Uhlolojikelele I-Peripheral T-cell Lymphoma (PTCL)
I-Peripheral T-cell lymphoma (PTCL) yigama elinikezwa iqembu lama-Non-Hodgkin lymphomas anamandla (akhula ngokushesha) aqala lapho uhlobo lwengqamuzana elimhlophe legazi libizwa. T-cell lymphocyte abe nomdlavuza. Ama-T-cell enziwa emnkantsheni wethu wamathambo, kodwa ahamba ngohlelo lwethu lwe-lymphatic aye ku-thymus yethu lapho eqhubeka nokukhula futhi athuthuke.
Mayelana namaseli e-NK & T-cell Lymphocyte
- Amaseli e-Natural Killer (NK) avame ukubizwa "NK T-cells". Amangqamuzana omzimba akhethekile aqaphela futhi acekele phansi amangqamuzana omdlavuza. Ngokungafani namanye ama-T-cell, amaseli e-NK awadingi ukuthi acushwe ukuze alwe nomdlavuza. Bakulungele ukulwa nomdlavuza ngaso sonke isikhathi, futhi banyakaze ngenkuthalo umzimba wakho bebheka amangqamuzana anezinguquko zomdlavuza.
- Amanye ama-T-cell adinga ukwenziwa asebenze ukuze asebenze ngempumelelo. Ngokuvamile ziphumula ku-thymus yakho, ama-lymph nodes noma ezinye izingxenye zesistimu yakho ye-lymphatic, futhi zivuka kuphela futhi zilwe nokutheleleka lapho amanye amangqamuzana omzimba ewazisa ukuthi kukhona ukutheleleka noma isifo okufanele silwe. Lapho evuka, ama-T-cell angahambela kunoma iyiphi ingxenye yomzimba wakho ukuze alwe negciwane noma isifo.
- Amanye ama-T-cell anesibopho "sokulawula" impendulo yokuzivikela komzimba. Lokhu kusho ukuthi uma ukutheleleka sekubhujisiwe, i “Ama-T-cells alawulayo” tshela amanye amangqamuzana omzimba ukuthi “ame phansi” ukuze angaqhubeki elwa futhi abangele ukulimala kumaseli akho amahle uma isifo sesiphelile.
- Ngemva kokulwa nokutheleleka noma isifo, amanye ama-T-cell aba "Memory T-cells" futhi bakhumbula yonke into ekhona mayelana nalesi sifo nokuthi singalwa kanjani naso. Ngaleyo ndlela, uma kwenzeka uphinde uthole ukutheleleka okufanayo noma isifo, amasosha akho omzimba angalwa naso ngokushesha okukhulu nangempumelelo.
Ama-T-cell kanye ne-Peripheral T-cell Lymphoma (PTCL)
I-PTCL iqala lapho amanye amaseli akho e-NK, noma amanye ama-T-cell eba nomdlavuza. Asazi ukuthi kungani lokhu kwenzeka kwabanye abantu, kodwa siyazi ukuthi ushintsho lwenzeka ezakhini zofuzo zakho ezinikeza imiyalelo yokuthi amaseli kufanele akhule futhi enze kanjani. Uma lolu shintsho lwenzeka amangqamuzana asuke engasatholi imiyalelo efanele, bese eqala ukukhula ngokushintshashintsha kwawo okubangela ukuthi akhule ngendlela engalawuleki, ashintshe angabe esakwazi ukwenza umsebenzi wawo wokulwa nezifo kanye nokutheleleka ngegciwane. impilo ngendlela efanele.
I-Peripheral T-cell lymphoma (PTCL) ingathinta abantu banoma iyiphi iminyaka kuhlanganisa nezingane, kodwa ivame kakhulu kubantu abaneminyaka engaphezu kwengama-60.
Ukuze uthole ulwazi olwengeziwe mayelana nokuthi kungani i-lymphoma iqala chofoza isixhumanisi esingezansi.
Izinhlobo ezingaphansi ze-PTCL
Cishe umuntu oyedwa kwabayi-1 abane-lymphoma uzoba nohlobo oluncane lwe-PTCL, nokho kunezinhlobo eziningi ezahlukene ze-PTCL okwenza ngayinye ibe yivelakancane kakhulu. Yize kunezinhlobo eziningi ezihlukene ze-PTCL, zingahlukaniswa ngokujwayelekile ngokuthi:
- UNodal: ukuqala kuma-lymph nodes akho noma ohlelweni lwe-lymphatic
- I-Extra-nodal: ukuqala ngaphandle kwama-lymph nodes kuhlanganise nezitho noma esikhunjeni sakho
- I-leukemic: iqala egazini noma emathanjeni akho
Uma usuwazi uhlobo lwakho oluncane lwe-PTCL futhi ungathanda ulwazi oluthile oluthile, chofoza ichashazi elingezansi ukuze uxhume kulelo khasi. Uma ungakalwazi uhlobo lwakho oluncane, noma ungalutholi olwakho ngezansi, qhubeka ufunda kuleli khasi ukuze uthole ulwazi olujwayelekile nge-PTCL.
- I-Peripheral T-cell lymphoma - ayicaciswanga ngenye indlela (PTCL-NOS)
- I-Angioimmunoblastic T-cell lymphoma (AITL)
- I-Anaplastic big cell lymphoma (ALCL)
- I-T-cell lymphoma yamathumbu
- I-Enteropathy-Type T-Cell Lymphoma (EATL)
- I-Monomorphic epitheliotropic lymphoma yamathumbu (MEITL)
- I-Nasal NK/T-Cell Lymphoma (NKTCL)
- I-Hepatosplenic gamma delta T-cell lymphoma
- I-Cutaneous T-cell Lymphoma (CTCL)
- I-Sezary Syndrome
- I-T-Cell Yabantu Abadala I-Leukemia/Lymphoma (ATLL)
- I-T-cell lymphoblastic lymphoma (LL)
Izindaba zokubekezela
The izimpawu okutholayo kungancika ohlotsheni oluncane lwe-PTCL onalo, nokuthi ikuphi emzimbeni wakho i-lymphoma. Ngokuvamile, uphawu yiqhubu eliphuma ngaphansi kwesikhumba sakho entanyeni, ekhwapheni noma enqeni ongakwazi ukulibona noma ukulizwa. Lokhu kubangelwa ukuvuvuka kwe-lymph node njengoba igcwala amaseli e-lymphoma anomdlavuza.
Ezinye izimpawu zingabandakanya:
- Ukulahlekelwa kwesifiso
- Ukuphelelwa umoya
- Ukungakhululeki kwesisu noma isisu noma ubuhlungu
- Ubuhlungu
- Ukukhathala
- Isikhumba esinamahloni
- B-izimpawu
Kubalulekile ukukhuluma nodokotela wakho nganoma yiziphi izimpawu ozitholayo ngoba ngezinye izikhathi izimpawu zakho zingasiza udokotela wakho ukuthi akubekele uhlobo olungcono kakhulu lokwelashwa. Ungathola ulwazi olwengeziwe ngezimpawu ze-lymphoma ngokuchofoza isixhumanisi esingezansi.
Ukuxilongwa kwe-PTCL, ukuhlelwa kanye nokugreda
Ukuhlonza i-PTCL ngezinye izikhathi kungase kube nzima futhi kungathatha amasonto ambalwa.
Uma udokotela wakho ecabanga ukuthi ungase ube ne-lymphoma, uzodinga ukuhlela inani lokuhlolwa okubalulekile. Lezi zivivinyo ziyadingeka ukuze uqinisekise noma ukhiphe i-lymphoma njengembangela yezimpawu zakho. Ngenxa yokuthi kunezinhlobo ezimbalwa ezihlukene ze-PTCL, ungase ube nezivivinyo ezengeziwe ukuze uthole ukuthi iyiphi onayo. Lokhu kubalulekile ngoba ukuphathwa nokuphathwa kohlobo lwakho oluncane kungase kwehluke kwezinye izinhlobo ezincane ze-PTCL.
Ukuze uhlole i-PTCL uzodinga i-biopsy. I-biopsy iyinqubo yokukhipha ingxenye, noma yonke i-lymph node ethintekile kanye/noma isampula yomnkantsha. I-biopsy ibe isihlolwa usosayensi we-pathology ukuze kubonakale ukuthi azikho yini izinguquko ezisiza udokotela ahlonze i-PTCL.
Uma wenza i-biopsy, ungase ube ne-anesthesia yendawo noma evamile. Lokhu kuzoncika ohlotsheni lwe-biopsy nokuthi ithathwe kuyiphi ingxenye yomzimba wakho. Kunezinhlobo ezahlukene ze-biopsies futhi ungase udinge ezingaphezu kweyodwa ukuze uthole isampula engcono kakhulu.
Ukuhlolwa kwegazi
Ukuhlolwa kwegazi kuthathwa uma uzama ukuxilonga i-lymphoma yakho, kodwa futhi kukho konke ukwelashwa kwakho ukuze uqiniseke ukuthi izitho zakho zisebenza kahle futhi zingakwazi ukubhekana nokwelashwa kwethu.
I-Core or fine inaliti biopsy
Ama-biopsies yenaliti angumongo noma amahle athathwa ukuze kukhishwe isampula ye-lymph node evuvukile, isimila noma isikhumba esithintekile ukuze kuhlolwe izimpawu ze-PTCL.
Udokotela wakho ngokuvamile uzosebenzisa isibulali-zinzwa sendawo ukuze enze indawo ibe ndikindiki ukuze ungezwa zinhlungu phakathi nenqubo, kodwa uzobe uphapheme phakathi nalokhu biopsy. Bazobe sebefaka inaliti ku-lymph node evuvukele noma isigaxa bese bekhipha isampula lesicubu.
Uma i-lymph node yakho evuvukele noma isigaxa sijule ngaphakathi emzimbeni wakho i-biopsy ingenziwa ngosizo lwe-ultrasound noma i-x-ray ekhethekile (imaging).
Ungase ube nesibulali-zinzwa esivamile salokhu (okukwenza ulale isikhashana). Ungase futhi ube nezitishi ezimbalwa kamuva.
I-Core Need biopsy ithatha isampula enkulu kune-finenes biopsy.
I-Excisional node biopsy
Ama-excisional node biopsies enziwa lapho i-lymph node yakho evuvukele noma isimila sijule kakhulu emzimbeni wakho ukuthi singafinyelelwa ngomongo noma ngenaliti ecolekile. Uzothola isibulali-zinzwa esivamile esizokulalisa isikhashana ukuze uhlale unganyakazi, futhi ungezwa buhlungu.
Phakathi nale nqubo, udokotela ohlinzayo uzokhipha yonke i-lymph node noma isigaxa futhi ayithumele ku-pathology ukuze ihlolwe.
Uzoba nenxeba elincane elinemithungo embalwa, kanye nengubo ngaphezulu.
Imithungo ivamise ukuhlala izinsuku eziyisi-7-10, kodwa udokotela noma unesi wakho uzokunikeza imiyalelo yokuthi unakekele ukugqokwa, nokuthi ubuya nini ukuyokhipha imithungo.
Sifo
Isiteji
Ukubamba
Ukutholakala kwe-peripheral T-cell lymphoma (PTCL)
Uma ukuxilongwa kwakho kwe-PTCL sekuqinisekisiwe uba nokuhlolwa okwengeziwe ukuze ubone ukuthi zingaki izindawo zomzimba wakho ezithintwa i-lymphoma. Lokhu kubizwa ngesiteji.
Isiteji sisho ukuthi ungakanani umzimba wakho othintwa i-lymphoma yakho - noma, ukuthi isisabalele kangakanani lapho iqale khona.
Ama-T-cell angahamba aye kunoma iyiphi ingxenye yomzimba wakho. Lokhu kusho ukuthi amaseli e-lymphoma (ama-T-cell anomdlavuza), angaphinde ahambe kunoma iyiphi ingxenye yomzimba wakho. Kuzodingeka wenze izivivinyo ezengeziwe ukuze uthole lolu lwazi. Lezi zivivinyo zibizwa ngokuthi yi-staging test futhi uma uthola imiphumela, uzothola ukuthi unesigaba sokuqala (I), isigaba sesibili (II), isigaba sesithathu (III) noma isigaba sesine (IV) PTCL.
Isigaba sakho se-PTCL sizoncika kulokhu:
- Zingaki izindawo zomzimba wakho ezine-lymphoma.
- Lapho i-lymphoma ihlanganisa uma ingaphezulu, ngezansi noma nhlangothi zombili ze-diaphragm yakho (umsipha omkhulu, omise okwedome ngaphansi kwezimbambo ohlukanisa isifuba nesisu sakho).
- Ukuthi i-lymphoma isisabalele kumnkantsha wakho wethambo noma ezinye izitho ezinjengesibindi, amaphaphu, isikhumba noma ithambo.
Izigaba I no-II zibizwa ngokuthi 'isigaba sokuqala noma esilinganiselwe' (okubandakanya indawo elinganiselwe yomzimba wakho).
Izigaba III kanye ne-IV zibizwa ngokuthi 'isiteji esithuthukisiwe' (sabalale kakhulu).
1 internship | indawo eyodwa ye-lymph node iyathinteka, noma ngaphezulu noma ngaphansi kwe-diaphragm* |
2 internship | izindawo ezimbili noma ngaphezulu zama-lymph node zithinteka ohlangothini olulodwa lwe-diaphragm* |
3 internship | okungenani indawo eyodwa ye-lymph node ngaphezulu kanye ne-lymph node eyodwa engaphansi kwe-diaphragm* iyathinteka |
4 internship | i-lymphoma itholakala kuma-lymph nodes amaningi futhi isisakazekele kwezinye izingxenye zomzimba (isb. amathambo, amaphaphu, isibindi) |
Ulwazi lwesiteji olwengeziwe
Udokotela wakho angase futhi akhulume ngesiteji sakho esebenzisa incwadi, efana no-A,B, E, X noma S. Lezi zincwadi zinikeza ulwazi olwengeziwe mayelana nezimpawu onazo noma ukuthi umzimba wakho uthinteka kanjani i-lymphoma. Lonke lolu lwazi lusiza udokotela wakho ukuthi akutholele uhlelo olungcono kakhulu lwezokwelapha.
Incwadi | Okusho | Ukubaluleka |
A noma B |
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E & X |
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S |
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(Ubende lwakho luyisitho ohlelweni lwakho lwe-lymphatic oluhluza futhi luhlanze igazi lakho, futhi luyindawo lapho ama-B-cell akho aphumula khona futhi enze amasosha omzimba) |
Ukuhlolwa kwesiteji
Ukuze uthole ukuthi yisiphi isigaba onaso, ungacelwa ukuthi wenze ezinye zalezi zivivinyo ezilandelayo:
Icwecwe le-computer tomography (CT)
Lezi zithwebuli zithatha izithombe zengaphakathi lesifuba sakho, isisu noma i-pelvis. Banikeza izithombe ezinemininingwane enikeza ulwazi olwengeziwe kune-X-ray evamile.
Ukuskena kwe-Positron emission tomography (PET)
Lesi iskena esithatha izithombe zengaphakathi lomzimba wakho wonke. Uzonikezwa futhi ufake inaliti ngomuthi othile othathwa amaseli anomdlavuza - njengamaseli e-lymphoma. Umuthi osiza ukuskena kwe-PET ukukhomba lapho i-lymphoma ikuphi kanye nosayizi nokuma ngokugqamisa izindawo ezinamaseli e-lymphoma. Lezi zindawo ngezinye izikhathi zibizwa ngokuthi "ezishisayo".
Ukukhishwa kwe-Lumbar
Ukubhoboza i-lumbar kuyinqubo eyenziwa ukuhlola ukuthi unayo yini i-lymphoma endaweni yakho isimiso sezinzwa esiyinhloko (CNS), okuhlanganisa ubuchopho bakho, umgogodla kanye nendawo ezungeze amehlo akho. Uzodinga ukuthi unganyakazi phakathi nenqubo, ukuze izingane kanye nezingane zibe nesibulali-zinzwa esivamile ukuze zilalise isikhashana inqubo yenziwa. Abantu abadala abaningi bazodinga kuphela umuthi obulala izinzwa wasendaweni ukuze inqubo iqede indawo.
Udokotela wakho uzokufaka inaliti emhlane wakho, futhi akhiphe uketshezi oluncane olubizwa ngokuthi “uketshezi lwe-cerebral spinal” (CSF) kusuka eduze komgogodla wakho. I-CSF iwuketshezi olusebenza kancane njengesibambisi sokwethuka ku-CNS yakho. Iphinde ithwale amaprotheni ahlukene kanye nokutheleleka okulwa namaseli omzimba afana ne-lymphocyte ukuvikela ubuchopho bakho nomgogodla. I-CSF ingasiza futhi ukukhipha noma iluphi uketshezi olwengeziwe okungenzeka unalo ebuchosheni bakho noma eduze komgogodla wakho ukuvimbela ukuvuvukala kulezo zindawo.
Isampula ye-CSF izobe isithunyelwa ku-pathology futhi ihlolwe noma yiziphi izimpawu ze-lymphoma.
I-bone yomnkantsha i-biopsy
- I-Bone marrow aspirate (BMA): lokhu kuhlola kuthatha inani elincane loketshezi olutholakala endaweni yomnkantsha.
- I-Bone marrow aspirate trephine (BMAT): lokhu kuhlola kuthatha isampula elincane lomnkantsha wethambo.
Amasampula abe esethunyelwa ku-pathology lapho ehlolelwa khona izimpawu ze-lymphoma.
Inqubo ye-biopsies yomnkantsha ingahluka kuye ngokuthi ulashwa kuphi, kodwa ngokuvamile izofaka isibulali-zinzwa sasendaweni ukuze ndikindiki indawo.
Kwezinye izibhedlela, ungase unikezwe i-sedation elula ekusiza ukuthi uphumule futhi ingakuvimba ekukhumbuleni inqubo. Nokho abantu abaningi abakudingi lokhu futhi esikhundleni salokho bangase babe “nempempe eluhlaza” abangayincela. Le nlozi eluhlaza inomuthi obulala izinhlungu kuwo (obizwa ngePenthrox noma i-methoxyflurane), owusebenzisa njengoba kudingeka kuyo yonke inqubo.
Qiniseka ukuthi ubuza udokotela wakho ukuthi yini etholakalayo ukuze ukhululeke kakhudlwana phakathi nenqubo, futhi ukhulume nabo ngalokho ocabanga ukuthi kuyoba inketho engcono kakhulu kuwe.
Ulwazi olwengeziwe mayelana nama-biopsies omnkantsha lungatholakala ekhasini lethu lewebhu lapha.
Amaseli akho e-lymphoma anephethini yokukhula ehlukile, futhi abukeka ehlukile kumaseli avamile. Ibanga le-lymphoma yakho yindlela amaseli e-lymphoma akhula ngayo ngokushesha - kungakhathaliseki ukuthi ayivilapha noma inolaka. Uma i-PTCL yakho iba nolaka, izobukeka ihluke kakhulu kumaseli avamile.
Amabanga amabanga 1-4 (aphansi, aphakathi nendawo, aphezulu). Uma une-lymphoma yebanga eliphezulu (enolaka), amaseli e-lymphoma azobukeka ehluke kakhulu kumaseli avamile, ngoba akhula ngokushesha kakhulu ukuze athuthuke kahle. Uhlolojikelele lwamabanga lungezansi.
- I-G1 – ibanga eliphansi – amaseli akho abukeka esondele kokujwayelekile, futhi akhula futhi asakazeke kancane.
- I-G2 - ibanga eliphakathi nendawo - amaseli akho aqala ukubukeka ehlukile kodwa amanye amaseli avamile akhona, futhi akhula futhi asakazeke ngesilinganiso esimaphakathi.
- I-G3 - ibanga eliphezulu - amaseli akho abukeka ehluke kakhulu ngamaseli ambalwa avamile, futhi akhula futhi asakazeke ngokushesha.
- I-G4 – ibanga eliphezulu – amaseli akho abukeka ehluke kakhulu kokujwayelekile, futhi akhula futhi asakazeke ngokushesha.
Lonke lolu lwazi lwengeza kuso sonke isithombe esakha udokotela wakho ukusiza ukunquma uhlobo olungcono kakhulu lokwelashwa kwakho.
Kubalulekile ukuthi ukhulume nodokotela wakho mayelana nezici zakho eziyingozi ukuze ube nombono ocacile wokuthi yini ongayilindela ekwelashweni kwakho.
Ukwelashwa kwe-peripheral T-cell lymphoma (PTCL)
Uma yonke imiphumela evela ku-biopsy kanye nezikena zesiteji seziqediwe, udokotela wakho uzoyibuyekeza ukuze anqumele ukwelashwa okungcono kakhulu ongakuthola.
Odokotela bacabangela izici eziningi mayelana ne-lymphoma kanye nempilo evamile yesiguli ukuze banqume ukuthi nini futhi yikuphi ukwelashwa okudingekayo. Lokhu kusekelwe kokuthi:
- Iluphi uhlobo oluncane kanye nesigaba se-PTCL onaso.
- Noma yiziphi izimpawu ozitholayo.
- Ukuthi umzimba wakho uthinteka kanjani i-lymphoma.
- Iminyaka yakho.
- Impilo yakho jikelele kanye nokuphila kahle kanye nanoma yiziphi ezinye izimo owelashelwa zona.
- Izinketho zakho zokwelashwa uma usunalo lonke ulwazi oludingekayo ukuze ukhethe unolwazi.
Ukwelashwa komugqa wokuqala
Isikhathi sokuqala uma uqala ukwelashwa kwe-PTCL kubizwa ngokuthi ukwelashwa komugqa wokuqala. Chofoza izihloko ezingezansi ukuze ufunde kabanzi mayelana nezinqubo zokwelapha.
The ukwelashwa okujwayelekile komugqa wokuqala ye-PTCL ingafaka:
- CHOP (i-cyclophosphamide, i-doxorubicin, i-vincristine ne-prednisolone)
- KHETHA (CHOP kanye nokwengezwa kwe-etoposide)
- I-BV-CHP (Brentuximab Vedotin, cyclophosphamide, doxorubicin, prednisone)
- SMILE - Okwe-NK T-cell lymphoma kuphela (i-methotexate, i-calcium folinate, i-dexamethasone, i-etoposide, i-ifosphamide, i-mesna, i-GCSF, i-asparaginase)
- I-DDGP - Okwe-NK T-cell lymphoma kuphela (i-dexamethasone, i-pegasparaginase, i-gemcitabine, i-cisplatin, i-GCSF)
- I-chemotherapy enedosi ephezulu elandelwa yi-autologous stem cell transplant (ASCT)
- Radiotherapy
- Ukubamba iqhaza kokuhlolwa komtholampilo
Umugqa wesibili kanye nezinye izindlela zokwelapha
Abantu abaningi banokusabela okuhle ekwelashweni komugqa wokuqala futhi bazoya eshweni. Lokhu lapho kungekho sibonakaliso esibonakalayo se-lymphoma esisele emzimbeni wakho. Kodwa kuvamile ukuthi i-PTCL ibuye ngemva kwesikhathi sokuxolelwa, lokhu kubizwa ngokuthi ukuphindukuzalwa.
Kwezinye izimo, i-PTCL yakho ingase ingabi ngcono ngokwelashwa komugqa wokuqala. Uma lokhu kwenzeka, i-PTCL yakho kuthiwa ayifuni (noma ayiphenduli) ekwelashweni.
Uma une-PTCL ye-refractory noma uphinde wabuyela emuva, uzodinga ukuthi uqale ukwelashwa okuhlukile. Lokhu kwelashwa okulandelayo kubizwa ngokuthi ukwelashwa komugqa wesibili.
Ukwelashwa okujwayelekile komugqa wesibili kungabandakanya kanye nokwelashwa komugqa wokuqala noma:
- I-Romidepsin
- I-Pralatrexate
- I-chemotherapy enedosi ephezulu elandelwa yi-allogeneic stem cell transplant
- I-Vorinostat - Nge-PTCL yesikhumba kuphela
- Ukuhlolwa komtholampilo.
I-prognosis ye-peripheral T-cell lymphoma (PTCL)
I-prognosis yindlela olindeleke ukuba usabele kahle ngayo ekwelashweni kwe-PTCL nokuthi umphumela uzoba yini. Ukubikezela kwakho kuyinto yomuntu ngamunye futhi kuncike ezintweni eziningana ezifana nalezi:
- uhlobo oluncane lwe-PTCL onayo kanye nesiteji sayo
- iminyaka yakho kanye nempilo yakho iyonke
- izici zofuzo ezingase zithinte ukwelashwa
- ukuthi umzimba wakho usabela kahle kangakanani ekwelashweni
Abantu abaningi basabela kahle ekwelashweni futhi bangena esikhathini sokuxolelwa, kodwa lokhu akunjalo kuwo wonke umuntu. Abanye abantu bangase badinge imigqa eminingana yokwelashwa ukuze bakwazi ukulawula isifo sabo. Kodwa-ke, noma ngabe uthola impendulo enhle kusenesikhathi, i-PTCL ivamise ukuphinda ibuye futhi idinga ukwelashwa okwengeziwe. Kubalulekile ukuba nokulindela okucacile mayelana nokwelashwa kwakho ukuze ukwazi ukuhlela lokho okudingayo. Chofoza isixhumanisi esingezansi ukuze uthole ezinye izinto okufanele uzicabangele lapho uthola ukwelashwa.
Ukusinda, ukuhlala ne-PTCL nangemva kwayo
Indlela yokuphila enempilo, noma ezinye izinguquko ezinhle zokuphila ngemva kokwelashwa zingaba usizo olukhulu ekululameni kwakho. Ziningi izinto ongazenza ukukusiza ukuthi uphile kahle nge-PTCL.
Abantu abaningi bathola ukuthi ngemva kokuxilongwa umdlavuza, noma ukwelashwa, ukuthi izinhloso zabo nezinto eziza kuqala ekuphileni ziyashintsha. Ukwazi ukuthi kuyini 'okujwayelekile kwakho okusha' kungase kuthathe isikhathi futhi kukhungathekise. Okulindelekile komndeni wakho nabangane kungase kwehluke kokwakho. Ungase uzizwe uhlukanisiwe, ukhathele noma iyiphi imizwa ehlukene engashintsha usuku ngalunye.
Imigomo ngemva kokwelashwa
Imigomo eyinhloko ngemva kokwelashwa kwe-PT yakhoCL wukubuyela ekuphileni futhi:
- khuthala ngangokunokwenzeka emsebenzini wakho, emndenini, nakwezinye izindima zempilo
- nciphisa imiphumela emibi kanye nezimpawu zomdlavuza kanye nokwelashwa kwawo
- khomba futhi ulawule noma yimiphi imiphumela emibi ngemva kwesikhathi
- ukusiza ukugcina uzimele ngangokunokwenzeka
- ngcono izinga lakho lempilo futhi ugcine impilo enhle yengqondo
Ukuvuselelwa Komdlavuza
Izinhlobo ezahlukene zokuvuselela umdlavuza zinganconywa kuwe. Lokhu kungasho noma yiluphi uhlobo olubanzi yezinkonzo ezifana nalezi:
- ukwelashwa ngokomzimba, ukuphathwa kobuhlungu
- ukuhlela okunomsoco nokuzivocavoca
- ukwelulekwa ngokomzwelo, kwezemisebenzi nakwezezimali.
Isifinyezo
- I-Peripheral T-cell Lymphoma (PTCL) igama elisetshenziselwa iqembu elingavamile le-T-cell Non-Hodgkin Lymphomas.
- I-PTCL yenzeka lapho ama-T-cell lymphocyte noma amaseli e-NK eba nomdlavuza.
- Amaseli e-NK angama-T-cell akhethekile ahlala esebenza futhi elungele ukuthola nokubhubhisa amaseli anomdlavuza.
- Amanye ama-T-cell alinda ukuthi asebenze amanye amaseli omzimba ukuze alwe nokutheleleka kanye nezifo. Kunezinhlobo ezahlukene zama-T-cell anemisebenzi ehlukene.
- Ama-T-cell angahamba aye kunoma iyiphi ingxenye yomzimba wakho, ngakho i-PTCL ingaba kunoma iyiphi ingxenye yomzimba wakho.
- Izimpawu ye-PTCL ingase ihlobane nohlobo oluncane nendawo ye-lymphoma yakho futhi ingase ihlanganise B-izimpawu.
- Bika zonke izimpawu ezintsha noma eziba nzima kudokotela wakho. Bangasebenzisa lolu lwazi ukuze benze izinqumo ezinhle mayelana nokunakekelwa kwakho kwezempilo, okuhlanganisa nezinketho zokwelapha.
- I-PTCL ingase isabele kahle ekwelashweni, kodwa futhi ingaba yinqaba noma ibuyele emuva ngemva kokuxolelwa ngakho ungase udinge izinhlobo zokwelashwa ezingaphezu koyedwa, ngezikhathi ezahlukene.
- Khuluma nodokotela wakho mayelana nalokho okulindele ukwelashwa kwakho.
- Awuwedwa, Abahlengikazi bethu Be-Lymphoma Care bakhona ukuze bakusekele. Ungaxhumana nabo ngokuchofoza inkinobho ethi “Thintana nathi” ezansi kwesikrini.
