuzana omdlavuza. Uma unesifo se-refractory, udokotela wakho angase akunikeze uhlobo oluhlukile lokwelapha.
Ukushiyeka - igama elisetshenziswa uma i-lymphoma yakho ibuya ngemva kokwelashwa, bese kuba yisikhathi ngaphandle kwesifo esisebenzayo.
Ukuthethelelwa (“ree-MI-shon”) – isikhathi esingemva kokwelashwa kwakho lapho bungekho ubufakazi besifo obubonakala emiphumeleni yakho yokuhlolwa (ukukhululwa okuphelele). Ukukhululwa okuyingxenye yilapho inani le-lymphoma emzimbeni wakho lehle okungenani ngesigamu, kodwa alikapheli ngokuphelele; futhi 'ukukhululwa okuhle kwengxenye' yilapho izingxenye ezintathu kwezine zesimila sezihambile.
Ukuphefumula - okuhlobene nokuphefumula noma nezitho zokuphefumula (amaphaphu nemigudu yomoya).
Imphendvulo - lapho i-lymphoma incipha noma inyamalala ngemva kokwelashwa. Bheka futhi 'impendulo ephelele' kanye 'nempendulo engaphelele'.
RICE – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke iphrothokholi lapha I-RICE yokufakelwa or I-RICE ehlukanisiwe.
S
Skena - – isivivinyo esibheka ngaphakathi emzimbeni, kodwa ithathwa ngaphandle komzimba, njenge-CT scan noma i-ultrasound scan.
Ukwelashwa kolayini wesibili – Ukwelashwa komugqa wesibili kwenzeka lapho, ngemva kokwelashwa kwakho kwasekuqaleni (ukwelashwa komugqa wokuqala) isifo sakho sibuya, noma uma ukwelashwa kungasebenzi. Kuya ngokuthi kwakukudala kangakanani ukwelashwa kwakho komugqa wokuqala, ungase uthole ukwelashwa okufanayo, noma ube nohlobo oluhlukile lokwelashwa. Ngemuva kokwelashwa komugqa wesibili ongase ube nakho Ukwelashwa komugqa wesithathu noma wesine uma i-lymphoma yakho ibuya noma ingaphenduli ekwelashweni komugqa wesibili.
Ukuzijabulisa - lapho unikezwa umuthi wokukusiza uphumule ngaphambi kwenqubo. Kungakwenza ulale, futhi ungase ungayikhumbuli inqubo, kodwa ngeke uquleke.
Ukuthula - umuthi onikezwe wona ukukusiza uphumule.
Sepsis - ukusabela okungathí sina komzimba ekuthelelekeni okungabangela ukulimala kwezicubu kanye nokwehluleka kwezitho; i-sepsis ingaba yingozi.
Umphumela oseceleni - an umphumela ongafunwa yokwelashwa.
SLL – uhlobo lwe-B-Cell, i-non-Hodgkin lymphoma ebizwa I-lymphocytic lymphoma encane. Ifana kakhulu neChronic lymphocytic leukemia (CLL), kodwa amangqamuzana e-lymphoma atholakala kakhulu kuma-lymph nodes akho nakwezinye izicubu ze-lymphatic.
I-SMARTE-R-CHOP – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
SMILE – inqubo yokwelapha. Ukuze uthole imininingwane eyengeziwe sicela ubheke i- protocol lapha.
I-SMZL - I-Splenic Marginal Zone Lymphoma, uhlobo oluncane lwe-Non-Hodgkin Lymphoma oluqala kuma-B-cell lymphocyte kubende lwakho.
Umhlengikazi onguchwepheshe – umhlengikazi wakho onguchwepheshe (ngezinye izikhathi obizwa ngokuthi uchwepheshe wabahlengikazi basemtholampilo noma i-CNS) ngokuvamile uzoba umuntu wokuqala okufanele umthinte nganoma yiziphi izinkathazo noma izinto ezikukhathazayo. Uchwepheshe we-lymphoma uqeqeshelwe ukunakekela abantu abane-lymphoma futhi angakusiza uqonde kabanzi ngesifo sakho, ukwelashwa kwaso kanye nendlela yokuzinakekela ngesikhathi sokwelashwa.
ubende - isitho esiyingxenye yamasosha akho omzimba. Ilingana nesibhakela esigoqiwe, futhi ilala ngaphansi nje kwezimbambo zakho ohlangothini olungakwesokunxele lomzimba wakho, ngemuva kwesisu sakho. Ibandakanyeka ekulweni nezifo, futhi ikuhlunga igazi, ikhiphe izinhlayiya zangaphandle futhi ibhubhise amangqamuzana egazi amadala.
Splenectomy - ekhipha ubende ngokuhlinzwa.
I-Splenomegaly (“slen-oh-meg-alee”) – ukuvuvukala (ukwandiswa) kobende.
I-SPTCL – uhlobo lwe-T-cell non-Hodgkin lymphoma olubizwa nge-Subcutaneous panniculitis-like T-cell lymphoma oluvame ukuvela esikhumbeni.
SS – uhlobo lwe-T-cell lymphoma olukhula esikhumbeni, olubizwa I-Sezary Syndrome.
Isifo esizinzile - i-lymphoma ehlala ifana (ayihambanga noma iqhubekele phambili).
Stage - umhlahlandlela woku zingaki, futhi yiziphi izindawo umzimba wakho uthintwa lymphoma. Kunezigaba ezine ezisetshenziselwa ukuchaza izinhlobo eziningi ze-lymphoma, ezivame ukubhalwa ngezinombolo zamaRoma njengesigaba I kuya esigabeni IV.
Isiteji - inqubo yokuthola ukuthi yini isigaba lymphoma yakho kuyinto. Uzoba namaskena kanye nokuhlolwa ukuze uthole ukuthi uphetheni esiteji.
Ukuvunwa kwe-stem cell -ebizwa futhi iqoqo le-stem cell, inqubo yokuqoqa ama-stem cells egazini (okuzosetshenziswa ekufakelweni kwe-stem cell). Amaseli e-stem aqoqwa futhi acutshungulwe ngomshini we-apheresis.
Ukufakelwa kwe-stem cell – inqubo yokunikeza ama-stem cells avunwe ngaphambilini kumuntu. Ukufakelwa kwe-stem cell kungenzeka:
- Ukufakelwa kwe-stem cell kwe-Autologous - lapho uvuna amaseli akho bese uwathola futhi ngokuhamba kwesikhathi.
- Ukufakelwa kwe-Allogeneic stem cell - lapho omunye umuntu enikela ngama-stem cells kuwe.
Amaseli we-stem - amaseli angavuthiwe angakhula abe izinhlobo ezahlukene zamaseli avuthiwe ngokuvamile atholakala egazini elinempilo.
I-Steroids - amahomoni avela ngokwemvelo ahilelekile emisebenzini eminingi yemvelo yomzimba; ingabuye yenziwe futhi inikezwe njengokwelashwa.
I-subcutaneous (“sub-queue-TAY-nee-us”) – izicubu ezinamafutha ngaphansi kwesikhumba sakho.
Ukuhlinzwa - Ukwelashwa okubandakanya ukusikwa emzimbeni ukuze ushintshe noma ukhiphe okuthile.
Isibonakaliso - noma yiluphi ushintsho emzimbeni wakho noma endleleni osebenza ngayo; ukwazi kwakho izimpawu ingasiza odokotela ukuthi bahlole izifo.
Okuhlelekile - okuthinta umzimba wakho wonke (hhayi nje izitho zasendaweni noma zasendaweni).
T
I-TBI - bona i-radiation yomzimba wonke.
T-cells / T-cell lymphocyte - amaseli amasosha omzimba asiza ukuvikela kumagciwane kanye nomdlavuza. Ama-T-cell akhula emnkantsheni wakho, bese ehambela futhi avuthwe ku-thymus gland yakho. Ziwuhlobo lwengqamuzana elimhlophe legazi futhi zingaba nomdlavuza obangela i-T-cell lymphoma.
TGA - Ukuphathwa Kwempahla Yokwelapha. Le nhlangano iyingxenye yoMnyango Wezempilo Kahulumeni Wase-Australia futhi ilawula ukugunyazwa kwemithi nokunye ukwelashwa okuhlobene nempilo. Ungathola imininingwane eyengeziwe mayelana ne- TGA lapha.
Thrombocytopenia (“throm-boh-SITE-oh-pee-nee-yah”) – uma wena abanawo ama-platelet anele egazini lakho; Ama-platelet asiza igazi lakho ukuthi lihlule, ngakho-ke uma une-thrombocytopenia, maningi amathuba okuthi wophe futhi ugwaze kalula.
thymus - idlala elincane eliyisicaba phezulu kwesifuba sakho, nangemuva kwethambo lakho lesifuba. Kulapho ama-T cell akho akhula khona.
Izicubu – iqoqo lamaseli afanayo, abukeka ngokufanayo futhi anomsebenzi ofanayo, ahlanganiswe ndawonye ukuze akhe izingxenye zomzimba wakho. Isibonelo - iqoqo lamaseli alukwe ndawonye ukuze enze imisipha yakho abizwa ngokuthi izicubu zemisipha.
TLS - bheka i-tumor lysis syndrome.
Isihloko - ukubeka umuthi ngqo phezu kwesikhumba, njengokhilimu noma lotion.
Ingqikithi yemisebe yomzimba - i-radiotherapy enikezwa umzimba wakho wonke, hhayi nje ingxenye yawo; ngokuvamile inikezwa ukubulala noma yimaphi amaseli e-lymphoma asele emzimbeni ngaphambi kokufakelwa kwe-stem cell.
Uguquko - the inqubo ye-lymphoma ekhula kancane, ephenduka i-lymphoma ekhula ngokushesha.
Ukudluliselwa - ukunikezwa kwegazi noma imikhiqizo yegazi (njengamaseli abomvu, ama-platelet noma ama-stem cells) emthanjeni.
Isifo esihlobene ne-Transfusion-associated graft-versus-host (TA-GvHD) - inkinga engavamile kodwa engathi sína yokumpontshelwa igazi noma i-platelet lapho amangqamuzana amhlophe egazini elimpontshelwe, ehlasela amangqamuzana akho phakathi noma ngemva kokumpontshelwa. Lokhu kungavinjelwa ngokufaka imisebe yegazi namaplatelet (lokhu kwenzeka ebhange legazi, ngaphambi kokuba kufike kuwe).
I-Tumor - ukuvuvukala noma isigaxa esivela eqoqweni lamaseli; ingaba yingozi (hhayi umdlavuza) noma ibe yingozi (umdlavuza).
I-Tumor flare - ngezinye izikhathi okubizwa ngokuthi 'i-flare reaction', lokhu ukwanda kwesikhashana kwezimpawu ze-lymphoma ngemva kokuqala ukwelashwa. Kuvame kakhulu emithini ethile, njenge-lenalidomide, i-rituximab (i-rituximab flare) ne-pembrolizumab.
I-Tumor lysis syndrome - ukugula okungajwayelekile kodwa okubi kakhulu okungenzeka lapho amangqamuzana e-tumor efa ekhulula amakhemikhali emikhiqizo ekujikelezeni kwegazi okuphazamisa i-metabolism; ngokuvamile kwenzeka ngemva kwenhlanganisela yokwelapha ngamakhemikhali noma ngezinye izikhathi ngemva kokwelashwa ngezidakamizwa ezingama-steroid.
Izimpawu zesimila – iphrotheni noma olunye uphawu egazini noma emchameni wakho oluvame ukuba khona kuphela uma kuvela umdlavuza noma esinye isifo.
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Umgomo/umgomo - umuthi onikezwe ukusiza amasosha omzimba wakho ukuthi amelane nezifo. Lo muthi ungase usebenze ngokukunikeza umthamo omncane wegciwane noma wesilwane esidala lokho kutheleleka (isilwane ngokuvamile sibulawa kuqala noma silungiswe ukuze kuphephe); ngakho amasosha akho omzimba akwazi ukwakha ukumelana nawo. Eminye imithi yokugoma isebenza ngezindlela ezahlukene. Kubalulekile ukukhuluma nodokotela wakho nganoma yimiphi imigomo njengoba ukugoma okuthile akuphephile kubantu abane-lymphoma ngenkathi belashwa.
I-Varicella zoster - igciwane elibanga inkukhu kanye nama-shingles.
I-alkaloid ye-Vinca - uhlobo lomuthi we-chemotherapy owenziwe emndenini wesitshalo se-periwinkle (Vinca); izibonelo yi-vincristine ne-vinblastine.
igciwane – isidalwa esincane esibanga izifo. Ngokungafani nama-bacterium, amagciwane awakhiwe amangqamuzana.
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Buka futhi Ulinde – okubizwa nangokuthi ukuqapha okusebenzayo. Isikhathi lapho une-lymphoma ekhula kancane (i-indolent) futhi ayidingi ukwelashwa, kodwa udokotela wakho uzoqapha ngentshiseko ngalesi sikhathi. Ukuze uthole imininingwane eyengeziwe ekubukeni nasekulindeni sicela ubheke yethu ikhasi lapha.
Iseli legazi elimhlophe – iseli elitholakala egazini nakwezinye izicubu eziningi esiza imizimba yethu ukuthi ilwe nezifo. Amaseli ethu amhlophe afaka:
- Ama-lymphocyte (ama-T-cell, ama-B-cell kanye namaseli e-NK) - Lawa angaba nomdlavuza ku-lymphoma
- Ama-granulocyte (ama-neutrophils, ama-eosinophils, ama-basophils nama-mast cell). Lezi zilwa nezifo kanye nokutheleleka ngokukhipha amakhemikhali anobuthi emangqamuzaneni ukuze abulale amangqamuzana anesifo namagciwane. Kodwa amakhemikhali abawakhiphayo angabangela nokuvuvukala
- Ama-monocyte (ama-macrophages namaseli e-dendritic) - Lawa maseli alwa nokutheleleka noma amangqamuzana anesifo ngokuwagwinya bese evumela ukuthi ama-lymphocyte akho azi ukuthi kukhona ukutheleleka. Ngale ndlela “basebenza” ama-lymphocyte akho ukuze alwe nokutheleleka nezifo kangcono.
WM - I-Macroglobulinemia kaWaldenstrom – uhlobo lwe-B-cell non-Hodgkin lymphoma.
