Neuropathy peripheral wuxuu noqon karaa calaamadda lymfoma waana saameyn caadi ah oo ku timaada daawaynta lymphoma qaarkood. Waxa sababa dhaawaca ku meel gaadhka ah ama joogtada ah ee neerfayaasha habdhiska dareenka. Waxyeelladani waxay keeni kartaa dareen beddela sida:
- kabuubyo
- biin iyo irbado
- xanuun
- dareen gubasho
- isbedel ku yimaada dareenka galmada
- musqusha aadeyso.
Boggani wuxuu inta badan diiradda saari doonaa neuropathy durugsan guud ahaan, laakiin haddii aad jeclaan lahayd macluumaad dheeraad ah oo ku saabsan isbeddelada galmada iyo isu soo dhawaanshaha, ama isbeddellada mindhicirka marka la daweynayo, fadlan guji xiriirka hoose.
Waa maxay habdhiska dareenkeena?
Nidaamkeena neerfayaasha wuxuu u shaqeeyaa xoogaa sida shabakad fiilooyinka korantada ah.
Unugyo gaar ah (Reseptors) iyo neerfayaasha ku jira habdhiska dareenkeena ayaa soo qaada oo sita calaamadaha (farimaha) inta u dhaxaysa maskaxdeena iyo qaybaha kala duwan ee jidhkeena. Calaamadahani, waxay si joogto ah u shaqeeyaan waxayna u sheegaan jidhkeenu inuu ogaado sida loo shaqeeyo, iyo sida loo fahmo aduunka nagu wareegsan, iyada oo loo marayo dareenkeena dhadhanka, urta, codka, taabashada, dheelitirka iyo booskeena.
Nidaamkeena neerfayaasha ayaa sidoo kale mas'uul ka ah dhaqdhaqaaqa iyo murqaha muruqyada. Waxay macluumaad siisaa wadneheena, sambabada, mindhicirka iyo dhammaan xubnahayaga si ay u ogaadaan marka ay qandaraasayaan oo ay nasanayaan.
Si kastaba ha noqotee, haddii aad leedahay neuropathy peripheral, fariimahan waa la carqaladeeyay, markaa dareenka jidhkaaga ayaa isbeddeli kara.
Dareenka dhexe iyo habdhiska dareenka
Nidaamkeena dhexe ee neerfayaasha waxay ku lug leeyihiin dhammaan neerfayaashayada iyo kuwa qaata maskaxda, xudunta laf dhabarta iyo aagga indhahayaga gadaashiisa. Waxay heli kartaa oo ay u diri kartaa fariimaha habdhiska dareenka ee durugsan si uu jidhkeenu si fiican ugu shaqeeyo.
Parasympathetic iyo Nidaamka Dareenka
Nidaamka neerfayaasha ee durugsan waa dhammaan reseptors iyo neerfayaasha kale ee ka baxsan habka dhexe ee neerfayaasha, kuwaas oo si sax ah looga helo dhammaan jirkeena. Waxay u soo diraan oo ay helaan farriimaha maskaxdayada. Waxaan leenahay habdhiska dareenka ee parasympathetic iyo naxariista oo wada shaqeeya si aan u ilaalino dhaqdhaqaaqa jirkeena.
Riix sawirka si aad u aragto sida ay u wada shaqeeyaan.
Is-maamulka, Matoorka iyo Dareemaha Dareenka
Qaybo ka mid ah habdhiska dareenka ayaa si toos ah u shaqeeya, sida kuwa calaamadaha u soo dira wadnaha, sambabada iyo mindhicirkeena. Dhaqdhaqaaqa neerfaha tooska ah ayaa loo yaqaan madax-bannaani.
Qaybaha kale ee habdhiska dareenkeena waan xakamayn karnaa, sida marka aan doorano inaan ordo, ama wax kor u qaadno ama aan yeelano dhaqdhaqaaq kale oo miyir leh. Neerfayaashan aynu gacanta ku hayno ayaa la yidhaahdaa dareemaha muruqyada.
Our dareen neerfayaasha iyo reseptors ayaa dira oo helaan farriimaha ku saabsan heerkulka iyo taabashada. Kuwani waxay naga caawinayaan inaan aqoonsanno khatarta haddii aan taabno wax aad u kulul ama qabow, ama fiiqan, oh haddii ay cadaadis badan nagu saarto.
Waa maxay neuropathy peripheral?
Peripheral neuropathy waa khalkhal ku dhaca soo-dhoweeyayaasha iyo neerfayaasha ka baxsan habdhiska dareenkaaga dhexe. Waxay dhacdaa marka xuubka dareemayaasha ama neerfayaasha ay dhaawacmaan, sidaas darteed farriimaha laga soo diro maskaxdaada ayaa istaaga, ama la ruxruxo.
Iyadoo ku xiran meesha uu dhaawacu yaallo, waxaa laga yaabaa inaad la kulanto mid ka mid ah calaamadaha hoose.
Calaamadaha Neuropathy Peripheral sida uu qabo habdhiska dareenka | ||
Dareenka neerfaha | Matoorka neuropathy | Autonomic neuropathy |
Jidhidhid, gubasho, biinanka iyo cirbadaha ama dareenka koronto ee gacmahaaga ama cagahaaga.
Luminta dareenka ama kabuubyada.
Dareenka oo u beddelay kicin. Wax dareema kulayl marka ay qabowdahay.
Luminta dheelitirka markaad indhahaaga xirto.
Luminta falcelinta.
Ku garaaca ama ka guuxaya dhegahaaga. |
Calool xanuun.
Murqo gariir.
Dareen-celinta oo yaraatay.
Muruqa oo daciif ah.
Socod aan joogto ahayn markaad socoto.
Awood la'aanta in la sameeyo badhamada si fudud.
Dhibaato qorista
Lugaha aan nasan.
Jiiditaanka, ama awoodin in aad cagaha si fiican u qaaddo markaad socoto.
|
Dawakhaad.
Kaadi-haysta way isbedeshaa.
Shuban.
Calool fadhiga
Calool-celinta kaadi-la'aanta (aanad tagin musqusha wakhtiga, ama aanad dareemin markaad u baahan tahay inaad tagto).
Dareen dhereg ka hor inta aan caadi ahayn.
Awood la'aan ama dhibaato gaarista kacsiga.
Dhidid aan caadi ahayn. |
Waa inaad u sheegtaa dhakhtarkaaga iyo kalkaaliyayaashaada haddii aad isku aragto mid ka mid ah calaamadaha kore. Waxaa laga yaabaa inaad u baahato in qiyaasta daawadaada sida kiimoterabiga la beddelo, ama laga yaabo inaad cadaadis ku yeelato neerfaha lymphoma, una baahan daaweyn kale. Arrimahan ayaa u baahan in si degdeg ah wax looga qabto. Xaalado badan, neuropathy durugsan waa la beddeli karaa haddii la daweeyo waqti hore.
Sababaha neuropathy peripheral ee lymphoma
Waxaad leedahay dhowr arrimood oo halis u ah neuropathy durugsan marka aad qabtid lymphoma. Kuwaas waxaa ka mid noqon kara lymphoma lafteeda, daawaynta, ama jirrooyinka kale ee laga yaabo inaad sidoo kale qabtid, ama aad ku samaysid daawayntaada.
Astaamaha Lymphoma
Dhammaan lymphomas-yada oo dhan ma keeni karaan neuropathy durugsan, si kastaba ha ahaatee waxaad u badan tahay inaad ku hesho calaamadda lymphoma haddii:
- Waxaad qabtaa Waldenstroms Macroglobulinemia (WM). Gudaha WM paraproteinsku waxay ku dhegi karaan unugyada dareemayaashaada oo ay waxyeelo u geystaan.
- Lymphomaaga ayaa ku koraya hareeraha dareemayaashaada oo cadaadis saaraya iyaga.
- Lymphoma-gaaga ayaa ku koraya agagaarka xididdada dhiigga ee dhiigga siiya neerfayaashaada iyo kuwa qaata, taasoo ka hortagaysa socodka dhiigga iyaga.
Saamaynta ay leedahay daawaynta caadiga ah
- Rotooterapi
- Qalliin ama habraacyo ay neerfayaasha ama daaweeyayaasha ay dhaawacmaan
- Vinca alkaloids (sida vincristine, vinblastine iyo vinorelbine) - Daawooyinkan waxaa la siiyaa qayb ka mid ah borotokoolka chemotherapy badan sida: CHOP, CHEOP, Hyper CVAD, CVP, DA-R-EPOCH, BEACOPP, ChIVPP, IGEV, PVAG
- Daawooyinka ku salaysan Platinum (sida cisplatin, carboplatin, oxaliplatin) - Kuwaas waxaa lagu siin karaa qayb ka mid ah DHAP, GDP, DDGP, DHAC, ESHAP, ICE, RICE, R-GemOx, HiDAC MATRIx
- Brentuximab vedotin - Kani waxa la siin karaa kaligiis ama qayb ka mid ah BvCHP, ama unugyada kale ee monoclonal.
- Velcade
- Thalidomide
Kani maaha liis dhamaystiran oo ah daawaynta lymfoma oo sababi karta neuropathy durugsan, iyo marka dawooyin cusub la helo liiskani wuu kordhi karaa. Waa muhiim inaad u sheegto dhakhtarkaaga iyo kalkaaliyayaasha caafimaadka calaamad kasta oo ah neuropathy durugsan si ay u go'aamiyaan sababta iyo ikhtiyaarrada daawaynta ugu fiican adiga.
Xaalado kale ama arrimo keeni kara neuropathy durugsan
Waxaa jira xaalado kale oo keeni kara neuropathy peripheral. Kuwaas waxaa ka mid noqon kara:
- Diabetes
- Vitamin B12 oo hooseeya
- Caabuqyada sida shingles
- Cudurada difaaca jirka
- Sigaarka
- Khamriga.
Caawi inaad iska dayso ama yarayso sigaarka iyo cabbidda
Maareynta shuruudaha kale
Haddii aad qabto sonkorow ama jirro difaaca jirka, waa muhiim inaad sii wadato daawayntaada kuwaas. Waxa laga yaabaa inaad u baahato inaad aragto dhawr kooxood oo takhaatiir ah si aad u hubiso in lymphoma-gaaga iyo xaaladaha kale si fiican loo xakameeyay.
Infections
Kala hadal dhakhtarkaaga dhiigga ama dhakhtarka kansarka kansarka khatartaada caabuqa iyo tallaalada badbaadada kuu ah inaad qaadato. Xaaladaha qaarkood, waxaa laga yaabaa inay ku taliyaan tallaalka shingles ama noocyada kale ee caabuqyada.
Tallaalka nool waxa laga yaabaa in aanay badbaado lahayn marka lagaa dawaynayo lymphoma, markaa iska hubi inaad waydiiso midda aad qaadanayso.
Daaweynta
Waxaa jira daawaynta dabiiciga ah iyo kuwa ka soo horjeeda miiska si ay u yareeyaan calaamadaha neuropathy durugsan. Xaaladaha qaarkood, isbeddelka qiyaasta daawadaada ayaa laga yaabaa inay ku filnaato si loo hagaajiyo calaamadahaaga.
Aad bay muhiim u tahay inaad ka warbixiso calaamadaha neuropathy durugsan isla marka ay bilaabaan. Sida ugu dhakhsaha badan ee qiyaasta qiyaasta ay u dhacdo waxay u badan tahay in neuropathy durugsan uu fiicnaan doono.
Daawooyinka miiska laga soo iibsado si ay uga caawiyaan neuropathy durugsan
- kareemka capsaicin
- fitamiinada - sida fiitamiinada B
- maqaarka maqaarka leh lignocaine (sidoo kale loo yaqaan lidocaine)
- glutamine.
Daawooyinka kale ee dabiiciga ah
Waxyaabaha kale ee aad isku dayi karto kuwaas oo kaa caawin doona yaraynta saameynta neuropathy durugsan waxaa ka mid ah:
- duugis dabacsan
- jimicsi si loo hagaajiyo socodka dhiigga
- daaweynta dabiiciga ah
- caafimaad cun
- diirimaadku waxay caawin kartaa dadka qaarkood, halka qaar kalena ay u arkaan qabowgu inay caawiso.
- yaree caffeine sida kafeega iyo cabitaannada tamarta. Kaafinta badan waxay saameyn kartaa socodka dhiigga waxayna ka sii dari kartaa calaamadaha. Isku day kafeega beddelka ah sida shaaha Dandelion ama shaaha cagaaran ee aan kafeyn.
Cuntooyinka kaa caawin kara dib u soo kabashada dareemayaasha
Fish | Miraha & khudaarta | Miraha & Miraha |
salmon Sardines Mackerel tuna Xeer | Spinach Avokado Digirta madow Digirta cagaaran Lentils Soyaayada Likaha manka likaha Ginger Dhammaan miraha cusub | yicibta Walxaha abuur bocorka
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Hayso biyo
Fuuqbaxa ayaa ka sii dari kara neuropathy durugsan, iyo daahida bogsashada. Cab ugu yaraan 6-8 koob oo biyo dhaadheer oo buuxa ah maalin kasta. Haddii aadan kaligiis jeclayn biyaha, isku day inaad ku darto xoogaa liin ama casiir liin ah ama xargo leh biyaha.
***Haddii uu dhakhtarkaagu ku siiyay xannibaad dheecaan ah, ku dheggan taladaas oo kaliya cab intii lagugu amray.
Daaweynta Caafimaadka
Waxaa laga yaabaa inaad u baahato daawayn caafimaad si aad u hagaajisid calaamadaha neuropathy durugsan. Kuwaas waxaa ka mid noqon kara:
- amitriptyline, duloxetine, pregabalin ama gabapentin. Kuwani guud ahaan waxay si fiican ugu shaqeeyaan xanuunka neuropathy ee ku wareegsan marka loo eego opioids.
- cannabinoids
- xididka (xididkaaga) lignocaine (lidocaine)
- Cilmiga daaweynta
- Plasmapheresis ( Plasma exchange) kaliya haddii aad qabto Waldenstroms Macroglobulinemia.
Summary
- Peripheral neuropathy waa waxyeellada caadiga ah ee daaweynta lymphoma, waxayna noqon kartaa calaamad muujinaysa lymphomas qaarkood.
- Qaar ka mid ah neuropathy agagaarkeeda waa la beddeli karaa haddii la qabto oo goor hore la maareeyo, kuwa kalena waxay ahaan karaan kuwo joogto ah.
- Peripheral neuropathy wuxuu dhacaa marka reseptors (unugyo gaar ah) iyo darafyada dareemayaasha ee ka baxsan maskaxda iyo xangulada laf dhabarta ay dhaawacmaan, ama ay socodka dhiigga iyaga xaddidan yihiin.
- Meesha miiska laga soo iibsado, daawaynta dabiiciga ah iyo kuwa daawaynta ayaa dhamaantood loo isticmaali karaa si loo hagaajiyo calaamadaha neuropathy durugsan.
- U sheeg dhammaan calaamadaha xanuunka neuropathy-ga durugsan ee dhakhtarkaaga dhiigga ama dhakhtarka kansarka ka hor daawayntaada xigta.
- Calaamadaha caanka ah waxaa ka mid noqon kara isbeddel ku yimaada dareenka gacmahaaga iyo cagahaaga, dhibaato aadista musqusha, isbeddelka shaqada galmada iyo kuwa kale ee kor ku xusan.
- Wac khadka taageerada bukaanka si aad ula hadasho mid ka mid ah Kalkaaliyaashayada Daryeelka Lymphoma haddii aad qabto iyo su'aalo ku saabsan neerfaha durugsan. Guji nala soo xiriir hoose ee shaashadda si aad u hesho faahfaahinta xiriirka.
