Mushonga webhayoloji mushonga une chinhu chimwe kana kupfuura chinoshanda chinogadzirwa kana kutorwa kubva mumasero mapenyu kana zvipenyu.
Chii chinonzi Biosimilar?
Biological medicine's inowanzo umbwa nemaprotein anongo gadzirwa mumuviri uye anogadzirwa kuti arape magomarara mazhinji anosanganisira lymphoma.
Kana mushonga webiological wagadzirwa mushonga wacho unoiswa pasi pe patent. Patent irezinesi rinopa mugadziri wepakutanga wemushonga kodzero yepamutemo yekuve mumwe chete pamusika kwemakore akati wandei. Kana patent iyi yapera mamwe makambani anogona kugadzira mishonga yakaita semushonga wepakutanga webiological uye iyi inodaidzwa kuti biosimilar medicine.
Mishonga yeBiosimilar yakafanana nemishonga yepakutanga uye inogona kushandiswa kurapa zvirwere zvakafanana nenzira yakafanana nemishonga yebhayoloji. Iyi mishonga yebiosimilar yakaedzwa uye yakaratidza kuve yakachengetedzeka uye inoshanda semishonga yekutanga yebhayoloji.
Ndeapi biosimilars ari kushandiswa mu lymphoma?
Granulocyte colony stimulating factor (G-CSF)
Parizvino kune mishonga mishanu yebiosimilar yakatenderwa neTGA muAustralia kuti ishandiswe mukugadzirisa lymphoma. Mushonga wekutanga webhayoloji ndeye filgrastim iyo yakagadzirwa nekambani yemishonga Amgen uye ine patent pasi pezita rekutengesa Neupogen™. Filgrastim imhando yakagadzirwa nemunhu yegranulocyte colony stimulating factor (G-CSF) chinova chinhu chinogadzirwa nemuviri kukurudzira kukura kwemaneutrophils.
Sezvo maneutrophils ari rudzi rwewhite blood cell iyo yakakosha mukurwisa kwemuviri kurwisa utachiona, filgrastim inogona kupihwa kuvarwere vari kurapwa lymphoma yavo kubatsira kutsigira neutrophil count yavo inodzikiswa nekurapa kwavanenge vachigamuchira kana mudosi yepamusoro. unganidza varwere masero kubva mumwongo kuenda kuropa remukati kuti riunganidzwe pamushini weapheresis. Pakangobuda mushonga uyu patent mamwe makambani akakwanisa kugadzira mushonga webiosimilar uye parizvino kune matatu biosimilars efilgrastim muAustralia ane mazita ekutengesa Nivestim™ akagadzirwa naPfizer, Tevagrastim™ akagadzirwa naTeva neZarzio™ akagadzirwa naSandoz.
Rituximab
Rituximab (MabThera) ndeimwe yekutanga yakaoma monoclonal antibodies kuve nebiosimilar yakabvumidzwa muAustralia. Parizvino kune maviri biosimilars e rituximab muAustralia ane mazita ekutengesa Riximyo anogadzirwa naSandoz uye Truxima anogadzirwa neCelltrion.
Vanotongwa uye kubvumidzwa sei?
A biosimilar inopfuura nemubvunzo wakakura murabhoritari uye mumakiriniki madiki miedzo kuti ienzanise nemushonga wekutanga. Inofanirwa kuenderana mumhando, chengetedzo, uye kugona (kuti inoshanda sei).
Zvadaro muedzo mukuru wekliniki unoitwa muboka revanhu vane chirwere icho chepakutanga chinoshandiswa. Izvi ndezvekusimbisa kuti kuchengeteka uye kushanda zvakanaka kunofanana nepakutanga.
Iyo biosimilar haifanirwe kuongororwa muchirwere chese icho chepakutanga chakatenderwa. Ongororo idzi dzakaitwa nemishonga yepakutanga saka patova nehumbowo hwekuti mushonga unoshanda muzvirwere izvozvo. Kana iyo biosimilar ichishanda zvakanaka mu1 yavo, hapana chikonzero chaizotadza kuita nenzira imwechete mune vamwe.
Nei vakakudziridzwa?
Kuvepo kwemabiosimilars kunowedzera makwikwi. Makwikwi anofanira kudzikisa mitengo. Kukopa mushonga unobudirira kunokurumidza kupfuura kugadzira mushonga mutsva. Makiriniki mashoma anodiwa kana zvave kutozivikanwa kuti mushonga unoshanda machiri zvirwere zvipi. Biosimilars kazhinji yakachipa zvakanyanya kupfuura mushonga wepakutanga kunyangwe mhando yemishonga yakafanana.
Mibvunzo inowanzobvunzwa
Biosimilar mishonga inogona kushandiswa kunyangwe iwe watanga kurapwa neBiologic.
Chipatara chako chinogona kushandura mhando dze rituximab sezvo biosimilars inowanikwa. Rituximab biosimilars inongopihwa intravenously (kuburikidza nekudonha mutsinga). Kana iwe uchitova ne intravenous rituximab, chipatara chako chingada kuti uchinje mabhureki kana zvichidikanwa. Vanogona kuchinja kana vasina brand yako yazvino mustock. Chiremba wako kana wemishonga anogona kupindura chero mibvunzo yaungave nayo nezvekuchinja mabhureki.
Chete mhando ye subcutaneous rituximab (yakapihwa nejekiseni pasi peganda) iripo parizvino. Kana iwe uine subcutaneous rituximab (nejekiseni pasi peganda), unogona kuenderera mberi neizvi pakurapa kwako.
Taura nachiremba kana mukoti ari kukupa mushonga. Ivo vanozokwanisa kupindura chero mibvunzo yaungave nayo pamusoro pekuchinja mabhureki.
MaBiosimilars anosiyana nemishonga yemazuva ese sezvo mishonga yemazuva ese iri chinhu chimwe chete chinoshanda semushonga wekutanga wemakemikari. Muenzaniso wemushonga wegeneric ndiwo mushonga wekutanga wemakemikari paracetamol yaive patented sePanadol™ uye mishonga yegeneric inosanganisira Panamax™ neHerron™ semuenzaniso.
