Ana amfani da maganin kulawa sau da yawa tare da nau'ikan lymphoma da yawa tare da manufar kiyaye lymphoma cikin gafara na tsawon lokaci.
Menene maganin kulawa?
Maganin kulawa yana nufin magani mai gudana bayan jiyya na farko ya sanya lymphoma cikin gafara (lymphoma ya rage ko ya amsa magani). Manufar ita ce a sa gafarar ta dawwama muddin zai yiwu. Mafi yawan nau'in maganin da ake amfani da shi wajen kulawa shine tare da maganin rigakafi (irin su Rituximab ko Obinutuzumab).
Chemotherapy wani lokaci ana amfani dashi azaman maganin kulawa ga yara da matasa masu ciki lymphoblastic lymphoma. Yawancin lokaci ana fara su a cikin watanni 6 na farko bayan jiyya na farko don kiyaye lymphoma daga ci gaba ko maimaituwa.
Har yaushe maganin kulawa zai kasance?
Dangane da nau'in lymphoma da magungunan da ake amfani da su, maganin kulawa na iya ɗaukar makonni, watanni, ko ma shekaru. Ba duk marasa lafiya ne ake ba da shawarar samun maganin kulawa ba idan lymphoma yana ƙarƙashin kulawa bayan shigar da jiyya. An gano yana da fa'idodi a wasu nau'ikan nau'ikan lymphoma.
Rituximab wani maganin rigakafi ne na monoclonal wanda galibi ana ba da shawarar azaman maganin kulawa a cikin marasa lafiya tare da nau'ikan lymphoma marasa Hodgkin (NHL). Waɗannan marasa lafiya yawanci sun karɓi rituximab a matsayin wani ɓangare na jiyya na shigar da su, galibi a hade tare da chemotherapy (wanda ake kira chemoimmunotherapy).
Idan lymphoma ya amsa maganin farko, ana iya ba da shawarar rituximab a ci gaba da zama 'maganin kula'. Ana gudanar da rituximab a cikin lokacin kulawa sau ɗaya kowane watanni 2-3. Rituximab a halin yanzu ana ba da iyakar tsawon shekaru 2, kodayake gwaje-gwaje na asibiti suna gwada ko akwai wani fa'ida a cikin kulawar kulawa da ke ci gaba da tsayi. Don kulawa da kulawa, ana iya ba da rituximab ta cikin jini (ta allura a cikin jijiya) ko kuma ta hanyar allura a ƙarƙashin fata.
A madadin, Obinutuzumab (Gazyva) wani maganin rigakafi ne na monoclonal wanda kuma ana amfani dashi don kulawa ga marasa lafiya da lymphoma follicular bayan chemotherapy. Ana gudanar da Obinutuzumab kowane wata 2 har tsawon shekaru 2.
Wanene ke karɓar maganin kulawa?
An yi amfani da rituximab mai kulawa a cikin ƙananan nau'ikan NHL marasa ƙarfi kamar lymphoma follicular. A halin yanzu ana duba lafiyar kulawa a cikin wasu nau'ikan lymphomas. Yara da matasa da ke da lymphoma na lymphoblastic ana iya ba su kulawar kulawa tare da chemotherapy don hana sake dawowa lymphoma. Wannan hanya ce mai ƙarancin ƙarfi ta chemotherapy.
Menene fa'idodin kula da jiyya?
Samun maganin kulawa tare da rituximab ko Obinutuzumab na iya ƙara tsawon gafara a cikin marasa lafiya tare da ƙwayar lymphoma follicular ko mantle cell. Bincike ya nuna cewa sake dawowa na iya jinkirta ko ma hana shi, ta hanyar ci gaba ko 'ci gaba da' magani tare da rituximab yayin da marasa lafiya ke cikin gafara. Manufar ita ce a hana marasa lafiyar da suka amsa maganin farko daga sake dawowa yayin da suke inganta rayuwa gaba ɗaya. A Ostiraliya, wannan ana ba da kuɗin jama'a ne kawai (PBS) don rituximab a cikin lymphoma follicular.
Haɗarin maganin kulawa
Kodayake magungunan da ake amfani da su don kula da jiyya gabaɗaya suna da ƙarancin sakamako masu illa fiye da haɗin chemotherapy, har yanzu marasa lafiya na iya fuskantar mummunan al'amura daga waɗannan jiyya. Likitan zai yi la'akari da duk yanayin asibiti kafin tantance farkon jiyya da ko majiyyaci zai amfana daga maganin kulawa da wani magani ko 'kallon da jira'.
Yawancin marasa lafiya ba su da lahani masu wahala da yawa yayin da suke kan rituximab. Duk da haka, ba koyaushe ya dace da kowa don karɓar maganin kulawa ba. Wasu daga cikin yiwuwar illolin kulawar Rituximab sune:
- Maganin rashin lafiyan
- Rage tasirin akan ƙwayoyin jini
- Ciwon kai ko mura kamar alamomi
- Wuci ko gajiya
- Canjin fata kamar kurji
Jiyya da ke ƙarƙashin bincike azaman maganin kulawa
Yawancin sabbin hanyoyin warkewa na mutum ɗaya da haɗin gwiwa ana gwada su a duk faɗin duniya don amfani da su wajen kula da ƙwayoyin lymphoma. Wasu daga cikin waɗannan magungunan sun haɗa da:
- Bortezomib (Velcade)
- Brentuximab vedotin (Adcetris)
- Lenalidomide (Revlimid)
- Vorinostat (Zolinza)
Binciken kimiyya yana ci gaba da haɓakawa. Zaɓuɓɓukan jiyya na iya canzawa yayin da aka gano sabbin jiyya kuma ana inganta zaɓuɓɓukan magani.
Bugu da ari, Information
Kuna iya samun ƙarin bayani game da maganin kulawa da kuke karɓa ta bin hanyoyin haɗin da ke ƙasa:
