Ka hoʻomaopopo ʻana i nā Lymphocytes T-cell
No ka hoʻomaopopo ʻana iā AITL, pono ʻoe e ʻike e pili ana i kāu lymphocytes T-cell.
He ʻāpana koʻikoʻi nā lymphocytes T-cell o kā mākou ʻōnaehana pale e pale iā mākou mai ka maʻi a me ka maʻi, a hoʻoponopono i kā mākou ʻōnaehana pale e pale aku i nā hōʻeha autoimmune. Hana ʻia ka hoʻouka kaua ʻana i ka wā ʻoi aku ka hana o kā mākou ʻōnaehana pale ʻole a hoʻomaka e hakakā i ko mākou kino ponoʻī ma mua o ka maʻi a me ka maʻi.
Hana ʻia nā pūnae T i loko o ko mākou iwi iwi, akā ma mua o ko lākou oʻo ʻana, hele lākou ma o kā mākou lymphatic system a hiki i ko mākou thymus kahi e hoʻomau ai lākou e ulu a oʻo.
E pili ana i nā Lymphocytes T-cell
- Hana ʻia nā pūnae T i loko o ko mākou iwi iwi, ʻoʻo i loko o ko mākou thymus, akā hiki ke noho ma kekahi ʻāpana o kā mākou lymphatic system - me kā mākou lymph nodes.
- Pono e ho'ā 'ia nā pūnaewele T e hana pono. Hoʻomaha maʻamau lākou i loko o kā mākou thymus, nā lymph nodes a i ʻole nā wahi ʻē aʻe o kāu ʻōnaehana lymphatic, a ala wale lākou a hakakā i ka maʻi i ka wā e hōʻike aku ai nā cell immune ʻē aʻe iā lākou he maʻi a maʻi paha e hakakā. I ko lākou ala ʻana, hiki i nā pūnae T ke hele i kekahi ʻāpana o ko mākou kino e hakakā i ka maʻi a i ʻole ka maʻi.
- ʻO kekahi mau T-cell ke kuleana no ka "hoʻoponopono" i ka pane immune. ʻO ia hoʻi, i ka wā i luku ʻia ai ka maʻi, ka “Nā pūnaewele T hoʻoponopono” e haʻi aku i nā pūnaewele ʻē aʻe e "kū i lalo" i ʻole lākou e hoʻomau i ka hakakā ʻana a hoʻopilikia i kā mākou mau sela maikaʻi ke pau ka maʻi.
- Ma hope o ka hakakā ʻana i kahi maʻi a i ʻole maʻi, lilo kekahi mau T-cell “Nā pūnāwai T hoʻomanaʻo” a hoʻomanaʻo lākou i nā mea a pau e ʻike ai e pili ana i ka maʻi a pehea e hakakā ai. ʻO ia ala, inā loaʻa hou iā mākou ka maʻi like a i ʻole ka maʻi, hiki i kā mākou ʻōnaehana pale ʻana ke hakakā me ka wikiwiki a me ka maikaʻi.
- Hiki i kekahi mau T-cell ke kōkua i nā mea ʻē aʻe, e like me nā lymphocytes B-cell e hana pono. Ua kapa ʻia kēia mau T-cell "Kōkua T-cell”.
He aha ka manaʻo o ka angioimmunoblastic?
angio - he inoa lapaʻau i hoʻohana ʻia no nā kīʻaha koko. I loko o ka Angioimmunoblastic T-cell Lymphoma, ulu nā wahi o kou kino e ka lymphoma i nā kīʻaha koko liʻiliʻi a ʻano like ʻole. He mea kū hoʻokahi kēia i kēia subtype o lymphoma.
Immuno – ʻo ia ka inoa no ka cell immune (nā pūnana e hakakā ana i ka maʻi a me ka maʻi) – e like me ka lymphocyte – i kēia hihia, he T-cell lymphocyte.
Blastic - e pili ana i ka oʻo o ke kelepona. ʻO ka pahū he mea ʻōʻō ʻole - ʻaʻole i hoʻokumu piha ʻia.
No laila, ua wehewehe ʻo Angioimmunoblastic T-cell Lymphoma i ka lymphoma mai ka maʻi maʻi ʻaʻai ʻole, nā pūnaewele kino ʻole (T-cell) me nā kīʻaha koko ʻino ma ke kahua o ka lymphoma.
Ka nānā 'ana o ka Angioimmunoblastic T-cell Lymphoma (AITL)
Hoʻokumu ʻo AITL i ka wā e lilo ai nā pūnaʻi T oʻo ʻole i loko o kāu mau lymph nodes a i ʻole nā ʻāpana ʻē aʻe o kāu ʻōnaehana lymphatic i ka maʻi kanesa. ʻAʻole maopopo iā mākou ke kumu o kēia i kekahi poʻe, akā ʻike mākou e hiki mai ana kahi loli i kāu mau genes e hāʻawi i nā ʻōlelo aʻoaʻo e pili ana i ka ulu ʻana a me ka hana ʻana o nā cell. Manaʻo ʻia inā ua loaʻa iā ʻoe kekahi maʻi maʻi i ka wā ma mua, hiki paha iā ʻoe ke hoʻonui i ka pilikia o ka hoʻomohala ʻana i kēia mau hoʻololi genetic, akā naʻe, pono ka noiʻi hou e hōʻoia i kēia.
Ke hiki mai nā hoʻololi genetic, ʻaʻole loaʻa hou nā ʻōkuhi i nā ʻōlelo kūpono a hoʻomaka e hoʻomohala me nā hoʻololi i loko o ia mau mea e ulu ai lākou i kahi ala ʻole. Hoʻololi lākou i hiki ʻole iā lākou ke oʻo a hana i kā lākou hana o ke kaua ʻana i ka maʻi a me ka maʻi kūpono.
Hiki i ka AITL ke hoʻopilikia i ka poʻe o kēlā me kēia makahiki me nā keiki, akā maʻamau ka mea maʻamau i nā poʻe ʻelemakule ma mua o 60 mau makahiki.
No ka ʻike hou aku e pili ana i ke kumu a me ke kumu e ulu ai ka lymphoma e kaomi i ka loulou ma lalo nei.
ʻO kahi hōʻailona maʻamau o AITL he puʻupuʻu e piʻi mai ana ma lalo o kou ʻili ma kou ʻāʻī, ka ʻāʻī a i ʻole ka ʻāʻī āu e ʻike ai a manaʻo paha. Hoʻokumu ʻia kēia ma muli o ka pehu ʻana o ka lymph node i ka piha ʻana i nā pūnaewele lymphoma cancerous. Hiki ke komo i nā hōʻailona ʻē aʻe:
- Pau ka maʻi
- ʻO ka manawa pōkole
- ʻO ka ʻōpū a i ʻole ka ʻeha ʻeha
- ami eha
- 'Oloke
- ʻO ka ʻili ʻili a/a i ʻole ka ʻūhā
- B-hōʻailona
Hiki ke loaʻa nā hōʻailona ʻē aʻe i ka poʻe me ka lymphoma
ʻO ka hōʻoia, ka hoʻonohonoho ʻana a me ka helu ʻana o AITL
Hiki ke paʻakikī ka ʻike ʻana iā AITL i kekahi manawa a hiki ke lawe i kekahi mau pule.
Inā manaʻo kāu kauka e loaʻa iā ʻoe ka lymphoma, pono lākou e hoʻonohonoho i nā hoʻokolohua koʻikoʻi. Pono kēia mau ho'āʻo e hōʻoia a hoʻopau paha i ka lymphoma ke kumu o kāu mau hōʻailona. No ka mea he nui nā ʻano subtypes o AITL, loaʻa paha iā ʻoe nā hoʻokolohua hou e ʻike ai i kāu mea. He mea koʻikoʻi kēia no ka mea ʻokoʻa ka hoʻokele a me ka mālama ʻana i kāu subtype me nā ʻano subtype ʻē aʻe o AITL.
No ka ʻike ʻana iā AITL pono ʻoe i kahi biopsy. ʻO ka biopsy kahi hana e wehe ai i kahi ʻāpana, a i ʻole nā poʻo lymph i hoʻopilikia ʻia a/ a i ʻole kahi laʻana o ka iwi iwi. A laila nānā ʻia ka biopsy e kahi ʻepekema i ka pathology e ʻike inā he mau loli e kōkua i ke kauka e hōʻoia i ka AITL.
Ke loaʻa iā ʻoe kahi biopsy, loaʻa paha iā ʻoe kahi maʻi anesthetic kūloko a i ʻole maʻamau. E pili ana kēia i ke ʻano o ka biopsy a me kahi ʻāpana o kou kino i lawe ʻia mai. Aia nā ʻano biopsies like ʻole, a pono paha ʻoe ma mua o hoʻokahi no ka loaʻa ʻana o ka laʻana maikaʻi loa.
Nā ho'āʻo koko
Lawe ʻia nā hoʻāʻo koko i ka wā e hoʻāʻo ai e hōʻoia i kāu lymphoma, akā i loko o kāu mālama ʻana e hōʻoia i ka hana pono ʻana o kāu mau kino a hiki ke hoʻokō i kāu lapaʻau.
Biopsy kumu a i ʻole ka nila maikaʻi
Lawe ʻia nā biopsies koʻikoʻi a i ʻole ka nila maikaʻi no ka wehe ʻana i kahi laʻana o ka pehu lymph node, ka ʻōpū a i ʻole ka ʻili i hoʻopilikia ʻia e nānā i nā hōʻailona o AITL.
Hoʻohana maʻamau kāu kauka i kahi anesthetic kūloko e hoʻopau i ka wahi i ʻole ʻoe e ʻeha i ka wā o ke kaʻina hana, akā e ala ʻoe i kēia biopsy. A laila e hoʻokomo lākou i kahi nila i loko o ka ʻōpū lymph pehu a i ʻole ka puʻupuʻu a wehe i kahi laʻana o ka ʻiʻo.
Inā hohonu i loko o kou kino ka pehu lymph node a puʻupuʻu paha, hiki ke hana ʻia ka biopsy me ke kōkua o ke ultrasound a i ʻole ke alakaʻi x-ray (kiʻi).
Loaʻa paha iā ʻoe kahi maʻi anesthetic maʻamau no kēia (kahi e hiamoe ai ʻoe no kahi manawa liʻiliʻi). Loaʻa paha iā ʻoe kekahi mau humuhumu ma hope.
ʻOi aku ka nui o nā biopsies o ka nila ma mua o ka biopsy nila.
ʻO ka biopsy node excision
Hana ʻia nā biopsies node excisional inā hohonu loa kou ʻōpū lymph a i ʻole ka ʻōpū i loko o kou kino a hiki ʻole ke loaʻa ʻia e kahi biopsy kumu a i ʻole ka nila. Loaʻa iā ʻoe kahi maʻi maʻi maʻi maʻi e hoʻomoe iā ʻoe no kahi manawa liʻiliʻi i noho mālie ʻoe, ʻaʻohe ʻeha.
I loko o kēia kaʻina hana, e hoʻoneʻe ke kauka lapaʻau i ka puʻupuʻu lymph holoʻokoʻa a hoʻouna ʻia i ka pathology no ka hoʻāʻo.
E loaʻa iā ʻoe kahi ʻeha liʻiliʻi me nā humuhumu liʻiliʻi, a me kahi ʻaʻahu ma luna.
Noho mau nā humuhumu no 7-10 mau lā, akā na kāu kauka a kahu hānai paha e aʻo iā ʻoe i ke ʻano o ka mālama ʻana i ka lole, a me ka manawa e hoʻi ai e wehe i nā humuhumu.
ʻike,
Ke hoʻonohonoho
Kāleka
ʻO ke kau ʻana o ka Angioimmunoblastic T-cell lymphoma (AITL)
Ke hōʻoia ʻia kāu hōʻoia ʻana o AITL he mau hoʻāʻo hou aʻe kāu e ʻike ai i ka nui o nā wahi o kou kino i hoʻopilikia ʻia e ka lymphoma. Kapa ʻia kēia ʻano hoʻokūkū.
Hōʻike ka staging i ka nui o kou kino i hoʻopilikia ʻia e kāu lymphoma - a i ʻole, pehea ka lōʻihi o ka laha ʻana mai kahi i hoʻomaka mua ai.
Hiki i nā pūnae T ke hele i kekahi wahi o kou kino. 'O ia ho'i, hiki i nā pūnaewele lymphoma (nā T-cell ma'i 'a'ai), hiki ke hele i kekahi wahi o kou kino. Pono ʻoe e hoʻāʻo hou aʻe e ʻike i kēia ʻike. Kapa ʻia kēia mau hoʻokolohua he staging tests a ke loaʻa iā ʻoe nā hopena, e ʻike ʻoe inā loaʻa iā ʻoe ka pae mua (I), pae ʻelua (II), pae ʻekolu (III) a i ʻole lymphoma pae ʻehā (IV).
E hilinaʻi kāu pae o AITL ma:
- ʻEhia mau wahi o kou kino i loaʻa i ka lymphoma.
- Ma kahi e komo ai ka lymphoma inā aia ma luna, ma lalo a ma nā ʻaoʻao ʻelua o kāu diaphragm (he ʻiʻo nui, ʻano dome ma lalo o ka iwi ʻaoʻao e hoʻokaʻawale i ka umauma mai kou ʻōpū).
- Inā ua laha ka lymphoma i kou iwi iwi a i ʻole nā ʻano ʻē aʻe e like me ke ake, ka māmā, ka ʻili a i ʻole ka iwi.
Kapa ʻia nā pae I a me II 'o ka pae mua a i ʻole ka palena palena' (e pili ana i kahi ʻāpana o kou kino).
Ua kapa ʻia nā pae III a me IV he 'pae holomua' (ʻoi aku ka laulā).
Hana 1 | Hoʻokahi wahi puʻupuʻu lymph i hoʻopilikia ʻia, ma luna a ma lalo paha o ka diaphragm* |
Hana 2 | ʻelua a ʻoi aʻe paha nā ʻāpana lymph node ma ka ʻaoʻao hoʻokahi o ka diaphragm* |
Hana 3 | ma ka liʻiliʻi hoʻokahi wahi lymph node ma luna a ma ka liʻiliʻi loa hoʻokahi wahi lymph node ma lalo o ka diaphragm* e pili ana |
Hana 4 | Aia ka lymphoma i loko o nā pūnana lymph he nui a ua laha i nā wahi ʻē aʻe o ke kino (e laʻa me ka iwi, ka māmā, ka ate) |
ʻO ka ʻike hoʻokūkū keu
Hiki i kāu kauka ke kamaʻilio e pili ana i kāu pae ma ka hoʻohana ʻana i kahi leka, e like me A,B, E, X a i ʻole S. Hāʻawi kēia mau leka i ka ʻike hou aku e pili ana i nā hōʻailona āu i loaʻa ai a i ʻole ka hopena o kou kino e ka lymphoma. Kōkua kēia ʻike a pau i kāu kauka e ʻimi i ka hoʻolālā lapaʻau maikaʻi loa no ʻoe.
palapala | Meaning | nui |
A a i ʻole B |
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|
E & X |
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S |
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(ʻO kou spleen he ʻōkana i loko o kāu ʻōnaehana lymphatic e kānana a hoʻomaʻemaʻe i kou koko, a he wahi ia e hoʻomaha ai kou mau cell B a hana i nā antibodies) |
Nā hoʻāʻo no ke kahua
No ka ʻike ʻana i ka pae āu e loaʻa ai, e noi ʻia paha ʻoe e loaʻa i kekahi o kēia mau hoʻokolohua staging:
Ka pākuʻina o ka tomography (CT)
Lawe kēia mau kiʻi i nā kiʻi o loko o kou umauma, ka ʻōpū a i ʻole ke pelvis. Hāʻawi lākou i nā kiʻi kikoʻī e hāʻawi i ka ʻike hou aku ma mua o kahi X-ray maʻamau.
ʻO ka ʻōmole helu Positron emoate (PET)
He scan kēia e kiʻi i nā kiʻi o loko o kou kino holoʻokoʻa. E hāʻawi ʻia ʻoe i kahi lāʻau lapaʻau e hoʻopaʻa ʻia ai nā cell cancerous - e like me nā cell lymphoma. ʻO ka lāʻau lapaʻau e kōkua ana i ka PET scan e ʻike i kahi o ka lymphoma a me ka nui a me ke ʻano ma ke kuhikuhi ʻana i nā wahi me nā cell lymphoma. Ua kapa ʻia kēia mau wahi he "wela".
Pahu lumbar
ʻO ka ʻoki ʻana i ka lumbar kahi hana e nānā ai inā loaʻa iā ʻoe kahi lymphoma i loko o kou ʻōnaehana ʻōnaehana waena (CNS), e pili ana i kou lolo, spinal cord a me kahi wahi a puni kou mau maka. Pono ʻoe e ʻōlelo mālie i ka wā o ke kaʻina hana, no laila e loaʻa i nā pēpē a me nā keiki kahi maʻi maʻi maʻamau e hoʻomoe iā lākou no kahi manawa liʻiliʻi e hana ʻia ai ke kaʻina hana. Pono ka hapa nui o ka poʻe mākua i kahi anesthetic kūloko no ke kaʻina hana e hoʻopau ai i ka wahi.
Na kāu kauka e hoʻokomo i ka nila ma kou kua, a e lawe i kahi wai liʻiliʻi i kapa ʻia ʻo "ka wai o ke kuamoʻo o ka lolo” (CSF) mai a puni kou iwi kuamoʻo. ʻO ka CSF kahi wai e hana like me ka mea hoʻopuʻi i kou CNS. Lawe pū ia i nā protein like ʻole a me nā maʻi e hakakā ana i nā cell immune e like me nā lymphocytes e pale i kou lolo a me ke kuamoʻo. Hiki nō hoʻi iā CSF ke kōkua i ka hoʻokahe ʻana i kekahi wai ʻē aʻe i loaʻa iā ʻoe i loko o kou lolo a i ʻole a puni kou iwi kuamoʻo e pale ai i ka pehu ʻana ma ia mau wahi.
A laila e hoʻouna ʻia ka laʻana CSF i ka pathology a nānā ʻia no nā hōʻailona o ka lymphoma.
Biopsy iwi ʻōiwi
- ʻO ka aspirate iwi iwi (BMA): lawe ʻia kēia hoʻāʻo ʻana i kahi wahi liʻiliʻi o ka wai i loaʻa ma ka hakahaka o ka iwi.
- ʻO ka iwi aspirate trepine (BMAT): lawe kēia ho'āʻo i kahi laʻana liʻiliʻi o ka ʻiʻo iwi iwi.
Hoʻouna ʻia nā laʻana i ka pathology kahi e nānā ʻia ai nā hōʻailona o ka lymphoma.
Hiki ke ʻokoʻa ke kaʻina hana no nā biopsies iwi iwi ma muli o kahi āu e mālama ai, akā e hoʻokomo pinepine ʻia kahi anesthetic kūloko e hoʻopau i ka wahi.
Ma kekahi mau haukapila, hiki ke hāʻawi ʻia iā ʻoe i ka hoʻomaha māmā e kōkua iā ʻoe e hoʻomaha a hiki ke kāpae iā ʻoe mai ka hoʻomanaʻo ʻana i ke kaʻina hana. ʻAʻole pono ka nui o ka poʻe i kēia a loaʻa paha i kahi "whistle green" e omo ai. He lāʻau hōʻeha ʻeha ko loko o kēia puʻupuʻu ʻōmaʻomaʻo (i kapa ʻia ʻo Penthrox a i ʻole methoxyflurane), āu e hoʻohana ai e like me ka mea e pono ai i ke kaʻina hana.
E hōʻoia ʻoe e nīnau i kāu kauka i nā mea i loaʻa e hōʻoluʻolu iā ʻoe i ka wā o ke kaʻina hana, a e kamaʻilio pū me lākou e pili ana i kou manaʻo he koho maikaʻi loa ia no ʻoe.
Hiki ke loaʻa ka ʻike hou aku e pili ana i nā biopsies iwi ma kā mākou ʻaoʻao pūnaewele ma aneʻi.
He ʻokoʻa ka ulu ʻana o kāu mau sela lymphoma, a ʻokoʻa ka nānā ʻana i nā cell maʻamau. ʻO ka pae o kāu lymphoma ka wikiwiki o ka ulu ʻana o kāu mau pūnaewele lymphoma – inā he molowa a ʻāʻī paha. ʻOi aku ka ikaika o kāu AITL, ʻoi aku ka ʻokoʻa o ka nānā ʻana i nā cell maʻamau.
ʻO nā papa he 1-4 (haʻahaʻa, waena, kiʻekiʻe). Inā loaʻa iā ʻoe kahi lymphoma kiʻekiʻe (ʻoi aku ka huhū), ʻokoʻa loa ke ʻano o kāu mau pūnaewele lymphoma mai nā pūnaewele maʻamau, no ka mea, ke ulu wikiwiki nei lākou e ulu pono. Aia ma lalo kahi ʻike o nā māka.
- G1 - papa haʻahaʻa - ke nānā aku nei kāu mau cell i kahi maʻamau, a ulu lākou a pālahalaha mālie.
- G2 – papa waena – ke hoʻomaka nei kāu mau cell e nānā ʻokoʻa akā aia kekahi mau cell maʻamau, a ulu a laha lākou ma kahi wikiwiki.
- G3 – papa kiʻekiʻe – ʻokoʻa ke ʻano o kāu mau cell me kekahi mau cell maʻamau, a ulu lākou a pālahalaha wikiwiki.
- G4 - papa kiʻekiʻe - ʻokoʻa loa kāu mau cell i ka mea maʻamau, a ulu a palahalaha loa lākou.
Hoʻohui kēia ʻike āpau i ke kiʻi holoʻokoʻa a kāu kauka i kūkulu ai e kōkua i ka hoʻoholo ʻana i ke ʻano o ka lāʻau lapaʻau maikaʻi loa no ʻoe.
He mea nui e kamaʻilio me kāu kauka e pili ana i kāu mau mea pilikia ponoʻī i hiki iā ʻoe ke ʻike maopopo i ka mea e manaʻo ai mai kāu mau lapaʻau.
Lapaʻau no ka Angioimmunoblastic Lymphoma (AITL)
Ke pau nā hualoaʻa mai ka biopsy a me nā scan staging, e nānā kāu kauka iā lākou e hoʻoholo i ka lāʻau lapaʻau maikaʻi loa no ʻoe.
Noʻonoʻo nā kauka i nā kumu he nui e pili ana i ka lymphoma a me ke olakino maʻamau o ka mea maʻi e hoʻoholo ai i ka wā a me ka lāʻau e pono ai. Hoʻokumu ʻia kēia ma:
- He aha ka subtype a me ka pae o AITL iā ʻoe.
- ʻO nā hōʻailona āu e loaʻa nei.
- Pehea kou kino e pili ana i ka lymphoma.
- ʻO kou makahiki.
- ʻO kou olakino a maikaʻi a me nā kūlana ʻē aʻe āu e mālama nei.
- ʻO kāu makemake no ka lapaʻau ʻana ke loaʻa iā ʻoe nā ʻike āpau e pono ai e hana i kahi koho ʻike.
ʻO ka lāʻau lapaʻau mua
ʻO ka manawa mua ʻoe e hoʻomaka ai i ka mālama ʻana no AITL ua kapa ʻia ʻo ia ka lāʻau lapaʻau mua. Kaomi ma nā poʻomanaʻo ma lalo nei e aʻo hou e pili ana i nā protocols lapaʻau.
ka lapaʻau laina mua maʻamau no AITL hiki ke komo:
- kua (cyclophosphamide, doxorubicin, vincristine a me prednisolone)
- CHOEP (CHOP me ka hoʻohui o ka etoposide)
- ʻO ka chemotherapy kiʻekiʻe a ukali ʻia e ka autologous stem cell transplant (ASCT)
- Ke komo ʻana i ka hoʻokolohua lapaʻau
ʻO ka laina ʻelua a me nā lāʻau lapaʻau ʻē aʻe
He nui ka poʻe i pane maikaʻi mai ka lāʻau lapaʻau mua a hele i ke kala ʻana. ʻO kēia kahi ʻaʻohe hōʻailona ʻike ʻia o ka lymphoma i koe i loko o kou kino. Akā he mea maʻamau no ka AITL e hoʻi mai ma hope o ka manawa i kala ʻia, kapa ʻia kēia he relapse.
I kekahi mau hihia, ʻaʻole maikaʻi paha kāu AITL me ka lāʻau lapaʻau mua. Inā loaʻa kēia, ʻōlelo ʻia kāu AITL he refractory (a ʻaʻole pane) i ka mālama ʻana.
Inā loaʻa iā ʻoe ka AITL refractory a ua hoʻi hou, pono ʻoe e hoʻomaka i kahi lapaʻau ʻē aʻe. Kapa ʻia kēia lāʻau lapaʻau ʻelua.
Hiki i nā lāʻau lapaʻau maʻamau ʻelua ke komo i kekahi o nā lāʻau lapaʻau mua a i ʻole:
- Romidepsin
- ʻO Pralatrexate
- ʻO ka chemotherapy kiʻekiʻe i ukali ʻia e ka hoʻololi ʻana i ke ʻano o nā pūnaʻi allogeneic
- ʻO ke kelepona
- Nā hoʻokolohua lapaʻau.
Nā hopena maʻamau o ka Lapaʻau
Nui nā hopena ʻaoʻao like ʻole o ka lāʻau lapaʻau a pili kēia i ka lāʻau i hāʻawi ʻia. Hiki i ke kauka lapaʻau a/a i ʻole kahu maʻi maʻi ke wehewehe i nā hopena ʻaoʻao kikoʻī ma mua o ka mālama ʻana. ʻO kekahi o nā hopena ʻaoʻao maʻamau o ka lāʻau lapaʻau hiki ke komo:
- Anemia (lawe nā koko ʻulaʻula haʻahaʻa i ka oxygen a puni ke kino)
- ʻO Thrombocytopenia (nā platelets haʻahaʻa e kōkua i ke koko a me ka cotting)
- ʻO Neutropenia (ke koko keʻokeʻo haʻahaʻa e kōkua i ka pale ʻana)
- ʻO ka naʻi a me ka luaʻi
- ʻO nā pilikia o ka ʻōpū e like me ka constipation a i ʻole ka maʻi maʻi
- Ka luhi - ka luhi a i ʻole ka nele o ka ikehu ʻaʻole maikaʻi me ka hoʻomaha a me ka hiamoe.
He aha ka wānana o AITL?
ʻO ka wānana o kahi maʻi e pili ana i ke ʻano o ka holomua ʻana, a me ke ʻano o ka pane ʻana i ka lāʻau lapaʻau.
I ka hapanui o nā hihia, pono ʻoe e hoʻomaka koke i ka mālama ʻana ma hope o kou loaʻa ʻana me AITL. ʻO kēia no ka mea maʻamau ia he subtype koʻikoʻi o ka lymphoma e laha koke a hoʻomāinoino iā ʻoe me ka mālama ʻole ʻana. I nā hihia koʻikoʻi loa, inā he subtype palaualelo kāu AITL, ʻaʻole pono ʻoe e hoʻomaka koke i ka mālama ʻana.
Aia kekahi mau mea pili i ka ma'i e pili ana i ka prognosis.
Nā kumu pākahi | Nā mea pili i ka maʻi |
makahiki ʻO ke olakino a me ke olakino holoʻokoʻa Pono nā maʻi ʻē aʻe a i ʻole ka lāʻau lapaʻau Hiki ke ʻae i ka lāʻau lapaʻau Nā makemake pilikino e pili ana i ka lāʻau lapaʻau | Subtype o AITL Pae a me ka papa o AITL Hoʻololi genetic Hōʻike ʻia i ka mālama ʻana ʻEhia mau manawa (a i ʻole nā laina) o kāu lapaʻau ʻana i ka wā ma mua |
He aha ka hana ma hope o ka mālama ʻana?
Makemake kāu kauka e ʻike mau iā ʻoe ma hope o ka pau ʻana o kāu mālama ʻana e nānā i kāu holomua a e hōʻoia ʻaʻole ʻoe i loaʻa nā hōʻailona o ka hoʻi hou ʻana, a i ʻole nā hopena hope.
Nā hopena hope
I kekahi manawa a hopena ʻaoʻao hiki ke hoʻomau a ulu paha nā mahina a i ʻole mau makahiki ma hope o ka pau ʻana o ka mālama ʻana. Kapa ʻia kēia he hopena hope. E hoʻomau kāu kauka i ka nānā ʻana iā ʻoe ma hope o kou hoʻopau ʻana i ka mālama ʻana e kiʻi i nā hopena hope loa i hiki ke mālama pono ʻia. ʻO ke ʻano o nā hopena hope loa e loaʻa iā ʻoe ma muli o ke ʻano o ka lapaʻau i loaʻa iā ʻoe.
E hōʻoia ʻoe e nīnau i kāu kauka i nā hopena hope loa e manaʻo ai a pehea a pehea ʻoe e hōʻike ai iā lākou.
Noho maikaʻi
ʻO ke ola olakino, a i ʻole kekahi mau loli ola maikaʻi ma hope o ka mālama ʻana he mea kōkua nui ia i kou ola hou ʻana. Nui nā mea hiki iā ʻoe ke hana e kōkua iā ʻoe e ola maikaʻi me AITL.
He nui ka poʻe i ʻike ma hope o ka hōʻoia ʻana i ka maʻi kanesa, a i ʻole ka mālama ʻana, e loli ana kā lākou mau pahuhopu a me nā mea nui i ke ola. ʻO ka ʻike ʻana i ke ʻano o kāu 'maʻamau hou' hiki ke hoʻolōʻihi i ka manawa a hoʻonāukiuki. He ʻokoʻa paha nā manaʻolana o kou ʻohana a me kou mau hoaaloha. Hiki paha iā ʻoe ke kaʻawale, luhi a i ʻole kekahi mau manaʻo like ʻole e loli i kēlā me kēia lā.
Nā pahuhopu ma hope o ka mālama ʻana
ʻO nā pahuhopu nui ma hope o ka mālama ʻana i kāu AITL ʻo ka hoʻi ʻana i ke ola a:
- e ʻeleu i kāu hana, ʻohana, a me nā kuleana ola ʻē aʻe
- e hoʻemi i nā hopena ʻaoʻao a me nā hōʻailona o ka maʻi kanesa a me ka mālama ʻana
- ʻike a mālama i nā hopena hope loa
- kōkua iā ʻoe e kūʻokoʻa e like me ka hiki
- hoʻomaikaʻi i kou maikaʻi o ke ola a mālama i ke olakino noʻonoʻo maikaʻi.
Hoʻoponopono i ka maʻi maʻi maʻi
Hiki ke hāʻawi ʻia iā ʻoe nā ʻano hoʻolaʻa maʻi kanesa. Hiki i kēia ke manaʻo i kekahi o ka laulā ākea o na lawelawe e like me:
- kino kino, hooponopono eha
- hoʻolālā meaʻai a me ka hoʻoikaika kino
- ka manaʻo, ka ʻoihana a me ke aʻo kālā.
hōʻuluʻulu manaʻo
- ʻO ka Angioimmunoblastic T-cell Lymphoma (AITL) he subtype o Peripheral T-cell Lymphoma - he ʻano o Non-Hodgkin Lymphoma.
- 'O AITL 'o ia ho'i ke 'ano o ka ma'i 'a'ai mai loko mai o nā pūna'i immune 'ole (T-cells) me nā kī'aha koko 'ano 'ole ma ke kahua o ka lymphoma.
- ʻO AITL ka mea maʻamau a pono e mālama koke ma hope o ka maʻi ʻana.
- Hiki i ka lapaʻau ke komo i ka chemotherapy, radiotherapy, immune therapies, i hoʻopaʻa ʻia a i ʻole ka hoʻololi ʻana i nā cell stem.
- Hiki paha iā ʻoe ke pane maikaʻi i kāu lapaʻau ʻana, akā ʻaʻole ia he mea maʻamau no ka AITL e hoʻi hou a makemake hou i ka lāʻau lapaʻau.
- Hōʻike i nā mea a pau nā hōʻailona, me B-hōʻailona i kāu kauka.
- E nīnau i kāu kauka e pili ana i ka mea e manaʻo ai mai kāu lapaʻau.
- E kelepona aku i kā mākou Lymphoma Care Nurses inā makemake ʻoe e kamaʻilio e pili ana i kāu lymphoma a i ʻole nā lāʻau lapaʻau iā ia - Kaomi ma ke pihi Hoʻokaʻaʻike iā mākou ma lalo o ka pale no nā kikoʻī.
