Dulmar guud ee Lymphoma-ka-beddelay (TL)
Lymphoma-da la beddeley waxay dhacdaa marka lymfoma-gaagu is-beddelo, oo ay noqoto lymfoma gardarro leh oo leh astaamo nooc-hoosaad ah oo ka duwan. Tani way ka duwan tahay lymphoma-gaaga indolent "kac" ama aad noqoto mid firfircoon oo u baahan daaweyn. Xaaladaha qaarkood, waxaa laga yaabaa inaad leedahay labadaba unugyo limfoma ah oo aan caajis ahayn iyo kuwa gardaran marka lymfoma ay marto habka isbeddelka.
Lymphomas-ka aan caajiska ahayn waxay caadi ahaan ka kooban yihiin unugyo yaryar oo si tartiib ah u koraya. Si kastaba ha ahaatee, haddii qaar badan oo ka mid ah unugyadan ay bilaabaan inay koraan weyn, oo si degdeg ah, lymfoma waxay bilaabataa inay u dhaqmaan sida lymphoma gardarrada ah sida Diffuse Large B-cell Lymphoma (DLBCL). Maaha wax aan caadi ahayn marka aad leedahay lymfoma oo is-bedeshay, in aad leedahay unugyo lymphoma ah oo isku dhafan, qaar waa kuwo aan caajis ahayn iyo kuwo kale oo dagaal badan.
Ujeedooyinka daawaynta lymfoma kaaga aan shaqaynayn ama is-bedeshay
Inta badan lymphomas-ka aan shaqayn waxay mari doonaan marxalado ay seexdaan oo ay ka soo kacaan. Si kastaba ha ahaatee, haddii lymfoma kaaga aan shaqaynayn ay noqoto mid firfircoon oo u baahan daaweyn, waxaad heli doontaa daawayn lagugu hagayo maaraynta lymfomaga aan shaqaynayn.
Si kastaba ha noqotee, haddii lymfoma-gaaga aan la daboolin beddelasho Nooc-hoosaadyada gardarrada ah ee lymfoma, waxay u badan tahay in lagugu daweynayo si aad u bogsato, ama lymphoma-ga gardarrada ah u gelinayso cafis.
Waa maxay sababta isbeddelku u dhaco?
Lymphoma waxay isbedeli kartaa marka unugyada lymphoma, ama hiddo-wadaha siiya tilmaamaha unugyadaada ay horumariyaan isbeddellada hidde-sideyaasha cusub. Isbeddelladan cusubi waxay noqon karaan natiijada daawayntii hore ee kansarka ka hortagga, ama waxay dhici kartaa iyadoon la garanayn sabab la garanayo. Isbeddellada hidde-sidaha ayaa beddeli kara habka lymfamadu u korto oo ay u dhaqanto, taasoo keenta dabeecad dagaal badan.
Yaa uu saameeyay Lymphoma-ka-beddelashada?
Qof kasta oo qaba lymfoma-hooseeya ama lymfoma indolent wuxuu halis ugu jiraa isbeddel. Si kastaba ha ahaatee aad ayay dhif u tahay, oo kaliya waxay ku dhacdaa qiyaastii 1 ilaa 3 qof 100kiiba qof oo qaba lymphoma indolent sanad walba (1-3%).
Waxaad yeelan doontaa in yar oo khatar ah oo isbeddel ah haddii aad leedahay cudur weyn (buro weyn ama burooyin) marka ugu horraysa ee lagaa helo lymphomaga aan shaqaynayn.
Lymphoma-yada ugu caansan ee is-beddeli kara waxaa ka mid ah B-cell lymphoma sida:
- Lymphoma follicular ah
- Lymphocytic Leukemia ama unug yar oo Lymphoma ah
- Lymphoma Aagga Margin
- Nodular Lymphocyte Predominant B-cell Lymphoma (hore loo yaqaanno Nodular Lymphocyte Predominant Hodgkin Lymphoma)
- Lymphoma unug Mantle ah oo aan shaqayn
- Waldenstrom's Macroglobulinemia
Waxaa muhiim ah in la fahmo in badi dadka qaba lymphomas aysan isbeddelin.
Dadka qaarkiis oo qaba qanjidhada T-cell-ka ee aan fiicnayn ayaa sidoo kale laga yaabaa inay isbeddelaan, laakiin kuwani xitaa waa dhif.
Goorma ayay u badan tahay in isbeddelku dhaco?
Lymphoma oo la beddelo waxay dhici kartaa wakhti kasta, laakiin waxay u badan tahay inaad isbeddel ku yeelato qiyaastii 3-6 sano ka dib marka lagugu ogaado lymphoma-gaaga aan shaqaynayn.
Khatarta isbeddelku aad bay u yaraanaysaa ka dib markaad la noolaato lymfomaga aan shaqaynayn muddo 15 sano ah, iyadoo isbeddellada wakhtigan ka dib ay aad dhif u yihiin.
Calaamadaha taasi waxay muujin kartaa in lymphomaagu is-beddelay
Waxa kale oo laga yaabaa inaad hesho calaamadaha B-ka marka lymphomaagu uu noqdo mid firfircoon ama uu bilaabo inuu isbeddelo
Waa maxay isbeddellada ugu badan?
Isbeddellada qaarkood ayaa aad ugu badan kuwa kale. Hoos waxaan ku taxnay isbeddellada caadiga ah (inkasta oo ay naadir yihiin) ee dhici kara.
Lymphoma oo aan sal lahayn |
Waxay isu beddeli kartaa lymphoma soo socda |
| Lymphocytic Leukemia/Lymphoma-yar oo Lymphocytic ah (CLL/SLL) |
U beddelo unug weyn oo B-cell Lymphoma (DLBCL) - isbeddelkan waxaa loo yaqaanaa Richter syndrome. Si aad u naadir ah, CLL/SLL waxay isu beddeli karaan nooc-hoosaadka qadiimiga ah ee Hodgkin Lymphoma. |
| Lymphoma follicular ah |
Isbeddelka ugu caansan waa in la faafiyo Large B-cell Lymphoma (DLBCL). Marar dhif ah, waxay isu beddeshaa lymfoma B-cell oo dagaal leh, oo leh astaamo DLBCL iyo Burkitt Lymphoma labadaba. |
| Lymphomasmacytic Lymphoma (sidoo kale loo yaqaan Waldenstrom macroglobulinemia) | Faafi Large B-cell Lymphoma (DLBCL). |
| Unugyada Mantle Lymphoma (MCL) | Blastic (ama blastoid) MCL. |
| Lymphomas Aagga Marginal (MZL) | Faafi Large B-cell Lymphoma (DLBCL). |
| Unugyada Lymphoid-ka ee xuubka-isku-xidhan ee Lymphoma (MALT), nooc-hoosaadka MZL | Faafi Large B-cell Lymphoma (DLBCL). |
| Nodular Lymphocyte-B-unugyada ugu badan Lymphoma (oo hore loogu yeeri jiray Nodular Lymphocyte-Predominant Hodgkin lymphoma) | Diffous Large B-cell Lmphoma (DLBCL). |
| Cudurka loo yaqaan 'T-cell Lymphoma' (CTCL) | Lymphoma unug weyn. |
Cilad-sheegidda iyo habaynta Lymphoma-ka-beddelay
Haddii dhakhtarkaagu uu ka shakiyo in lymphomaagu ay is beddeshay waxay rabi doonaan inay sameeyaan baadhitaano iyo baaritaanno dheeraad ah. Tijaabooyinku waxa ay ku jiri doonaan biopsi si loo hubiyo in unugyada lymphoma ay sameeyeen isbeddello cusub, iyo haddii ay hadda u dhaqmayaan sidii nooc ka duwan oo lymphoma ah, iyo baarista ayaa noqon doonta heerka lymfoma.
Baadhitaannadan iyo baaristan waxay la mid noqonayaan kuwii lagugu arkay markii ugu horreysay ee lagaa helay lymphoma. Macluumaadka kuwan ayaa ku siin doona dhakhtarkaaga macluumaadka loo baahan yahay si ay kuu siiyaan nooca ugu fiican ee daaweynta lymphoma-gaaga is-beddelay.
Daaweynta
Marka dhammaan natiijooyinkaaga ka soo-baxa ka-qaadista iyo baadhista diyaarinta la dhammeeyo, dhakhtarkaaga ayaa dib u eegi doona si uu u go'aamiyo daawaynta ugu fiican ee suurtogalka ah ee adiga. Dhakhtarkaagu waxa kale oo laga yaabaa inuu la kulmo koox kale oo takhasus leh si uu ugala hadlo daaweynta ugu fiican taasna waxaa loo yaqaan a kooxda culuumta badan (MDT) kulan.
Dhakhtarkaagu wuxuu tixgelin doonaa arrimo badan oo ku saabsan lymphoma kaaga iyo caafimaadkaaga guud si uu u go'aansado haddii, iyo daaweynta loo baahan yahay. Waxyaabaha ay ka fiirsan doonaan waxaa ka mid ah:
- Waa maxay isbeddelka dhacay (noocaaga cusub ee lymphoma)
- Marxaladda lymphoma
- Calaamad kasta oo aad isku aragto
- Sida lymfoma ay u saamayso jidhkaaga
- Dadaada
- Dhibaatooyin kale oo caafimaad oo aad qabto ama daawooyinka aad qaadanayso
- Dookhyadaada marka aad hesho dhammaan macluumaadka aad u baahan tahay.
Noocyada Daawaynta
Lymphoma la beddelo waxay u baahan tahay in loo daweeyo si la mid ah sida lymfoma gardarrada ah. Daaweynta waxaa ka mid noqon kara:
- Isku darka kemotherabi
- Antibiyootiko Monoclonal
- Qalliinka unugyada unugyada 'autologous transplant cell' (haddii caafimaad ku filan yahay)
- Rotooterapi (sida caadiga ah kiimoterabiga)
- CAR T-cell daaweynta (Daawaynta unugyada T-cell ee Chimeric antigen - ka dib 2 daawayn hore)
- immunotherapy
- Daawaynta la beegsaday
- Ka qayb qaadashada tijaabada caafimaadka
Saadaasha Lymphoma Isbadashay (TL)
Lymphomas badan oo qallafsan ayaa la daweyn karaa, ama waxay yeelan karaan waqtiyo dheer oo cafis ah ka dib daaweynta. Sidan oo kale, waxaa jirta rajo ah in marka daawaynta lagu siiyo laga yaabo in lagu bogsado, ama lagaa cafiyo lymphoma-da gardarada badan, oo beddeshay. Si kastaba ha ahaatee, waxaad weli u baahan doontaa dabagal dhow ka dib daaweyntaada si aad u hubiso calaamadaha soo noqoshada.
Lymphomas-xumada inta badan lama daweyn karo, sidaas darteed xitaa ka dib daawaynta lymfoma-gaaga is-beddelay, waxaa laga yaabaa inaad weli harsan tahay qaar ka mid ah unugyada lymphoma ee aan shaqaynayn, sidaas awgeedna dhakhtarkaagu wuxuu doonayaa inuu sidoo kale hubiyo tan.
Waydii dhakhtarkaaga fursadaha aad ku bogsanayso, aad galayso cafiska oo aad wali la nooshahay limfoma aan shaqaynayn ka dib daawaynta lymfoma-gaaga is beddeshay.
Summary
- Lymphoma oo la beddelo aad bay naadir u tahay, iyadoo keliya 1-3 ka mid ah 100kii qof ee qaba lymfoma indolent ay isbeddelaan sannad kasta.
- Beddelku wuxuu ku badan yahay dadka qaba lymphoma B-cell, laakiin waxay ku dhici kartaa dadka qaba lymphoma T-cell aan shaqaynayn.
- Isbeddelku waa caadi 3-6 sano ka dib marka lagugu ogaado lymphoma aan shaqaynayn, aadna aad ayay dhif u tahay 15 sano ka dib.
- Lymphoma oo beddeshay waxay dhici kartaa haddii hiddo-wadahaaga ama unugyada lymphoma ay horumariyaan isbeddello cusub, beddelaan habka lymphoma u koraan iyo u dhaqmaan.
- Lymphoma oo beddeshay way ka duwan tahay lymfoma aan shaqaynayn "kac" oo noqota mid firfircoon.
- Weli waxaa jirta suurtagal ah in laga bogsado lymfoma-da qallafsan ee is-bedeshay, laakiin waxaad sii wadi kartaa inaad la noolaato lymfoma-da aan la dhayalsaneyn daaweynta ka dib.
- Daawaynta lymfoma-badashay waxa lagu bartilmaameedsan doonaa in la daweeyo, ama la geliyo lymfoma gardarrada ah oo laga saaro.
- Ka warbixi wax kasta oo cusub oo ka sii daraya calaamadaha, oo ay ku jiraan B-calaamadaha dhakhtarkaaga.
