New Therapies, New Challenges

On the 1st of May, 2018 immunotherapy became available on the PBS for eligible Australian patients for relapsed/refractory classical Hodgkin lymphoma.

This listing filled a huge unmet need for a small group of patients who had very limited options for a great outcome prior to this therapy becoming available.

Genomics, research and clinical evidence all came together to give patients in Australia – and across the world – access to a treatment that could give them back their lives.

As a testament to the great health system that we have in Australia, this treatment is now listed on our PBS after it was submitted to the Pharmaceutical Benefits Advisory Committee (PBAC). However, it became immediately evident relevant clauses had been overlooked in the negotiation process denying some eligible patients access from the 1st of May, says Lymphoma Australia CEO, Sharon Winton.

What appeared to be a simplistic change had to now meet the requirements of the important components that underpin our health system. Patient safety, treatment outcomes and cost effectiveness still needed to be considered by all stakeholders to ensure the appropriate wording was delivered in the latest decision-making process.

Our Health Minister Hon Greg Hunt MP, the Minister’s office, PBAC (Pharmaceutical Benefits Advisory Committee, the Department of Health, MSD, clinicians and Lymphoma Australia worked tirelessly to deliver a solution in a matter of days.

If you think you may be eligible for this treatment, please discuss this with your treating clinician and further information can also be found on the PBS website.  https://www.humanservices.gov.au/organisations/health-professionals/enablers/hodgkin-lymphoma 

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Please note: Lymphoma Australia staff are only able to reply to emails sent in English language.

For people living in Australia, we can offer a phone translation service. Have your nurse or English speaking relative call us to arrange this.

Useful Definitions

  • Refractory: This means the lymphoma does not get better with treatment. The treatment didn’t work as hoped.
  • Relapsed: This means the lymphoma came back after being gone for a while after treatment.
  • 2nd line treatment: This is the second treatment you get if the first one didn’t work (refractory) or if the lymphoma comes back (relapse).
  • 3rd line treatment: This is the third treatment you get if the second one didn’t work or the lymphoma comes back again.
  • Approved: Available in Australia and listed by the Therapeutics Goods Administration (TGA).
  • Funded: Costs are covered for Australian citizens. This means if you have a Medicare card, you shouldn’t have to pay for the treatment.[WO7]

You need healthy T-cells to make CAR T-cells. For this reason, CAR T-cell therapy cannot be used if you have a T-cell lymphoma – yet.

For more information on CAR T-cells and T-cell lymphoma click here. 

Special Note: Although your T-cells are removed from your blood for CAR T-cell therapy, most of our T-cells live outside of our blood – in our lymph nodes, thymus, spleen and other organs.