Nambarada Lymphoma
#3
#6
Lymphoma waxay soo baxdaa marka hiddo-wadahaagu isbeddelo taasoo ay sabab u tahay dhaawac ama isbeddello, taasoo keenta in cudurkaaga la dagaallanka lymphocytes uu u kobco si aan caadi ahayn oo uu noqdo kansar. Hidde-sideyaashayadu waxay bixiyaan tilmaamo ku saabsan sida loo sameeyo lymphocyte, u koraan, u dhaqmaan, iyo goorta ay dhimanayaan.
Natiijadu waxay tahay isbeddellada hidde-sideyaasha, lymphocytes waxay bilaabaan inay sameeyaan wax khaldan, sababtoo ah hadda kama helayaan tilmaamaha saxda ah ee hidda-socodkaaga. Halkii ay u kori lahaayeen si nidaamsan wakhtiga saxda ah, waxay sii wadaan samaynta unugyo badan oo waxyeeloobay oo leh hidde-is-bedelka.
Ma garanayno sababta tani u dhacdo. Ma jirto sabab sugan oo ah lymfoma mana jirto si loo sheego cidda qaadaysa iyo cidda aan qaadin.
Qaar ka mid ah arrimaha khatarta ah ayaa la aqoonsaday, kuwaas oo laga yaabo inay kordhiyaan halista aad ku qaadi karto lymphoma, laakiin maahan sababta keentay.
Waa maxay farqiga u dhexeeya arrin khatar ah iyo sabab?
A khatarta halista waa wax kordhinaya fursadahaaga inaad qaadid lymphoma, laakiin macnaheedu maaha inaad qaadi doonto lymphoma.
Ka fakar bakhtiyaanasiibka. Haddii aad ka iibsato tigidho ka badan qof kale, waxaad leedahay fursado badan oo aad ku guuleysan karto. Laakiin ma jirto wax dammaanad ah oo aad ku guuleysan doonto, qofka tigidhada yar haystaa way yar tahay, laakiin weli wuu guulaysan karaa.
Waxay la mid tahay arrimaha khatarta ah. Haddii aad leedahay arrin khatar ah waxaad leedahay mid sare fursad Qaadashada lymphoma marka loo eego qof aan lahayn khatarta khatarta ah, laakiin macnaheedu maaha inaad qaadi doonto. Iyo, sababtoo ah qofku ma laha khatarta khatarta ah, macnaheedu maaha in aanay qaadi doonin lymphoma.
Markaa arrinta khatarta ahi waa sida ciyaarta fursadda oo kale.
Halka haddii ay wax jiraan sababaha cudur, waxaynu ognahay in haddii ay taasi dhacdo, uu cudurku ka daba imanayo, haddii aanay taasi dhicinna, cudur ma jiro.
Waxaad ka fikiri kartaa sabab sida karinta ukunta. Waxaan ognahay in haddii aad jabiso ukunta, ku rid digsiga oo aad shido kulaylka ay karsanayso. Laakin haddii aad jebiso, ku rid digsiga, laakiin ha shidin kulaylka, ukunta way fadhiisan doontaa, weligeedna lama karin.
Kuleylka ayaa keena in ukunta ay karsato. Ma aha wax khatar ah, sababtoo ah mar kasta oo aad kuleyl ku kiciso xaaladdan beedku way karsanaysaa, mar kasta oo uu kuleel waayo, ukunku ma kari doono.
Dr Mary Ann Anderson - dhakhtarka dhiiga
Xarunta Kansarka ee Peter MacCallum & Isbitaalka Royal Melbourne waxay ka hadlaan sababta lymphoma u horumarto.
Maxay yihiin arrimaha khatarta ah ee la yaqaan?
Hoos waxaad ka heli doontaa arrimo halis ah oo la og yahay inay kordhiyaan fursadda aad ku qaadi karto lymphoma ama CLL. Dhammaan arrimaha khatarta ah kuma xirna dhammaan noocyada hoosaadka ee lymfoma. Meesha uu jiro nooc-hoosaad gaar ah oo la xidhiidha arrimaha khatarta ah ee aan ku darnay nooca-hoosaadka. Haddii aan la sheegin nooca-hoosaadka, markaa qodobka khatarta ahi waa arrin khatar guud ah oo kordhin karta khatartaada mid ka mid ah noocyada hoose.
Haddii aad jeclaan lahayd inaad wax badan ka ogaato noocaaga hoosaadka, waxaad riixi kartaa isku xirka hoose. Haddii kale, dhagsii falaarta ku xigta arrimaha halista ah ee hoose si aad wax badan u barato.
Sida aad ka arki karto bannerka sare ee bogga, lymphoma waa kansarka ugu badan ee ku dhaca dhalinyarada iyo dhalinyarada da'doodu u dhaxayso 15-29 sano jir. Hodgkin Lymphoma waxay ku badan tahay da'daan, laakiin waxay sidoo kale qaadi karaan Lymphoma Non-Hodgkin. Lymphoma sidoo kale waa kansarka 3aad ee ugu badan ee carruurta ka yar 15 sano.
Si kastaba ha ahaatee, khatarta qaadista lymphoma waxay kordhisaa da'da. Inta badan dadka qaba lymphoma ama CLL waa 60 sano ama ka weyn.
Lymphoma lagama dhaxlo waalidkaa, laakiin, haddii aad leedahay xubin qoyska ka mid ah oo qaba lymfoma ama CLL, waxaa laga yaabaa inaad halis dheeraad ah u yeelato inuu kugu dhaco.
Tani ma aha sababtoo ah cudurrada qoyska, laakiin waxay noqon kartaa sababtoo ah qoysaska waxay la kulmi karaan noocyo kala duwan oo halis ah - sida kiimikooyinka ama caabuqyada. ama xanuunada habdhiska difaaca ee laga yaabo inay ku dhex socdaan qoysaska.
Nidaamka difaacayagu wuxuu naga ilaaliyaa caabuqyada iyo cudurrada, sidoo kale wuxuu caawiyaa hagaajinta iyo baabi'inta unugyada dhaawacan ama kansarka. Haddii aad hore u soo booqatay boggayaga internetka Fahamka nidaamkaaga lymphatic iyo difaaca jirka, waxaad ku arki kartaa adigoo gujinaya halkan.
Haddii aad leedahay habka difaaca jirka oo hoos u dhacay - taasoo la micno ah inuusan u shaqayn sidii la rabay, waxaa laga yaabaa inaad halis dheeraad ah ugu jirto infekshannada oo aad yeelato lymphoma.
Waxyaabaha xakameyn kara habka difaaca jirka waxaa ka mid ah kuwan soo socda.
Daawooyinka difaaca jirka iyo daawaynta
Haddii aad daawo qaadanayso si aad u cabudhiso habka difaacaaga waxa ay kordhin kartaa halista aad ugu qaadi karto lymphoma iyo kansarro kale. Tusaalooyinka kuwan waxaa ka mid noqon kara daawooyinka loo qaato cudurrada difaaca jirka, ama ka dib xubinta taranka ama tallaalka unugyada stem allogeneic. Lymphomas-ka soo baxa ka-tallaalidda ka dib waxa loo yaqaan "Post-Transplant Lymphoproliferative Disorder (PTLD)".
Chemotherapy iyo daawaynta kale ee kansarka sida radiotherapy iyo qaar ka mid ah unugyada unugyada monoclonal ayaa sidoo kale xakameyn kara habka difaaca jirka.
Had iyo jeer kala hadal dhakhtarkaaga wixii khatar ah ee ay keeni karaan daawooyinkaaga iyo daawaynta kale.
Xanuunada difaaca jirka
Cilladaha difaaca jirka waa cillado ku dhaca habka difaacaaga. Dadku waxay ku dhalan karaan cudurradan ama waxay ku dhici karaan noloshooda dambe.
Cilladaha difaaca ee aasaasiga ah waa kuwa aad ku dhalatay waxaana ka mid noqon kara:
- Immuneficiency X-linked ee lagu dhasho
- Ataxia Telangiectasia
- Wiskott-Aldrich syndrome.
Xanuunada difaaca jirka ee labaad waa xaalado aan "helno" inta lagu jiro nolosheenna, ama ku dhaca sabab kale - sida marka kiimoterabiga uu keeno nutropenia taasoo keenta difaac la'aan. Acquired Immun Deficiency Syndrome (AIDS) waa nooc kale oo ka mid ah cilladda labaad ee difaaca jirka, inta badan waxaa keena fayraska difaaca jirka (HIV).
Dhibaatooyinka Autoimmune
Xanuunada difaaca jirka waa xaalado habka difaaca jirkaagu uu bilaabo inuu weeraro unugyada caafimaadka qaba. Waxaa jira noocyo badan oo kala duwan oo ah cilladaha difaaca jirka, qaarna waxaa loo aqoonsaday inay kordhinayaan halista nooc-hoosaadyada lymphoma oo ay ku jiraan:
- Sjogren's syndrome - khatarta sii kordheysa splenic iyo MALT lymphomas zone marginal.
- Hashimoto's thyroiditis - waxay kordhisaa khatarta ah MALT aagga marginal lymphoma.
- Cudurka Celiac - wuxuu kordhiyaa halista Enteropathy-Associated T-Cell Lymphoma (EATL), oo ah nooc-hoosaad Unugyada T-Cell Lymphoma (PTCL)
- Rheumatoid arthritis-ku wuxuu kordhiyaa halista Lymphoma Aagga Marginal splenic iyo Ballaarinta B-Cell Lymphoma Weyn.
Infekshannada qaarkood waxay kordhin karaan halista aad ugu qaadi karto lymphoma. Badanaa infekshannadani waa caabuqyo aynu ku qaadno carruurnimada qaar badanina waa kuwo aan laga fursan karin. In kasta oo infekshannadani ay kordhin karaan halista aad ugu qaadi karto lymfoma dambe ee nolosha, dad badan oo qaba caabuqyadaan ma yeeshaan lymphoma, dadka aan weligood qaadin caabuqan waxay weli qaadi karaan lymphoma.
Fayraska Epstein-Barr (EBV)
EBV ayaa loo aqoonsaday inay tahay arrin halis u ah dhowr nooc oo hoosaadyo kala duwan oo lymphoma ah. Waa nooc ka mid ah fayraska herpes oo bedeli kara habka ay u shaqeeyaan unugyadeena B. EBV waa fayraska keena qandhada qanjidhada, kaas oo sidoo kale mararka qaarkood loo yaqaan "cudurka dhunkashada" sababtoo ah waxaa laga gudbi karaa candhuufta. Waxa kale oo mararka qaarkood loo yaqaan mononucleosis ama "mono". Qaar ka mid ah noocyada hoosaadyada lymphoma ee la xidhiidha EBV waxaa ka mid ah:
- Burkitt Lymphoma
- Faafi Lymphoma weyn oo B-cell ah
- Hodgkin Lymphoma
- Lymphomas T-cell
- Cudurka qanjirka 'lymphoproliferative transplant' ka dib ka dib tallaalka unugyada stem allogeneic.
Helicobacter Pylori (H. Pylori)
H. Pylori waa infekshan sababa boogaha caloosha, wuxuuna kordhiyaa halista inaad ku korto Gastric MALT Lymphoma Aagga Marginal.
Campylobacter jejuni & Borrelia burgdorferi
Campylobacter jejuni waa bakteeriya inta badan sababta cunto ku sumowga calaamadaha ugu caansan waa qandho iyo shuban. Borrelia burgdorferi waa infekshan bakteeriya ah oo sababa cudurka Lyme.
Labadan jeermisyada bakteeriyadu waxay kordhin karaan khatarta ah inaad horumarto MALT Aagga Marginal Lymphoma.
Fayraska T-lymphotropic ee aadanaha 1 iyo 2
Fayraskani waa naadir Australia wuxuuna aad ugu badan yahay koonfurta Japan iyo Kariibiyaanka si kastaba ha ahaatee, wali waxa laga helaa qaybo ka mid ah Australia. Waxa lagu kala qaadaa galmo aan la ilaalin oo lala yeesho qof fayraska qaba, dhiig wasakhaysan ama irbado iyo caanaha naaska. Fayraska T-lymphotropic ee bini'aadamka wuxuu kordhin karaa khatarta ah inaad yeelato nooc ka mid ah lymphoma oo la yiraahdo Dadka waaweyn ee T-cell Leukemia/Lymphoma.
Fayraska karti la'aanta kartida aadanaha (HIV)
HIV waa fayraska keeni kara Acquired Immune Deficiency Syndrome (AIDS). Waxa lagu kala qaadaa galmo aan la ilaalin oo lala yeesho qof qaba fayras, dhiig wasakhaysan iyo irbado wasakhaysan, iyo mararka qaarkood hooyada ilaa ilmaha wakhtiga uurka, dhalashada ama naaska nuujinta. Qabashada HIV waxay kordhin kartaa halista Hodgkin iyo non-Hodgkin Lymphomas labadaba. HIV ama AIDS-ka lymfomasyada laxidhiidha waa kuwa dagaal badan oo leh lymphomas-yada ugu badan ee AIDS-ka la xiriira Ballaarinta B-Cell Lymphoma Weyn iyo Burkitt Lymphoma, inkastoo ay sidoo kale kordhin karto khatartaada Nidaamka neerfaha ee aasaasiga ah ee 'Lymphoma' iyo Dhiig-baxa Hore ee Lymphoma.
Human Herpesvirus-8 (HHV8) - sidoo kale loo yaqaan Kaposi Sarcoma Herpesvirus (KSHV)
HHV8 waxaa sidoo kale loo yaqaan Kaposi Sarcoma Herpesvirus sababtoo ah waxay keeni kartaa Kaposi sarcoma, kaas oo ah kansar naadir ah oo ku dhaca dhiigga iyo marinnada qanjidhada. Si kastaba ha ahaatee, waxaa sidoo kale loo aqoonsaday inay tahay arrin halis u ah horumarinta lymphoma-ka hoose oo aad dhif u ah oo loo yaqaan 'Primary Effusion Lymphoma'.
Fayraska Cagaarshowga C (HCV)
HCV waa caabuq u keena caabuq beerkaaga. Waxa kale oo ay keeni kartaa xaalad loo yaqaan 'cryoglobulinemia' taas oo keeni karta koritaanka unugyada aan la xakameynin - laakiin aan ahayn kansar. Si kastaba ha ahaatee, waxa laga yaabaa in ay is beddesho muddo ka dib oo ay noqoto kansar, taas oo kordhinaysa khatartaada Unugyada B-non-Hodgkin Lymphomas.
Soo-gaadhista kiimikooyinka qaarkood ayaa loo aqoonsaday inay tahay arrin khatar ku ah Hodgkin Lymphoma iyo noocyada kala duwan ee Non-Hodgkin Lymphomas. Khatartaadu way korodhay haddii aad isticmaasho ama samayso alaabtan.
Waxaa laga yaabaa inaad halis dheeraad ah ugu jirto inuu ku dhaco lymphoma haddii aad ka shaqeyso meelaha isticmaala ama soo saarayaasha alaabta sida:
- sunta cayayaanka
- doogga xoolaha
- dawooyinka loo adeegsado fungus
- noolaha faafa
- dareerayaasha
- rinjiga
- shidaal
- saliidaha
- boodh
- timaha midabaynta.
Haddii aad ka shaqayso meelahan aad bay muhiim u tahay inaad u isticmaasho qalabka ilaalinta shakhsi ahaaneed ee lagu taliyey ee warshadahaaga iyo alaabtaada.
Cilmi-baadhisyada qaar ayaa soo jeediyay in beeralayda, kuwa alwaaxyada ka shaqeeya, kormeerayaasha hilibka iyo dhakhaatiirta xoolaha laga yaabo inay kordhiyaan khatarta, si kastaba ha ahaatee cilmi-baaris dheeraad ah ayaa loo baahan yahay si loo xaqiijiyo tan.
Lymphoma unug weyn oo anaplastic ah oo la xidhiidha naasaha
Tallaalka naasaha ayaa loo aqoonsaday inay tahay arrin halis u ah nooca-hoosaadka T-unugga ee Non-Hodgkin Lymphoma oo tartiib tartiib u koraya (ALCL). Way ka badan tahay meesha maqaar-galaha textured la isticmaalay halkii la isticmaali lahaa maqaar-galaha siman.
Inkasta oo kansarkani uu ka bilaabmo naaska, ma aha nooc ka mid ah kansarka naasaha. Waxaa loo malaynayaa inay sababto jeebabka dareeraha, caabuqa ama caabuqa oo ku soo koraya agagaarka maqaar-galaha kaas oo, muddo ka dib isu bedeli kara ALCL. Haddii aad qabtid ALCL-ka-xiran naasaha, dhakhtarkaagu wuxuu kugula talin doonaa in lagugu sameeyo qalliin si aad uga saarto maqaar-galaha iyo wixii dareere ah ama caabuq ah ee la helo. Tani waxay noqon kartaa daawaynta kaliya ee aad u baahan tahay, si kastaba ha ahaatee haddii ay ku fiday qaybaha kale ee jidhkaaga, waxaa lagugula talin doonaa daawayn kale sidoo kale. Waxaad wax badan oo arrintan ku saabsan ka baran kartaa adigoo gujinaya xiriirka hoose.
Daaweynta kansarka
Nasiib darro qaar badan oo ka mid ah daawaynta loo isticmaalo daawaynta kansarka ayaa sidoo kale keeni kara kansarrada labaad. Kansarradani maaha kuwo la mid ah kansarka ugu horreeya oo looma tixgeliyo soo noqoshada. Khatarta ah inuu ku dhaco kansar labaad sida lymfoma waxay ahaanaysaa sanado badan ka dib daawayntaada.
Daawaynta sida kiimoterabiga, shucaaca iyo daawaynta kale ee hoos u dhigaysa nidaamka difaacaaga, ama waxyeelaya limfosaytiskaaga waxay kordhisaa khatarta ah inaad ku dhacdo lymphoma.
Haddii lagaa daweynayo nooc kasta oo kansar ah oo ay ku jiraan lymphoma, weydii dhakhtarkaaga khatarta kansarka labaad.
Monoclonal B-cell lymphocytosis
Monoclonal B-cell lymphocytosis (MBL) waa xaalad aan kansar ahayn oo sababta tirada korodhka ah ee unugyada B-unugyada lymphocytes ee aan caadiga ahayn ee dhiigga. Unugyada B-lymphocytes ee aan caadiga ahayn waxay leeyihiin sifooyin la mid ah kuwa leukemia-da daba-dheeraada (CLL), nooc-hoosaadka Lymphoma Non-Hodgkin.
MBL waxaa loo tixgeliyaa xaalad kansar ka hor oo isu beddeli karta CLL muddo ka dib. Si kastaba ha ahaatee, qof kasta oo qaba MBL ma yeelan doono CLL.
MBL aad bay ugu yar tahay dadka da'doodu ka yar tahay 40 sano, khatarta ah in ay qaadaan MBL waxay kordhisaa da'deena.
nololeedka
Si ka duwan kansarrada kale, waxaa jira caddayn aad u xaddidan oo sheegaya in lymphoma ay sababto doorashooyinka qaab nololeedka. Si kastaba ha ahaatee, doorashooyinka qaarkood (sida nadaafad xumo, galmo aan la ilaalin ama wadaaga irbadaha) waxay kordhin karaan halista aad u qaadi karto qaar ka mid ah fayrasyada iyo caabuqyada kale, halka kuwa kale (sida jimicsi la'aanta jirka, ama nafaqo xumo) ay hoos u dhigi karto shaqadaada difaaca. Caabuqyadan, ama difaac la'aanta waxay kordhin karaan halista aad ugu qaadi karto lymphoma.
Joogteynta qaab nololeed caafimaad leh waxay hoos u dhigi kartaa halista aad ku qaadi karto lymphoma, inkastoo aysan jirin dammaanad qaadka. Dad badan oo laga helay lymphoma waxay ku nool yihiin qaab nololeed caafimaad leh. Si kastaba ha ahaatee, inkasta oo doorashada qaab nololeedkaaga laga yaabo inaysan si buuxda kaaga ilaalinin inaad qaadatid lymphoma, inaad si kale u caafimaad qabto haddii aad u baahan tahay inaad daawato, waxay jidhkaaga ka caawin doontaa inuu si fiican u qabsado oo uu dhaqso u soo kabsado.
Qaar ka mid ah doorashooyinka caafimaadka leh ee la tixgeliyo waxaa ka mid ah:
- Ha bilaabin sigaarka, ama hel caawimo si aad u joojiso.
- Ka fogow daroogooyinka sharci darrada ah.
- Haddii aad u baahan tahay inaad isticmaasho cirbadaha sabab kasta, hal mar isticmaal oo ku rid weel ku habboon si aad u tuurto. Ha la wadaagin cirbadaha dadka kale.
- Haddii aad khamri cabto, cab si dhexdhexaad ah.
- Ujeedo ugu yaraan 30 daqiiqo jimicsi jireed maalin kasta. Haddii dhaqdhaqaaqa jirku kugu adag yahay, u tag dhakhtarka deegaanka.
- Cun cunto caafimaad leh. Haddii aad u baahan tahay caawimaad tan, takhtarka deegaanka ayaa kuu diri kara dhakhtarka cuntada.
- Ku raaxayso, laakiin ku badbaadi habka.
Summary
- Lymphoma waxay soo baxdaa marka ay isbeddesho - oo sidoo kale loo yaqaan isbeddellada ayaa ku dhaca hidde-sideyaashaada oo saameeya habka lymphocytes-kaaga u koraan oo u shaqeeyaan.
- Ilaa hadda ma jiraan sababo la garanayo oo keenaya isbeddelkan keenaya lymphoma.
- Qodobbada khatarta ahi waxay kordhin karaan fursadda aad ku qaadi karto lymfoma, laakiin haddii aad leedahay arrin khatar ah, macnaheedu maaha inaad qaadi doonto lymphoma.
- La'aanta arrin khatar ah macnaheedu maaha inaadan qaadi doonin lymphoma.
- Lymphoma ma aha kansar "qaab nololeed" - uma eka inay sababto doorashooyinka qaab nololeedka sida kansarrada kale.
